A detailed mechanistic study unravels how the bacterial endotoxin LPS prevents or promotes allergic disease.

Bacteria use molecular machines to move proteins, including toxins, across cell membranes. M. tuberculosis, which kills more than 1 million people a year, uses the ESX-4 type VII secretion system to transports its potent exotoxin.

Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.

Record $95 million Heersink lead gift to advance strategic growth and biomedical innovation.

The higher infectivity correlates with mutations that increase viral binding to a cell surface glucosaminoglycan, heparan sulfate.

This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.

This novel virulence trait, which increases severity of S. pneumoniae superinfection, involves pneumococcal surface protein A, now identified as an adhesin.

A comprehensive health-screening program in rural northern KwaZulu-Natal has found a high burden of undiagnosed or poorly controlled non-communicable diseases.

Knowledge of the specific flagellins that drive the pathogenic immune response in Crohn’s disease is a step toward a potential preventive treatment.

The list was made by a group that aspires to bolster and increase diversity across all scientific fields, promote retention through the “leaky academic pipeline,” and broaden academic and industrial awareness of diversity and inclusion.

Streptococcus pneumoniae is an opportunistic pathogen that commonly infects young children and the elderly. This atlas will help researchers better understand how to treat these infections.

The novel coronavirus can live on certain surfaces for up to two to three days.

Study points to a potential immediate treatment for this devastating disease.

IgA nephropathy is the leading primary glomerulonephritis worldwide.