• Funded P/F Projects for 2021

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Sonia Fargue
    (Named New Investigator)
    Urology Role of Obesity on Endogenous Oxalate Synthesis
    Mary Latimer Medicine- Cardiovascular Disease NFIL3 is a Novel Target Against Obesity-induced Inflammation and Co-morbidities
    Anna Thalacker-Mercer Cell, Development, & Integrative Biology Essentiality of Serine and Glycine for Skeletal Muscle Regeneration
  • Funded P/F Projects for 2020

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Glenn Rowe
    (Named New Investigator)
    Medicine The role of the syndecan-4/heparanase axis in exercise induced angiogenesis in white adipose tissue
    Michael Behring Pathology Identify a role for TP53 polymorphism in obesity-related colorectal cancer
    Susan Bellis Cell, Developmental, and Integrated Biology Role of novel glycosylation-mediated pathway in promoting obesity
    Andrew Hardaway Psychiatry Characterization of the hindbrain to amygdala Glucagon-like peptide-1 system
  • Funded P/F Projects for 2019

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Drew Sayer, Ph.D., Assistant Professor
    (Named New Investigator)
    Nutrition Sciences Effects of Dietary Protein Intake and Resistance Training on Retention of Fat Free Mass during Weight Loss in Postmenopausal Women with Obesity
    Sara Deemer, Ph.D., Postdoc NORC The Influence of a Hypocaloric Low-Carbohydrate or Low-Fat Diet on Adipose Tissue Remodeling and Gene Expression in Obese African American Women
    Stephanie Silveira, Ph.D., Postdoc Physical Therapy Feasibility, acceptability and validity of self-report, model-predicted, and biologically measured energy intake in adults with multiple sclerosis
    Bhuvana Sunil, M.D., Fellow Endocrinology Effect of carbohydrate restricted versus standard low fat diet in the treatment of dyslipidemia in children with metabolic syndrome
    William Turbitt, Ph.D., Postdoc NORC Reversing obesity-associated immunotherapy failure in renal cancer through time-restricted feeding
  • Funded P/F Projects for 2018

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Brooks Wingo
    (Named New Investigator)
    Occupational Therapy Comprehensive Lifestyle Intervention for Reducing Cardiometabolic Risk and Symptom Burden in Adults with Multiple Sclerosis.
    Kyle Wood Urology Role of Obesity and Fatty Liver in Kidney Stone Disease.
  • Funded P/F Projects for 2017

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Gowey, Marissa
    (Named New Investigator)
    Pediatrics Using executive function to predict outcomes and adherence in family-based behavioral weight management.
    Li, Yuanyuan Biology The epigenetic effects of maternal bioactive dietary compound on transgenerational weight control: a new approach to early obesity interference.
    Speed, Joshua Nephrology Dietary Sodium, Obesity, and Insulin Resistance: Role of Endothelin-1.
    Wood, Kyle Urology Role of Obesity and Fatty Liver in Kidney Stone Disease.
  • Funded P/F Projects for 2016

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Eric Plaisance
    (Named New Investigator)
    Human Studies Role of Hydroxycarboxylic Acid Receptor Agonists on Energy Homeostasis and Metabolism
    Margaux Barnes Pediatrics Mediational Analysis of Diet Composition, Physical Activity, and Lean Mass in Pediatric Patients with IBD
    Laura Dreer Opthamology Examination of Obesity, Nutrition/Dietary Intake, Physical Activity, and Lifestyle Behaviors Among People with Vision Impairments: Implications for Development of a Weight Management Behavioral Health Program
    Shahid Mukhtar Biology Elucidating the Molecular Mechanisms of DBP, a Component of Circadian Clock, in Obesity Using Zebrafish Model
  • Funded P/F Projects for 2015

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Nicole Riddle
    (Named New Investigator)
    Biology Variation in the response to exercise - is there an epigentic component?
    Aaron Fabian Child & Adolescent Psychology A Sleep and Media Use Intervention to Improve Adolescents' Weight and Risk of Type 2 Diabetes
    Anupam Agarwal Nephrology Role of Heavy Chain Ferritin in the Onset of Obesity
  • Funded P/F Projects for 2014

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Julia Gohlke Environmental Health Science Evolutionarily conserved pathways, lipid storage and life span in Daphnia pulex on varied diets and exposed early in life to methyl mercury
    Tapan Mehta
    (Named New Investigator)
    Physical Therapy Have the Advances in Cardiometabolic Treatments Attenuated the Obesity-Mortality Association?
    Peggy Biga Biology Amino acids, methionine specifically, regulate myogenic progression via tight epigenetic mechasnims of myognic regulating genes in indeterminate growth
  • Funded P/F Projects for 2013

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Paula Chandler-Laney (2nd Year) Nutrition Sciences Does infant feeding behavior mediate the association between maternal metabolic health during pregnancy and infant gain in adiposity?
    Peggy Biga
    (Co-Named New Investigator)
    Biology Role of amino acids in the epigenetic regulation of muscle growth in determinate and indeterminate growth paradigms
    Emily Dhurandhar
    (Co-Named New Investigator)
    Health Behavior Subjective Social Status as a Determinant of Fat Accretion in Response to Weight Gain
    Li Li Psychology Early life origins of obesity: the relationship between early life stress and abdominal obesity in depressed patients
    Kasturi Mitra Genetics Interactions between dietary components driven Insulin signaling and mitochondrial fission machinery in Drosophila ovaries: a novel approach to understand insulin related metabolic diseases
  • Funded P/F Projects for 2012

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Paula Chandler-Laney
    (Named New investigator)
    Nutrition Sciences The use of a jaw motion sensor to objectively measure infant feeding behavior
    Balu Chacko Molecular & Cellular Pathology Obesity and bioenergetic dysfunction in human subjects
    Karen Gamble Psych - Behavioral Neurobiology Role of glycogen synthase kinase 3 in daily energy balance
    Ana Vazquez Biostatistics Statistical Methods for Multivariate Genome Wide SNPs: Developments for Obesity, Body Composition and Bone Health
  • Funded P/F Projects for 2011

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Degui Zhi Biostatistics Expression of ribosomal protein genes and pseudogenes in adipose and its implications to obesity (Renewal)
    Ching-Yi Chen Biochemistry & Molecular Genetics (JHS) Function of KH-type Splicing Regulatory Protein (KSRP) in Control of Circadian Clock and Adiposity
    Anna Thalacker-Mercer
    (Named New investigator)
    Physiology & Biophysics (JHS) Peptide YY regulation of inflammatory signaling in primary skeletal muscle cells
    Inga Kadisha Cell Biology (JHS) Effect of dietary composition on the development of Alzheimer's Disease
  • Funded P/F Projects for 2010

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Gustavo de los Campos Biostatistics Identification and Quantification of Genetic Factors Affecting the Effect of BMI as a Risk Factor for Relevant Human Diseases and Mortality
    Jong-Eun Kim (NNI) Mechanical Engineering Childhood obesity as a risk factor for traumatic injuries: A mechanistic study
    Christine Duarte Biostatistics Statistical model development with applications to genetic research in obesity-related traits
    Dorothy Pekmezi Epidemiology Piloting the use of accelerometers and a culturally-adapted, computer tailored physical activity intervention for African Americans
    Daniel Smith Nutrition Sciences Diet and husbandry optimized for growth and reproduction in zebrafish (Danio rerio) as a predictor of reduced health and longevity
    Degui Zhi Biostatistics Differential gene expression of ribosomal proteins and its implication to obesity
  • Funded P/F Projects for 2009

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Mickie Powell Biology The Relationship of Dietary Polyunsaturated Fatty Acids (Omega 6 and Omega 3) to Inflammation in Zebrafish (Danio rerio)
    Xujing Wang Physics Joint mathematical and biological investigation of glucose tolerance
    Michael Miller Cell Biology Role of Secreted VAP MSP Domains in Insulin/FOXO Signaling and Fat Metabolism
    Andries Steyn Microbiology Nitrite-based therapy for targeting dormant mycobacterium tuberculosis
    Olivia Thomas Affuso (NNI) Epidemiology Critical periods of exercise in childhood
  • Funded P/F Projects for 2008

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Kristine Lokken and Heather Austin Psychology Decision Making, Problem Solving and Impulsivity in Obese Adolescents
    Xuxia Wu (NNI) Nutrition Sciences Regulation of Macrophage Infiltration and Foam Cell Formation in Obesity
    Robert Kesterson Genetics Temporal Regulation of Muscle Mass and Regeneration via Conditional Expression of a Dominant Negative Myostatin (GDF-8) Transgene
    Alexander Salai Medicine CRP-Mediated Maintenance of Homeostasis
  • Funded P/F Projects for 2007

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Steven Lloyd (NNI) Medicine Effect of a Low-carbohydrate Diet on Myocardial Energy Substrate Utilization and Response to Myocardial Ischemia
    Pia Sen Health Care Organization What Do People In Different Income Groups Buy When They Do Not Buy Fruits and Vegetables?
    Kristine Lokken and Heather Austin Psychology Decision Making, Problem Solving, and Impulsivity in Obese Adolescents
    Rex Wright Psychology Obesity and Effort-Related Cardiovascular Response to Performance Challenge
    Andrea Cherrington Medicine Culturally Adapting a Proven Weight Loss Intervention to Reduce Diabetes Risk in Latina Immigrants
    Nefertiti Durantn Pediatrics Efficacy of moderate intensity exercise in promotion of weight loss and prevention of weight gain in young African American women
  • Funded P/F Projects for 2006

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    John Hartman Genetics Buffering DNA Replication by Regulation of Threonine Metabolic Flux
    Steven Lloyd Genetics The Effect of Low Carbohydrate Diet on Myocardial Energy Substrate Utilization and Response to Myocardial Ischemia
    Murat Tanik Electrical and computer engineering Intelligent Information Integration and Retrieval (I3R) System for Scientific Research and Analysis
    Edmund Kabagambe Epidemiology Diet, Genetic Polymorphisms in Lipid-Metabolizing Enzymes and Antiretroviral Therapy-Related Dyslipidemia: A Pilot Study
    Patrick Ramsey Ob/gyn Relationship of Maternal Obesity with Plasma Folate Levels and Response to Folic Acid Supplementation
  • Funded P/F Projects for 2005

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    John Hartman Genetics Buffering DNA Replication by Regulation of Threonine Metabolic Flux
    Bradley Yoder Cell Biology Cilia Function and Regulation of Energy Homeostasis
    Yingkui Yang Pediatric Surgery The Molecular Determinants of Human Melanocortin-3 Receptor Responsible for Ligand Binding
    Yao Huang Med- Endocrinology, Diabetes & Metabolism Insulin-like Growth Factor-1 (IGF-1) and Growth Hormone (GH) Signaling in Pancreatic Islet B-Cells
    Xiangqin Cui Biostatistics Characterizing the Diet/Nutrition Effect on Gene Alternative Transcripts Using Affymetrix Microarray Data

    Projects Funded for Second Year:

    Primary InvestigatorDepartmentTopic
    Jamy Ard Nutrition Sciences Long-term Follow Up of EatRight Weight Management Program Participants
    Shannon Bailey Environmental Health Sciences Mitochondrial dysfunction and NASH
    Monica Baskin Health Behavior A Family-Based Intervention for African American Children at Risk for Overweight and Obesity
  • Funded P/F Projects for 2004

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Jamy Ard Nutrition Sciences Long-term Follow Up of EatRight Weight Management Program Participants
    Shannon Bailey Environmental Health Sciences Mitochondrial dysfunction and NASH
    Monica Baskin Health Behavior A Family-Based Intervention for African American Children at Risk for Overweight and Obesity

    Projects Funded for Second Year:

    Primary InvestigatorDepartmentTopic
    Paul Wolkowicz Medicine Role of fatty acid oxidation in regulating leptin expression
    Nengjun Yi
    (Named New Investigator)
    Biostatistics Mapping complex epistatic genes for obesity in experimental designs
  • Funded P/F Projects for 2003

    Newly Funded Projects:

    Primary InvestigatorDepartmentTopic
    Nengjun Yi Biostatistics Mapping complex epistatic genes for obesity in experimental designs.
    Ying-Kui Yang
    (New Named Investigator)
    Surgery The molecular determinants of human melanocortin-3 receptor responsible for ligand binding.
    Paul Wolkowicz Medicine Role of fatty acid oxidation in regulating leptin expression.

    Projects Funded for Second Year:

    Primary InvestigatorDepartmentTopic
    Jose Fernandez Nutrition Sciences Genetic admixture in physical activity in African- and European-American women.
    Mark Garfinkel Environmental Sciences Drosophila model of genetic variations governing fat body mass and obesity.
  • Funded P/F Projects for 2002
    • Jose Fernandez, Ph.D.
      Genetic Admixture in Physical Activity in African- and European- American Women
    • Mark Garfinkel, Ph.D.
      Drosophila Model of Genetic Variations Governing Fat Body Mass and Obesity
    • Mary Hagan, Ph.D. (2nd year funding)
      The Role of Agouti-Related Peptide (AgRP) in Diet-Induced Obesity
    • Chandrika Piyathilake, PhD (2nd year funding)
      The Cancer Protective Effect of Fruit and Vegetable Intake: Modification by Genetic Susceptibility Factors
  • Funded P/F Projects for 2001
    • Paul Brookes, Ph.D.
      Post-Transcriptional Regulation of Mitochondrial Uncoupling Proteins
    • Barbara Gower, Ph.D. (2nd year funding)
      Metabolic Effects of Estrogen and Progesterone
    • Mary Hagan, Ph.D.
      The Role of Agouti-Related Peptide (AgRP) in Diet-Induced Obesity
    • Chandrika Piyathilake, Ph.D.
      The Cancer Protective Effect of Fruit and Vegetable Intake: Modification by Genetic Susceptibility Factors
    • Roger White, Ph.D.
      Loss of Estrogenic Function in Obese Zucker Rats
    • Michael Wyss, Ph.D. (2nd year funding)
      Neural Control of Ingestive Behavior
  • Funded P/F Projects for 2000
    • Barbara Gower, Ph.D.
      Ovarian Hormones and Energy Expenditure
    • Eric Knochenhauer, Ph.D.
      Impact of Dietary Fat on Hyperandrogenism
    • Michael Wyss, Ph.D.
      Neural Control of Ingestive Behavior
    • Bradley Newcomer, Ph.D. (2nd year funding)
      Intramuscular Lipid Redistribution in AIDS