The Bedwell lab seeks to understand the mechanistic details of translation termination in eukaryotes, and to use that knowledge to develop therapeutic strategies for a range of genetic diseases caused by premature translation termination mutations (PTCs). 

The Cingolani lab uses biophysical, biochemical, and cellular techniques to study the structure and function of biological macromolecules. We employ rigorous chemical and physical methodologies to solve medically relevant problems that help to decipher the most fundamental mechanisms of life and contribute to improving human health. Dr. Cingolani serves as the Director of UAB Center for Integrative Structural Biology (iSB).

The Du lab researches the treatment of genetic diseases caused by premature termination codons (PTCs).

The goal of the Collaborative Bioinformatics Research Lab is to provide high-quality modern Bioinformatics research solutions for data analyses, workflow development and consultations.

The Gupta lab focuses on identifying new molecules and pathways and studying their role in tumor initiation and progression. 

Professor
Departmental Wellness Champion

Research Interests: Biosynthesis of retinoic acid

The Keeling lab seeks to better understand these PTC-mediated mechanisms in order to develop therapies that can overcome the consequences of PTCs on gene expression.

The Renfrow lab makes use of high resolution Fourier transform mass spectrometry (FT-MS) to analyze the clustered O-glycans found on the immunoglobulin IgA1 as related to the pathogenesis of IgA nephropathy.

The Rizzardi lab research involves understanding how genetic variation influences cellular function through altered gene regulation in specific cell types in the brain.

The Schneider lab works to discover fundamental mechanisms by which eukaryotic cells control gene expression.

The Wang lab is committed to providing individualized training plans to support each trainee in reaching their full potential in biomedical research.