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Held On: February 15, 2008
Location: Learning Resources Center, Room 102
University of Alabama at Birmingham Campus

Primary Sponsors:


  • Arthritis and Musculoskeletal Diseases Center
  • Center for AIDS Research
  • Center for Free Radical Biology
  • Center for Metabolic Bone Disease
  • Center for Women's Reproductive Health
  • Civitan International Research Center
  • Comprehensive Cancer Center


Jose R. Fernandez, Ph.D.
Associate Professor, Department of Nutrition Sciences
University of Alabama at Birmingham

David B. Allison, Ph.D.
Director, Clinical Nutrition Research Center
Professor, Departments of Biostatistics and Nutrition Sciences
University of Alabama at Birmingham

Donna K. Arnett, Ph.D.
Professor and Chair, Department of Epidemiology
University of Alabama at Birmingham

Jan P. Dumanski, Ph.D.
Professor, Department of Genetics
Director, Howell and Elizabeth Heflin Center for Human Genetics
Senior Scientist, Comprehensive Cancer Center
University of Alabama at Birmingham


Advances in molecular biology continue to move the field of genetics to new horizons. No longer are we only concerned with SNP or microsatellite variation in nuclear DNA. A range of promising new technologies allows scanning of the entire human genome for new types of variations with accuracy and efficiency. The extent to which new technologies can be used to identify the molecular basis of trait variation and disease risk is a topic of interest among UAB scientists and researchers who wish to work at the frontier of genetic science. This program is meant to introduce some of these new technologies. Morning sessions will consist of scientific overviews by outstanding internationally recognized speakers. These presentations will emphasize what can be done. Afternoon sessions will consist of presentations that emphasize at a very practical level how to get the job done.

Distinguished Speakers

Charles Lee, Ph.D.
Director of Cytogenetics, Harvard Cancer Center
Assistant Professor, Harvard Medical School

Carmen Sapienza, Ph.D.
Professor, Department of Pathology
Associate Director, Fels Institute for Cancer Research and Molecular Biology
Temple University

Joseph Costello, Ph.D.
Associate Professor, Department of Neurological Surgery
University of California San Francisco

Carlo M. Croce, M.D.
Director, Institute of Genetics
Chair Molecular Virology, Immunology & Medical Genetics
Ohio State University


8:00-8:20 AM Registration/Breakfast  
8:20-8:30 AM Welcome Remarks David B Allison, Donna Arnett, & Jose Fernandez Watch Video
8:30-9:15 AM Structural Genomic Variation and Human Health Charles Lee, Ph.D. Watch Video
9:15-10:00 AM Causes and Consequences of Epigenetic Variation in the Human Population Carmen Sapienza, Ph.D. Watch Video
10:00-10:30 AM BREAK  
10:30-11:30 AM Techniques for DNA Methylation Profiling and Their Application to Comparative Epigenomics Joseph Costello, Ph.D. Watch Video
11:30-12:00 PM Role of MicroRNAs in Human Cancer Carlo M Croce, MD Watch Video
12:00-1:30 PM LUNCH    
1:30-2:15 PM Somatic Mosaicism for CNVs; Analysis of Monozygotic Twins and Differentiated Human Tissues, and Practical Aspects of Assessing Copy Number Variation Jan Dumanski, Ph.D. Watch Video
2:15-3:00 PM Practical Aspects of Studying MicroRNA Carlo M Croce, M.D.  
3:00-3:30 PM Practical Aspects of Assessing Genomewide Methylation/Epigenetics Carmen Sapienza, Ph.D.