We are unlocking new gateways to treating depression and we are looking for volunteers to participate in a clinical trial. Who's eligible for the study?If you have been diagnosed with depression.If you are between the ages of 18-64If you are currently experiencing a major depressive episode that has lasted at least 3 weeks but not longer than 18 months.If you are otherwise healthy and have not been diagnosed with other medically important conditions or psychiatric conditions such as bipolar disorder (BP), antisocial personality disorder (ASPD), obsessive compulsive disorder (OCD), borderline personality disorder (BPD) or attention-deficit/hyperactivity disorder (ADHD) or major diseases, have not had electroconvulsive therapy (ECT), vagus nerve stimulation (VNS), deep brain stimulation or repetitive transcranial magnetic stimulation (TMS) within 5 years or have failed to respond to ECT at any time, This STUDY Might Be For You!For more information, contact Dana Green at danagreen@uabmc.edu or 205-975-6426.

You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at (205)934-0534 or email us at nauticalstudy@uabmc.edu.

Participate in the PRECISION-BP research study investigating the best time to take blood pressure medication, morning or evening. This study participants will receive blood pressure medications for 28 days. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.

Are you between the ages of 18-60? The UAB Office of Psychiatric Research is actively recruiting participants for our studies and wants to connect with you on our research! Whether you are needing someone to talk to, or even have no history of mental health conditions and are just wanting to further knowledge within the medical and mental health field, we would love to get you involved!Our studies can be broken down into two different categories:1) TREATMENT STUDIES – Our Treatment Studies are designed to evaluate the effectiveness of new antidepressants on individuals living with Major Depressive Disorder or Treatment-Resistant Depression.2) NON-TREATMENT STUDIES – Our Non-Treatment Studies do NOT involve testing a new medication or intervention. Instead, these studies focus on understanding behaviors and experiences of mental health conditions via interviews, tests, or surveys.COMPENSATION IS PROVIDED!For more information, please reach out to the UAB Office of Psychiatric Research at (205) 934-2484 or go to: https://tinyurl.com/UABpsychiatricresearch and our team will be in contact with you shortly!

Interested in being part of vision rehabilitation research for healthy older adults aged 50-59 to lay the foundation of using a new device? Here is an overview of what our study will involve! The purpose of this study? Calculate baseline data for Bioness Integrated Therapy System (BITS) and identify its clinical implications in treating visual impairments. Compare the baseline data of Bioness Integrated Therapy System (BITS) to Dynavision for visual scanning. Who are we looking for? Healthy adults aged 50-59 without physical, visual, or cognitive impairment and with no history of seizures or balance problems. Adults who are able to walk without assistive devices and are English speakers. What would you have to do in 60 minutes? Fill out a short survey for demographic data. Quick functional screening of upper extremities. Perform four tests on BITS. Perform four tests on Dynavision. Participants will receive a $25 gift card. To participate in the study, please fill out this short survey:https://uab.co1.qualtrics.com/jfe/form/SV_exEYGMKXxc230p0 For more information, please contact us at almulhim@uab.edu

We are looking for volunteers to participate in a clinical study to advance lupus treatment.If you are interested in seeing if you may qualify for an ongoing clinical study, please contact Christina Ndolo at cmndolo@uabmc.edu.

Our study is looking for physically active and inactive postmenopausal women of Black or White race. We are testing the impact of race, exercise habits, and living conditions on heart disease risk in postmenopausal women. Participation only involves two, one-hour long visits to the UAB Center for Exercise Medicine and offers compensation up to $200. If you are interested in participating, please call McKenna Tharpe at (205) 996-3005.

Study Information: Are you 18-60 years of age living with HIV, and want to be a part of a vaccine study? Is your viral load suppressed/undetectable? Are you able to receive a vaccine? Are you generally healthy? Are you willing to temporarily stop taking antiretrovirals? You may qualify for a study looking at testing an experimental HIV vaccine with an experimental adjuvant to see how the immune responses change among participants who do an antiretroviral analytical treatment interruption (ATI) compared to those who do not. Compensation at each study visit will be provided for time and travel. Transportation services are also available upon request. If interested, please email sspaulding@uabmc.edu.

You may be eligible to participate in a research study: If you are a healthy female, between age of 18-50, still having a regular menstrual cycle & you are NOT on hormonal birth control (birth control pills or shots (i.e. Depo shot) or IUD, like Mirena). And, if you are willing to undergo an endometrial biopsy procedure and blood draw. Participants will be compensated a total of $200. Only requires 2 visits.For information, call us at 205-934-5498 or email: urogynecology@uabmc.edu

Are you: A woman who has ever been in jail, prison, or on probation or parole? A woman who has used drugs? Interested in learning about a way to protect yourself against HIV?   You may qualify for a paid research study at the University of Alabama at Birmingham, in partnership with Yale University. Participate in confidential study interviews at our research office. Earn $50 for each interview, up to $225 for participating in the study. Fill out our contact survey at: https://yalesurvey.ca1.qualtrics.com/jfe/form/SV_d7sAjr6GDsjiJng?Q_CHL=qr Or you may call 205-934-2851 or email AthenaStudy@uabmc.edu

Researchers from the UAB School of Optometry are currently recruiting those with dry eyes to participate in a research study looking at how a part of your eye's immune system called the complement system is involved in dry eye disease. If eligible, you will be asked to have your eyes evaluated three times, each visit being 3 to 17 days apart. Visit will last between 30 to 90 minutes. You will receive $150 if you are eligible for the study and complete all study procedures. NOW RECRUITING SUBJECTS WITH SJOGREN'S SYNDROME. If you are interested in participating in this research and want to know more about the study, kindly follow this link to fill out our recruitment survey.

University of Alabama at Birmingham is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The research study involves free counseling and treatment provided in a comfortable, supportive setting. The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions. Questionnaires, interviews, and biological measures of smoking will be used to assess the treatment's effects on mood and smoking. Participants will be compensated $50 per session. If you would like to discuss the possibility of volunteering, please call 205-996-1198, or go to www.quitsmokingbaltimore.org for more information about the study and to complete the online study prescreener for the UAB site. Confidentiality will be maintained for all applicants and participants.Volunteers must be 21 years of age or older, and must live within travel distance of the study site in Birmingham.

There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression. To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue. If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you. For more information please contact 205-996-1198 or spremani@uab.edu

Treatment for Urge Urinary Leakage: BEST Study This study will compare the effectiveness of two different treatments for urge urinary incontinence (UUI). One treatment is Botox injections in the bladder, and the other is an oral medication (mirabegron or vibegron).Participants compensated up to $425.For more information about this study, please email or at urogynecology@uabmc.edu or 205-934-5498.

Are you experiencing pain due to endometriosis? Please consider joining a research study looking at a potential new medication to help women experiencing moderate to severe endometriosis-related pain. Study medication provided at no cost. Participants receive compensation for each visit completed. For more information please call 205-934-1322 or email slangan@uabmc.edu.

UAB is looking for participants for a study investigating the effects of a new study medication on symptoms of fibromyalgia. We are looking for women aged 25-65 who are diagnosed with fibromyalgia OR are experiencing chronic widespread bodily pain. Participants will come to UAB for 7 study visits over a 3-month period. Participants will be compensated for completing all study visits. Please call 205-996-1198 if interested.

If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.

UAB researchers are looking for adults (ages 25-65) who are suffering from demoralization - feelings of hopelessness or meaninglessness - to participate in a research study evaluating a novel medication.To see if you qualify call 205-379-7527.

Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.