Forms: Download Registration Form
Held On: November 29-30, 2007
Location:
The King and Prince Beach &AMp; Golf Resort
201 Arnold Rd.
St. Simons Island, GA 31522

Organizing Committee:

Overview

Caloric restriction (CR) retards aging in many species. Obesity increases the mortality rate in humans. Yet beyond this superficial commonality, the connections between these two phenomena are incompletely known. So too, the mechanisms behind obesity’s deleterious and CR’s salubrious effects are minimally known and almost certainly manifold. Access to several emerging resources offers the opportunity to address new questions about the extent to which reduced energy intake, negative energy balance, lower body weight, reduced body fat, reduced body fat in specific depots, the dynAMic process of weight or fat loss, or even hunger itself play roles in influencing longevity. This meeting will assemble a diverse highly-interdisciplinary group of investigators to address these issues.

Women, members of underrepresented minority groups and individuals with disabilities are strongly encouraged to apply.

Registration is $200 for attendees from academic, government, and not-for-profit organizations and $850 for attendees from for-profit companies and does not include the cost of food, travel or lodging. Limited funds are available on a competitive basis for travel scholarships with preference given to graduate students and post-doctoral fellows.

Registration will be limited, so please apply prior to Fri 9/28/2007. Accepted applicants will be notified by Mon 10/1/2007.

Schedule of Events

DateTimeSpeaker/ModeratorTopicVideo
Nov 29, 2007 8:00 AM-8:05 AM David B. Allison, Ph.D.
University of Alabama at Birmingham
Announcements/Business  
I. Epidemiologic Puzzles &AMp; Novel Statistical Approaches
JoAnn Manson, M.D., Dr.P.H
Harvard University
Overview by Moderator    
8:10 AM-8:45 AM June Stevens, Ph.D.
University of North Carolina, Chapel Hill
Obesity &AMp; Mortality Rate in Humans: Evaluating the impact of age and ethnicity Watch Video
8:45 AM-9:20 AM Eugenia Calle, Ph.D.
American Cancer Society
Obesity &AMp; Mortality Rate in Humans: Are the effects changing with calendar time?  
9:20 AM-9:55 AM David B. Allison, Ph.D.
University of Alabama at Birmingham
Statistical approaches to modeling the latent confounding variables and incorporating information from experimental and clinical domains Watch Video
9:55 AM-10:25 AM All speakers led by Moderator Panel Discussion Watch Video
10:25 AM-10:35 AM Break
II. Role of Body Composition
10:35 a.m -10:40 AM Leanne M. Redman, Ph.D.
Pennington Biomedical Research Center
Overview by Moderator  
10:40 AM-11:15 AM Tim R. Nagy, Ph.D.
University of Alabama at Birmingham
Ambient temperature manipulation and in vivo body composition measurements to separate the effects of adiposity and energy intake on longevity Watch Video
11:15 AM-11:50 AM Nir Barzilai, M.D.
Albert Einstein College of Medicine
The role of selective fat depletion in life-prolongation in rodents Watch Video
11:50 AM-12:25 PM Heidi Tissenbaum, Ph.D
University of Massachusetts, Worcester
Role of body fat in longevity Watch Video
12:25 PM-12:55 PM All speakers led by Moderator Panel Discussion Watch Video
12:55 PM-2:00 PM Lunch
Nov 29, 2007 III. Role of Hunger
2:00 p.m -2:05 PM Blanka Rogina, Ph.D.
University of Connecticut Health Center
Overview by Moderator Watch Video
2:05 p.m -2:40 PM Charles Mobbs, Ph.D.
Mount Sinai School of Medicine
HypothalAMic mechanisms in caloric restriction and aging Watch Video
2:40 p.m -3:15 PM R. Michael Anson, Ph.D.
Community College of Baltimore County
Could Hunger be the key hormetic signal? Watch Video
3:15 p.m -3:25 PM Break
3:25 p.m -4:00 PM William Donahoo, M.D.
Kaiser Foundation Research Institute
Beneficial Metabolic Effects of Fasting Watch Video
4:00 p.m -4:35 p.m James Waddle, Ph.D.
Southern Methodist University.
Longevity mediated by fasting-induced changes in chromatin composition Watch Video
4:35 p.m -5:05 PM All speakers led by Moderator Panel Discussion Watch Video
Nov 30, 2007 8:00 AM-8:05 AM David B. Allison, Ph.D.
University of Alabama at Birmingham
Announcements/Business  
IV. What We Have and Can Learn from Clinical Studies
8:05 AM-8:10 AM Julie Mattison, Ph.D.
National Institute on Aging
Overview by Moderator  
8:10 AM-8:45 AM Eric Ravussin, Ph.D.
Pennington Biomedical Research Center
Results from early human studies Watch Video
8:45 AM-9:20 AM Luigi Fontana, M.D., Ph.D.
Washington University in St.Louis &AMp;
Italian National Institute of Health
Long-term metabolic effects of calorie restriction in humans  
9:20 AM-9:55 AM Ted Adams Ph.D., MPH
University of Utah
Effects of surgically-induced weight loss in humans Watch Video
9:55 AM-10:25 AM All speakers led by Moderator Panel Discussion Watch Video
10:25 AM-10:35 AM Break
V. Role of Energy Expenditure, Exercise, and Negative Energy Balance
10:35 AM-10:40 AM Ramon Darazu-Arvizu, Ph.D.
Loyola University, Chicago
Overview by Moderator  
10:40 AM-11:15 AM Theodore Garland Jr., Ph.D.
University of California, Riverside
Effects of Selective Breeding for High Voluntary Activity Levels in House Mice on Energy Balance and Longevity Watch Video
11:15 AM-11:50 PM Tamara Harris, M.D.
National Institute on Aging
Strength, exercise, muscle mass, muscle function, and longevity  
11:50 PM-12:25 PM Susan Ozanne, Ph.D.
University of Cambridge
The role of rapid catch-up growth or intense positive energy balance in early life Watch Video
11:50 PM-12:25 PM All speakers led by Moderator Panel Discussion Watch Video
12:25 PM-2:00 PM Lunch
Nov 30, 2007
VI. What We Have and Can Learn from Non-Human Primates
2:00 PM-2:05 PM Catherine A. Wolkow, Ph.D.
National Institute on Aging
Overview by Moderator  
2:05 PM-2:40 PM Richard Weindruch, Ph.D.
University of Wisconsin at Madison
Results from the Wisconsin CR Study  
2:40 PM-3:15 PM Donald Ingram, Ph.D.
Louisiana State University System
Results from the NIA CR Study Watch Video
3:15 PM-3:25 PM Break
3:25 PM-4:00 PM Barbara C. Hansen, Ph.D., University of South Florida Results from a primate model of obesity and CR: middle-aged weight gain prevention Watch Video
4:00 PM-4:35 PM George Roth, Ph.D.
Geotech
Caloric Restriction Mimetics: The Newest Anti-aging Strategy Watch Video
4:35 PM-5:05 PM All speakers led by Moderator Panel Discussion Watch Video

Speakers

  • David B. Allison, Ph.D., UAB
  • Tim R. Nagy, Ph.D., UAB
  • Ted Adams, Ph.D. MPH, University of Utah
  • R. Michael Anson, Ph.D., Comm College Baltimore
  • Nir Barzilai, MD, A Einstein College Med
  • Eugenia Calle, Ph.D., American Cancer Society
  • William Donahoo, MD, Kaiser Permanente
  • Ramon Durazo-Arvizu, Ph.D., Loyola University, Chicago
  • Luigi Fontana MD, Ph.D., Washington University in St. Louis & Italian National Institute of Health
  • Barbara C. Hansen, Ph.D., University of South Florida
  • Tamara Harris, MD, National Institute on Aging
  • Donald Ingram, Ph.D., Louisiana State University System
  • Theodore Garland Jr., Ph.D., University of California, Riverside
  • JoAnn Manson, MD DrPH, Harvard Medical School
  • Julie Mattison, Ph.D., National Institute on Aging
  • Charles Mobbs, Ph.D., Mount Sinai School Med
  • Catherine A. Wolkow, Ph.D., National Institute on Aging
  • Susan Ozanne, Ph.D., University of Cambridge
  • Eric Ravussin, Ph.D., Pennington Biomedical Research Center
  • Blanka Rogina, Ph.D., University of Connecticut Health Center
  • George Roth, Ph.D., Geotech
  • June Stevens, Ph.D., University of North Carolina, Chapel Hill
  • Heidi Tissenbaum, Ph.D., University of Massachusetts, Worcester
  • James Waddle, Ph.D., Southern Methodist University
  • Richard Weindruch, Ph.D., University of Wisconsin at Madison
  • Leanne M. Redman, Ph.D., Pennington Biomedical Research Center

Contact Information:

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Sponsors:
Clinical Nutrition Research Center,
University of Alabama at Birmingham

Funding for this conference was made possible (in part) by (1R13AG030317-01) from the National Institute on Aging (NIA). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention by trade names, commercial practices, or organizations imply endorsement by the U.S Government.