NU-USC George M. O’Brien Kidney Resource Center
The Northwestern University–University of Southern California O’Brien Kidney Resource Center supports kidney research by integrating innovations from the physical sciences, including nanotechnology, proteomics, and other emerging technologies, into studies of kidney disease. Through its Resource Development Core, the Center develops innovative research methodologies, advanced technologies, and specialized resources and makes them available to investigators through the Biomedical Resource Core, fostering scientific collaboration and innovation in kidney research.
Biomedical Resource Core (BRC)
The BRC provides investigators with access to nanoparticle-based drug delivery technologies for kidney research, along with expertise in the formulation and characterization of nanoparticle delivery platforms, including micelles. These platforms can be engineered to deliver therapeutic cargos such as peptides, small-molecule drugs, and short RNAs, including siRNA and microRNA. The BRC also develops kidney-targeting approaches using targeting peptides and optimized formulations to enhance delivery to the kidney and specific renal cell populations. In addition, the BRC provides established genetically engineered mouse lines, including Cre-driver lines, enabling investigators to conduct cell-type-specific studies. The BRC offers consultation on in vitro and in vivo study design for therapeutic evaluation and supports the development of grant applications and scientific publications.
Contact Information
For more information about the services provided by the NU-USC O’Brien Kidney Resource Center, including associated fee structures, please contact:
For nanotechnology applications and Biomedical Resource Core inquiries:
Yunxi Chen, PhD
yc_452@usc.edu
For mouse lines and general Center inquiries:
NU-USC Team
nephrohub@northwestern.edu