RESEARCH

Measuring Brain Tissue Injury Thresholds

Susan Margulies and David Meaney, University of Pennsylvania

As with other projects in the “Head-Brain Research Domain”, the Margulies-Meaney Team is also evaluating, enhancing, and improving the predictive capabilities of SIMon, with the ultimate goal of replacing the existing head injury criterion (HIC) as the regulatory standard for motor vehicle safety.

The Margulies-Meaney Team is involved in research designed to contribute to the development and subsequent validation of SIMon as a rigorous tool by generating the scientific foundation to be able to predict the probability of injury. Results are being sent to the Yang-King Team at Wayne State University and are being used as input in the validation of the SIMon models. This research includes 4 areas:

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Brain Injury Thresholds

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Brain Injury Geometry for a more sophisticated mesh development. This is important in determining how anatomically detailed a model must be to accurately predict whether or not brain injury will occur.

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