Explore UAB

Bertha Hidalgo, Ph.D.
Bertha Hidalgo, Ph.D.

A recent study found that people of Mexican background are more likely to be at risk for Type 2 diabetes than other Hispanic/Latino background groups. The study, which was led by Bertha Hidalgo, Ph.D., a professor of epidemiology at the University of Alabama at Birmingham School of Public Health, examined variants — alterations to the DNA sequence — of the SLC16A11 gene in six different Hispanic and Latino background groups: Mexican, South American, Central American, Dominican, Puerto Rican and Cuban. The study was published in Scientific Reports.

The researchers analyzed data from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), which is a multicenter, community-based cohort study of Hispanic/Latino populations in the United States. The cohort collected data from approximately 16,000 people.

“Traditionally, large studies of Hispanic/Latinos have grouped several subgroups into a single category, ignoring the ancestral diversity that exists within this heterogenous population,” Hidalgo said. “The data from the Hispanic Community Health Study/Study of Latinos allows us to better understand the similarities and differences within and across these different subgroups.”

Previous studies have shown that variants of the SLC16A11 gene put people of Mexican descent at higher risk for developing Type 2 diabetes. However, this is the first study to look at the genetic risk in the other five subgroups.

While researchers confirmed the increased risk for the Mexican background group, they found there was not an increased risk in the South and Central American, Dominican, Puerto Rican, and Cuban background groups of HCHS/SOL.

Read More at https://www.uab.edu/news/research/item/10161-study-finds-gene-does-not-increase-risk-for-type-2-diabetes-in-all-hispanic-latino-background-groups-equally

Back to Top