Advanced special topics course in metabolomics 2017
(GBSC 724)
Course will be held on Mondays, Wednesdays and Fridays 1:30 pm to 3:00 pm in the SHELBY 515
Schedule
| Date | Lecturer | Topic |
|---|---|---|
| Jan 9, Mon | S. Barnes | Transition from metabolism to metabolomics and targeted/untargeted approaches [PDF File] |
| Jan 11, Wed | S. Barnes | The chemistry of the metabolome [PDF File] |
| Jan 13, Fri | S. Barnes | Gas- and liquid chromatography-mass spectrometry [PDF File] |
| Jan 16, Mon | Martin Luther King Holiday | |
| Jan 18, Wed | A. Patterson* | Extracting the metabolome (fluids, cells and tissues) [PDF File] |
| Jan 20, Fri | C. Petit | Fundamentals in NMR and metabolomics [PDF File] |
| Jan 23, Mon | X. Cui | Designing a complex –omics experiment [PDF File] |
| Jan 25, Wed | S. Barnes | The discovery of trimethylamine N-oxide [PDF File] [Reference 1] [Reference 2] |
| Jan 27, Fri | S. Barnes | Examining GC-/LC-MS data with Mzmine 2.21 [PDF File] |
| Jan 30, Mon | S. Barnes | Uploading GC-MS and LC-MS data to XCMSonline [PDF File] |
| Feb 1, Wed | P. Benton** | Development and developing functions of XCMS [PDF File] |
| Feb 3, Fri | First exam | |
| Feb 6, Mon | S. Barnes | Output of XCMS features for univariate analysis [PDF File] |
| Feb 8, Wed | X. Cui | Statistical analysis of XCMS data with MetaboAnalyst [PDF File] |
| Feb 10, Fri | S. Barnes | Pathway databases [PDF File] [Excel File] |
| Feb 13, Mon | S. Barnes | MS-DIAL software for data analysis [PDF File 1] [PDF File 2] |
| Feb 15, Wed | UNC-CH team | Processing NMR data [PDF File] [1. UAB_RFA_Metaboanalyst.csv] [2. UAB_RFA_Metaboanalyst_D14_NoPools.csv] [3. UAB_RFA_Metaboanalyst_D14_Vehicle_vs_HighDose.csv] |
| Feb 17, Fri | S. Barnes | The metabolomics workbench [PDF File] |
| Feb 20, Mon | Student presentations | |
| Feb 22, Wed | S. Barnes | Isotopically labeled precursors to identify pathways [PDF File] |
| Feb 24, Fri | J. Prasain | MSMS of small molecules - interpretation [PDF File] |
| Feb 27, Mon | J. Prasain | Validating metabolites [PDF File] |
| Mar 1, Wed | S. Barnes | Isotopes and pathway dynamics [PDF File] |
| Mar 3, Fri | Student presentations [Reference 1] [Reference 2] | |
| Mar 6, Mon | S. Barnes | Mummichog analysis of data [PDF File] |
| Mar 8, Wed | S. Barnes | SWATH-MS, Ion Mobility and LC-MS for lipidomics [PDF File] |
| Mar 10, Fri | J. Prasain | Lipid maps database [PDF File] |
| Mar 13, Mon | J Kabarowski | Lipid imaging-mass spectrometry [PDF File] [PPT File] |
| Mar15, Wed | A. Wende | Metabolomics in models of cardiovascular disease [PDF File] |
| Mar17, Fri | J. Prasain | Novel prostanoid molecules [PDF File] |
| Mar 20, Mon | H. Wu | The microbiome and metabolomics [PDF File] |
| Mar 22, Wed | C. Petit | NMR and magic angle spectroscopy [Reference 1] [Reference 2] |
| Mar 24, Fri | S. Barnes | In situ lipidomics in the surgical suite [PDF File] |
| Mar 27,Mon | Student presentations | |
| Mar 29, Wed | K. Uppal*** | Integrating the metabolome with the genome, transcriptome and proteome |
| Mar 31, Fri | FINAL exam due |
*Dr. Patterson is from Penn St University and will present his material by Skype
** Dr. Benton is from Scripps Res Inst, La Jolla and will present his material by Skype
*** Dr. Uppal is from Emory University and will present his material by Skype