We are looking for volunteers to participate in a clinical study to advance lupus treatment.If you are interested in seeing if you may qualify for an ongoing clinical study, please contact Christina Ndolo at cmndolo@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

If you are currently taking antidepressant medications but still struggle with depression, you may qualify for a new clinical research study. The study is evaluating an oral investigational medication for depression that can be taken with your current antidepressant medication. For more information and to see if you're eligible to participate, please call 205-975-8542 or 205-934-2484.

Opportunity to quit smoking cigarettes. Fully remote. If you smoke cigarettes every day, you may be eligible for a research study with the University of Alabama at Birmingham, in conjunctions with MUSC (The Medical University of South Carolina). The research study involves initial online screening, 8 contacts over 6 months and a chance to try varenicline, a prescription smoking cessation medication, or nicotine patches and lozenges. Items are mailed to you if eligible. Compensation is available for those who are eligible and participate. Please follow the link below for more information and to see if you are eligible: https://redcap.musc.edu/surveys/?s=8JWFT9XFY3FYR7Y3

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

We are currently recruiting participants aged 18-30 with normal or corrected to normal vision and participants aged 18-89 with Macular Degeneration/Stargardt's Disease for a clinical research study that aims to understand how individuals learn to use their peripheral vision following the loss of central vision. This study is being conducted in the Civitan International Research Center and involves a total of 27 in-person visits over the course of 1.5 to 3 months. There are 2 MRI visits (1 at the beginning of the study and one at the end), 5 assessment visits (3 baseline assessments and 2 post assessments), and a total of 20 training sessions (in between the baselines and the post assessments). Compensation for full participation in this study is $350.This is a great opportunity for all to gain experience participating in a clinical research study. All participation would not only contribute to advancing our understanding of perceptual learning and how the brain processes vision, but also holds the potential to improve outcomes for those with central vision loss.If you or someone you know may be interested, please consider participating.For more information or to express interest, please email mcmaxwell@uabmc.edu or text or call 205-410-4041, or visit go.uab.edu/brainstudy to sign up!Thank you for your time and consideration!

Participants between the ages of 35 and 65 are needed for this study. The purpose of the study is to fill in what we don’t know about how schizophrenia affects people as they get older. We want to find out what we can do to help older individuals with schizophrenia live better lives. The study includes 4 visits over the course of two weeks. The screening visit will take 2 hours. The first study visit will take 3 hours. The second study visit will take 2 hours. The third study visit will take 9 hours. This study will include: a clinical interview, cognitive batteries, questionnaires and assessments related to your daily and psychiatric functioning, two 90 minute MRI scans of your brain, a fasting blood draw, and a urine drug screen and pregnancy test (for females). Compensation is up to $310. TO SEE IF YOU QUALIFY PLEASE CONTACT (205) 934-8203.

Our study is looking for physically active and inactive postmenopausal women of Black or White race. We are testing the impact of race, exercise habits, and living conditions on heart disease risk in postmenopausal women. Participation only involves two, one-hour long visits to the UAB Center for Exercise Medicine and offers compensation up to $200. If you are interested in participating, please call McKenna Tharpe at (205) 996-3005.

Study Information: Are you 18-60 years of age living with HIV, and want to be a part of a vaccine study? Is your viral load suppressed/undetectable? Are you able to receive a vaccine? Are you generally healthy? Are you willing to temporarily stop taking antiretrovirals? You may qualify for a study looking at testing an experimental HIV vaccine with an experimental adjuvant to see how the immune responses change among participants who do an antiretroviral analytical treatment interruption (ATI) compared to those who do not. Compensation at each study visit will be provided for time and travel. Transportation services are also available upon request. If interested, please email sspaulding@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

If you’ve been feeling stuck and longing for relief, you may be eligible to receive dedicated medical attention, an investigational therapeutic and compensation for your involvement in an innovative research study. We're conducting clinical research in depression to learn how individuals’ brain biology impacts response to treatment, with the goal to help people find relief faster. You do not need to already have a diagnosis to participate. If you’re currently taking medication, you are likely still eligible for our studies and don’t have to stop your existing treatment regimen.For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.

Major Depressive Disorder is a mental health condition characterized by periods of low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. The purpose of this clinical research study is to evaluate the safety and effectiveness of an investigational drug for Major Depressive Disorder, also known as Major Depression. Study participation may include several clinic visits over a period of up to 5 months with an opportunity to conduct some visits either virtually or in-clinic. Qualified participants will receive compensation for their time.For more information about this trial and to see if you qualify, please contact Kristine at kristinepike@uabmc.edu or 205-975-8542.

Are you: A woman who has ever been in jail, prison, or on probation or parole? A woman who has used drugs? Interested in learning about a way to protect yourself against HIV?   You may qualify for a paid research study at the University of Alabama at Birmingham, in partnership with Yale University. Participate in confidential study interviews at our research office. Earn $50 for each interview, up to $225 for participating in the study. Fill out our contact survey at: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_d7sAjr6GDsjiJng?Q_CHL=qr Or you may call 205-934-2851 or email AthenaStudy@uabmc.edu

Researchers from the UAB School of Optometry are currently recruiting those with dry eyes to participate in a research study looking at how a part of your eye's immune system called the complement system is involved in dry eye disease. If eligible, you will be asked to have your eyes evaluated three times, each visit being 3 to 17 days apart. Visit will last between 30 to 90 minutes. You will receive $150 if you are eligible for the study and complete all study procedures. NOW RECRUITING SUBJECTS WITH SJOGREN'S SYNDROME. If you are interested in participating in this research and want to know more about the study, kindly follow this link to fill out our recruitment survey.

University of Alabama at Birmingham is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The research study involves free counseling and treatment provided in a comfortable, supportive setting. The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions. Questionnaires, interviews, and biological measures of smoking will be used to assess the treatment's effects on mood and smoking. Participants will be compensated $50 per session. If you would like to discuss the possibility of volunteering, please call 205-996-1198, or go to www.quitsmokingbaltimore.org for more information about the study and to complete the online study prescreener for the UAB site. Confidentiality will be maintained for all applicants and participants.Volunteers must be 21 years of age or older, and must live within travel distance of the study site in Birmingham.

There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression. To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue. If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you. For more information please contact 205-996-1198 or spremani@uab.edu

Treatment for Urge Urinary Leakage: BEST Study This study will compare the effectiveness of two different treatments for urge urinary incontinence (UUI). One treatment is Botox injections in the bladder, and the other is an oral medication (mirabegron or vibegron).Participants compensated up to $425.For more information about this study, please email or at urogynecology@uabmc.edu or 205-934-5498.

Are you experiencing pain due to endometriosis? Please consider joining a research study looking at a potential new medication to help women experiencing moderate to severe endometriosis-related pain. Study medication provided at no cost. Participants receive compensation for each visit completed. For more information please call 205-934-1322 or email slangan@uabmc.edu.

DAY or NIGHT, when is the best time to take your blood pressure medication?Help us find out by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Healthy participants needed if you are: 18-75 years old No diagnosis of any neurological disorders or psychiatric problems No history of problematic drug/alcohol use in the last 3 months For more information and to determine eligibility, please call the Neuroscience Laboratory of Social Behavior at (205) 934-8203 or email nlsb.uab@gmail.com. **Compensation is provided**