Displaying items by tag: department of biomedical engineering

Basic and translational research in this field aims to repair heart injury and prevent the heart failure that often follows a heart attack.

Preclinical experiments show how to identify non-responding tumors and improve their response to immunotherapy, using two investigational new drugs that are permitted for human use. Physicians could immediately start investigational research in patients to test the effectiveness of this personalized approach.

Release of TT-10 from nanoparticles improved heart function after a heart attack, accompanied by increased cardiomyocyte proliferation and smaller infarct size.

Researchers used a pig model of heart attacks, which more closely resembles the human heart in size and physiology, and thus has high clinical relevance to human disease.
The virtual symposium will cover topics such as gene editing and cardiac stem cells in heart failure and feature the National Academy of Medicine president as a keynote speaker.
The exosomes were secreted by cardiac cells derived from human induced pluripotent stem cells. These non-living exosomes may be an easier form of regenerative treatment than living cells.
Injections of two chemicals in a slow-release form significantly reduced the size of dead heart tissue and improved the function of the left ventricle.

Educational and economic opportunities in central Alabama are enhanced by new microscope available for research.  

This regenerative potential is lost within days after birth, which is why adult heart attacks lead to heart failure.
This method — tested in a mouse heart attack model — doubled the engraftment rate of injected stem cell-derived cardiomyocytes.
Three UAB Innovation Fellows answer questions about their trip to a Dubai conference in April — from learning experiences to future adjustments and ideas.
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