The George M. O’Brien Kidney Resource Alliance (OKRA) is supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
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The George M. O’Brien Kidney Resource Alliance (OKRA) is a consortium of National Resource Centers (NRCs) whose primary purpose is to provide kidney researchers with specialized resources, tools, technologies, services, and expertise beyond those typically available in an individual lab or institutional core.
The next session of the OKRA National Forum is coming up! Join us on Thursday, December 18 from 10-11am CST / 11am-12pm EST to hear Dr. Laura Schwartz (Nationwide Children's Hospital and The Ohio State University) present on “Insulin receptor and intercalated cell innate immunity”
Be sure to check out the OKRA consortium’s publications! Indiana University’s recent article discusses interrogating human kidney biopsies with integrated spatial protein imaging and spatial transcriptomics. This work identifies the Thy1 gene and protein expression as an important marker of healthy proximal tubules that undergoes dynamic changes with kidney disease. It is therefore a novel biomarker and potential therapeutic target.
The OKRA NCC is proud to highlight the recent efforts of Arnold Davis! Arnold serves on the OKRA Patient Advocacy Council (PAC) and devotes his time to improving outreach, advocacy, and education throughout the kidney community. You can read his recent interview with ASN’s KidneyNews Online HERE.
Learn more about WashU’s recently published article, “Multimodal spatial transcriptomic characterization of mouse kidney injury and repair.” This article discusses multiscale spatial mapping of over one million kidney cells, revealing a critical fibro-inflammatory niche and cell-cell communication network that drives the progression from acute kidney injury to chronic kidney disease. All code with detailed tutorials is publicly available for all analyses, including multimodal integration.
Read the full article HERE and access GitHub code tutorials HERE.
Missed a recent OKRA presentation? Watch the recording on our Kaltura channel! We’ll be posting past National Forums and Gumbo Gatherings so you can learn more about all the O’Brien Kidney Resource Alliance offers.
There are many funding opportunities for researchers at every stage of their career! Make sure to check out the list of upcoming opportunities on our website. Regularly updated, this list includes the NIA 2025 Start-Up Challenge and Accelerator, the NIH’s Kidney Technology Development Research Education Program, and supplements to promote diversity in small business research and development.
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