In addition to clinical trials to test new and investigational therapies, UAB researchers are also conducting studies designed to learn more about Alzheimer's disease, how it affects patients and families, and how to deliver the best care.  These studies do not involve investigational medicines.  Here are a few of the ongoing studies at UAB:

ThinkstockPhotos 85500585Cognitive Observation in Seniors (COINS) is led by Dr. Dan Marson, an expert in financial capacity, and is funded by the NIH (R01AG021927). The COINS study is determining how functional capacity, especially the ability to handle finances, changes in the early stages of Alzheimer's disease. This study is not currently recruiting.

The Applying Programs to Preserve Skills (APPS) study is led by Dr. Virginia Wadley Bradley and funded by the NIH (R01AG045154).  This study is investigating methods to improve processing speed in patients with mild cognitive impairment (MCI) to try to preserve functional ability. For more information, click here.

Rita Jablonski-Jaudon, PhD, RN, leads an NIH-funded study of care-resistant behaviors in patients with dementia (R01NR012737).  The study has helped develop new methods to improve mouth care and oral hygeine in nursing home residents with dementia. This study is not currently recruiting.

The Clinical Correlates of Family Quality of Life in Dementia (FAQs) study is led by Dr. Marissa Natelson Love.  This study designed to examine how dementia affects family quality of life. For more information click here.

The Early Warning Signs of Impaired Financial Skills in Older Adults study is led by Dr. Marson and is funded by the National Endowment for Financial Education (NEFE) and also supported by the National Institute on Aging. This study has analyzed existing clinical datasets at UAB and identified very early warning signs of financial skill decline in cognitively normal older adults later destined to undergo
cognitive decline. This study is not recruiting. For more information click here.

Dr. David Geldmacher is leading a project focused on using patient-specific genetic information to select medications to help attenuate behavioral and psychiatric symptoms in patients with dementia who receive care at the UAB Memory Disorders Clinics.  Working in collaboration with UAB's Hugh Kaul Personalized Medicine Institute, the goal of the project is to investigate the possibility of basing medication selection in part on information about an individual's genetic tendencies to respond to certain drugs.