RESEARCH
Impact Accerleration Tests & Material Properties of Rat BrainKurosh Darvish, Temple University & Jeff Crandall, University of Virginia |

- Characterization of the Kinematics of the Impact Acceleration Brain Injury Model
- Quantification of the Extent of Axonal Damage to the Brain Stem
- ••Determining the Brain Material Properties in Pre- and Post-trauma.
Data collected from the characterization of the kinematics of the impact acceleration test using rat brains is being used as the input to the rat brain Finite Element Model being developed by the Yang-King Team at Wayne State University.
Previous histological studies have shown that axonal damage to the brain stem occurs as a consequence of Impact Acceleration Tests. However, previous data are for a specific point in the brain stem. More information is needed on the spatial distribution of injury which could be used to determine the effect of injury on brain material properties, and to validate a finite element model of brain injury. The purpose of this objective is to develop the topography of axonal damage in the brain stem.

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