Displaying items by tag: department of pathology

This study, performed in a pre-clinical human model, is the first time xenotransplanted pig kidneys have shown clearance of creatinine and shown a standard immunosuppression regimen may be sufficient.
Some PD-1+CXCR5+CD4+ T cells will become germinal center-Tfh cells that are essential for B cells to become high-affinity antibody-producing cells. Others do not take that path, instead becoming memory T cells.
In a mouse model, border-associated macrophages, not microglia, were essential for the neuroinflammation that precedes neurodegradation. Targeting this subset could be a disease-modifying therapy in neurodegenerative disease.
This funding will be used to research multiple health conditions, including alcohol-related liver disease, Alzheimer’s disease, breast cancer, heart failure, inflammatory bowel disease and Zhu-Tokita-Takenouchi-Kim syndrome.
Suits for Success’ impact transcends to three other UAB closets and a community closet serving students, patients and underprivileged women facing domestic violence.
UAB is joining the Red Cross in encouraging the public to donate blood now.
Description of this mechanism offers a promising therapeutic target to limit lung injury and death. Lower respiratory tract infections, including bacterial pneumonia, are the fourth-leading cause of death worldwide, with 120 million to 156 million cases and 1.4 million deaths a year.
President Ray L. Watts, M.D., and Anupam Agarwal, M.D., dean of the Heersink School of Medicine, invite you to the Distinguished Faculty Lecture honoring Casey Weaver, M.D., recipient of the 2022-2023 Distinguished Faculty Lecturer Award.
Mechanistic findings in this study may pave the way for future time-restricted feeding studies in muscle, providing a natural and affordable form of alternative therapy for managing pathologies related to metabolism and obesity.
The researcher says this proposal will analyze the novel concept that circadian disruption presents an additional challenge to mitochondrial function and liver health in the alcohol consumer.
Insights that are not possible with conventional two-dimensional platforms include characterization of obliterated airways in tuberculosis and hemorrhage from ruptured blood vessels in COVID-19 lungs, at near-microscopic levels.
Experiments reveal that a catalytic subunit of CK2, called CK2α, is an important regulator of mouse CD8+ T cell activation, metabolic reprogramming and differentiation, both in vitro and in a mouse-infection model by the intracellular pathogen Listeria monocytogenes.
The funding will be used to purchase cutting-edge equipment to assist with high-containment research productivity and pandemic preparedness at UAB.
The funding from the Norma Livingston Ovarian Cancer Foundation will help further ovarian cancer research to advance therapeutic treatments.
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