Are you still suffering from Generalized Anxiety Disorder (GAD)? Have you tried prescribed medication but are still experiencing anxiety symptoms? If so, please consider participating in our research study of an investigational drug for GAD. To join this study, potential study participants: must be at least 18 years of age must have taken at least 2 of the following treatments without adequate symptom relief: Paroxetine Venlafaxine XR Duloxetine Escitalopram Buspirone There is no charge for study-related tests or drugs. For more information, please email lalexander@uabmc.edu or call 205-996-5987.

Do you or your child have one of the skin conditions listed below? If so, you may be able to get medical treatment while getting paid to help advance science! Alopecia (hair loss) Atopic Dermatitis (eczema) Psoriasis (scaly red rash) Hidradenitis Suppurativa (boils/abscesses) Vitiligo (depigmented spots) Pyoderma Gangrenosum (nonhealing wound) Lupus Erythematosus (round scaly rash) Benefits of participating in clinical trials: Frequent free dermatology evaluations Cutting edge treatment options Advancement of research Contact us to learn more about our clinical trials! Phone: 205-502-9967 | 205-502-9961Email: dermresearch@uabmc.edu

About the Study The iADAPT study is a 16-week study designed to determine which weight loss program features are most effective in people with a physical disability. Participants will follow one of two diets and may be given additional nutritional or exercise counseling. The study provides weekly coaching, body composition assessment, and lab work to assess diabetes and heart disease risk. Eligibility: Aged 18–75 Overweight/obese BMI Physical disability or mobility impairment Not currently on weight loss medications Reimbursement: Participants will receive up to $150 in compensation for their time. Participants: Come in person to the WHARF on Lakeshore Campus at the beginning and end of the four-month period for testing Receive weekly group coaching on lifestyle changes (via Zoom) May receive additional exercise and diet support as needed Will receive detailed body composition and metabolic assessments Contact Info Omer Faruq Telephone: 205-518-8292 Email: ofaruq@uab.edu

Participate in the PRISM-BP research study at UAB, investigating whether sharing personalized genetic risk scores can help people better control blood pressure. In this study, participants will attend 7 visits over 12 months. The study involves health checks, blood tests, urine samples, activity tracking, and wearing a 24-hour blood pressure monitor. Some participants will also receive their genetic risk score with counseling. Eligible participants must be 18–55 years old, have high blood pressure, and have no history of serious heart or kidney problems. Women cannot be pregnant or breastfeeding. Participants will be compensated up to $360 for completing study visits. Please e-mail Dr. Bal at harshvir6598@uabmc.edu or call us at 205-934-7936 if you are interested.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. In this study, participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Amrita at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-0649 if you are interested.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.

If you are overweight or obese and have Type 2 Diabetes you may qualify for a clinical research study. This clinical trial is studying an investigational medicine. We’re searching for adults aged 18+ years, with a BMI of 27 or greater, and who are keen to take part in clinical research. Qualified participants will receive no-cost study-related exam and investigational drug and may be compensated for time and travel. For more information, contact Tracie Thomas tthoma@uab.edu or 205-996-4015.

Millions of Americans struggle with bipolar depression. If you’ve tried seeking treatment and are still suffering, consider a research study. Local study doctors are studying how your brain's unique biology impacts treatment response in bipolar depression. To participate, you must be 18 years or older, have a diagnosis of bipolar depressive disorder (BPD), be experiencing a current depressive episode, and be taking a current bipolar medication. Contact us about the Alto Study: Candace Green: candacegreen@uabmc.edu or 205-934-2484

The UAB Department of Nutrition Sciences is conducting a nutrition and brain health study looking at whether an acute dose of a ketone supplement can improve cognitive function in individuals 60 and older. You may qualify if you are between the ages of 60-75 years, are healthy or have prediabetes, have NOT been diagnosed with Diabetes, are willing to consume a ketone supplement drink, and are willing to travel to UAB for 2 testing visits that include a PET-fMRI brain scan. Qualified participants will receive PET-fMRI scans upon request and monetary compensation for their time. For more information and to see if you qualify, please call or email sksweatt@uab.edu.

The Alabama Vaccine Research Clinic (AVRC) at UAB is seeking healthy adults ages 18 to 65 to take part in a national HIV prevention study. This Phase 2 clinical trial is testing the safety and potential benefits of three investigational monoclonal antibodies—lab-made proteins that may help the body block HIV. These antibodies are given by IV infusion, not as a shot or vaccine, and participants are never exposed to HIV. Those who qualify will receive two infusions over six months, followed by routine clinic visits for up to one year. Participants will receive compensation for their time and effort. To learn more, call 205-934-7492, email avrc@uabmc.edu.

The UAB Department of Nutrition Sciences, in collaboration with Viking Therapeutics, is conducting a 78 week research study to look into how well VK2735, a GLP-1 and GIP combo investigational once weekly medicine, works at different doses in people with type 2 diabetes and overweight or obesity. Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-2689 or email at alp0029@uab.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. In this study, participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Amrita at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-0649 if you are interested.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.

Do sudden urges to urinate or frequent bathroom trips interrupt your daily routine? You may be eligible to participate in a research study evaluating a new opportunity to explore an innovative digital approach designed to help manage symptoms of overactive bladder (OAB) – all from the comfort of your home. About the Study: Compare two methods: handouts vs. a mobile app to manage bladder health 100% remote participation — no clinic visits required Study coordinators will request a clinic note from a recent doctor’s visit to verify eligibility Who Can Join: Women 22 years of age or older Experiencing frequent urination, sudden urges, or urinary incontinence Must have a working phone number and be able to download and use an app Compensation: You may be eligible to receive compensation for your time and participation. Compensation will be provided via a Visa gift card, mailed to your home. Funds will be added as you complete study milestones. Interested in learning more? https://researchdata.medstar.net/redcap/surveys/?s=MM7WN7EXACX4PNXJ

Learn more about a clinical trial examining a potential new treatment for depression in adult patients. Managing symptoms of depression can feel overwhelming, but you are not alone. If you experience symptoms such as sadness, diminished interest or pleasure in things that you once enjoyed, appetite changes, sleep changes, fatigue, feelings of worthlessness or guilt, or thoughts of suicide or harming yourself, you may qualify for a clinical trial examining a new treatment option for depression. The Vitalize Clinical Study is evaluating a new type of investigational treatment for patients with depression that works differently than traditional antidepressants. The study will include a total of 9 visits with the study doctor, over a period of 14 weeks. If you are qualified to participate, you will receive either the study drug, or placebo, as an oral tablet administered one time per week in the study clinic. As a study participant, you will also receive once-weekly evaluations of your depression and other symptoms, physical examinations and tests of your blood, urine, heart, and brain activity at no cost. This study may be an option for you if you: are a healthy adult aged 18-64 with no other major illnesses have a diagnosis of depression are currently experiencing a major depressive episode that has lasted at least 3 weeks but no longer than 18 months are interested in trying a new treatment option, administered as an oral tablet once per week are interested in receiving thorough evaluations of your depression and health monitoring during your participation in the study are interested in contributing to the growing body of research about depression and new treatment options. For more information on how to qualify for the Vitalize Clinical Study, please email lalexander@uabmc.edu or danagreen@uabmc.edu.

Continuing to experience the effects of depression? You could participate in a research study for adults who have depression. The purpose of the study is to evaluate the safety, efficacy, and maintenance of effect of an investigational medication in people with depression. You may be eligible to participate if you: are 18-74 years of age have been diagnosed with depression have taken antidepressants in the past that did not work well for you are currently taking an antidepressant medication but still have symptoms of depression If you are interested, additional eligibility criteria will be assessed by the study doctor or staff. The study consists of Part 1 and Part 2. In Part 1, you will received the investigational medication or placebo (contains no active medication) for 6 weeks. If you complete Part 1, you will have the option to participate in Part 2. In Part 2, you could receive the investigational medication for up to 16 weeks or more. Qualified patients may receive study-required medical care and investigational study medication at no cost. The study will not pay for other medical care or current medication(s) needed to support your daily health care routine. To learn more about this study, please email lalexander@uabmc.edu or kristinepike@uabmc.edu.

We are currently looking for adults between the ages of 18-60 who are depressed and experienced a happy childhood. Have you been: feeling sad, down, hopeless? experiencing increased/decreased appetite? having difficulty concentrating? feeling weary of life? If so, you may be eligible for our Non-treatment study. Participants will be compensated for participating. If you are interested or have any questions, please visit https://tinyurl.com/UABpsychiatricresearch or call (205) 975-2484.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. In this study, participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Are you at least 18 years old and have been previously diagnosed with Attention-Deficit/Hyperactivity Disorder (ADHD) and would like or are in need of a comprehensive psychological evaluation? If so, you may be eligible to participate in a research study where you will receive a free comprehensive psychological evaluation involving a diagnostic interview, cognitive testing such as achievement and intelligence testing, and a personality assessment. Participation involves approximately 7 to 8 hours of a full psychological evaluation to assess you for ADHD and other potential mental health concerns. The assessment may occur over either one or multiple days, depending on your preference. In exchange for participation, all participants will receive a full comprehensive psychological report detailing the findings of your evaluation. This report will be a standard medical report that can be utilized to seek mental health treatment, academic or work accommodations, or meet other needs. If you are interested in participating, please visit the following survey link: https://uab.co1.qualtrics.com/jfe/form/SV_72jKfhVIiFdZKyW If you have any questions, please reach out to either Drew Whittington at whitdrew@uab.edu or Dr. Nicholas Borgogna at borgogna@uab.edu.