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Faculty and trainees in the division of Anatomic Pathology published the following articles March-May, 2020:

Dr. Sameer Al Diffalha
Dr. Upender Manne

Agarwal S, Behring M, Kim HG, Bajpai P, Chakravarthi BVSK, Gupta N, Elkholy
A, Al Diffalha S, Varambally S, Manne U. Targeting P4HA1 with a Small Molecule
Inhibitor in a Colorectal Cancer PDX Model.
Transl Oncol. 2020 Mar
18;13(4):100754. doi: 10.1016/j.tranon.2020.100754. Epub ahead of print. PMID:
32199274; PMCID: PMC7082635.

Dr. Sameer Al Diffalha

Agarwal S, Chakravarthi BVSK, Behring M, Kim HG, Chandrashekar DS, Gupta N,
Bajpai P, Elkholy A, Balasubramanya SAH, Hardy C, Diffalha SA, Varambally S,
Manne U. PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor
Growth and the Metastasis of Colorectal Cancer. Cancers (Basel)
. 2020 Mar
25;12(4):E772. doi: 10.3390/cancers12040772. PMID: 32218208.

Dr. David Crowe

Mariappan N, Husain M, Zafar I, Singh V, Smithson KG, Crowe DR, Pittet JF,
Ahmad S, Ahmad A. Extracellular nucleic acid scavenging rescues rats from sulfur
mustard analog-induced lung injury and mortality
. Arch Toxicol. 2020 Mar 10.
doi: 10.1007/s00204-020-02699-1. Epub ahead of print. PMID: 32157350.

Dr. Deepti Dhall

Wong M, Barrows B, Gangi A, Kim S, Mertens RB, Dhall D. Low-Grade Appendiceal
Mucinous Neoplasms: A Single Institution Experience of 64 Cases With Clinical
Follow-up and Correlation With the Current (Eighth Edition) AJCC Staging
. Int J
Surg Pathol. 2020 May;28(3):252-258. doi: 10.1177/1066896919883679. Epub 2019
Oct 24. PMID: 31645160.

Dr. Virginia Duncan

Duncan VE, Chisholm KM, Pacheco MC. Effects of Tumor Necrosis Factor Alpha
Inhibitors on Lymph Node and Ileocecal Mucosa-Associated Lymphoid Tissue
Architecture in Patients With Inflammatory Bowel Disease.
Pediatr Dev Pathol.
2020 Mar-Apr;23(2):115-120. doi: 10.1177/1093526619866371. Epub 2019 Jul 30.
PMID: 31362580.

Dr. Eldin-Isam Eltoum

Rodriguez Pena MDC, Springer SU, Taheri D, Li L, Tregnago AC, Eich ML, Eltoum
IA, VandenBussche CJ, Papadopoulos N, Kinzler KW, Vogelstein B, Netto GJ.
Performance of novel non-invasive urine assay UroSEEK in cohorts of equivocal
urine cytology
. Virchows Arch. 2020 Mar;476(3):423-429. doi:
10.1007/s00428-019-02654-1. Epub 2019 Sep 3. PMID: 31482302.

Dr. Eldin-Isam Eltoum

Castle PE, Burk RD, Massad LS, Eltoum IE, Hall CB, Hessol NA, Anastos K, Xie
X, Minkoff H, Xue X, D'Souza G, Flowers L, Colie C, Rahangdale L, Fischl MA,
Palefsky JM, Strickler HD. Epidemiological evidence that common HPV types may be
common because of their ability to evade immune surveillance: Results from the
Women's Interagency HIV study
. Int J Cancer. 2020 Jun 15;146(12):3320-3328. doi:
10.1002/ijc.32693. Epub 2019 Oct 18. PMID: 31577842.

Dr. Huma Fatima
Dr. Frida Rosenblum

Royal V, Leung N, Troyanov S, Nasr S, Écotière L, LeBlanc R, Adam BA, Angioi
A, Alexander M, Asunis AM, Barreca A, Bianco P, Cohen C, Drosou ME, Fatima H,
Fenoglio R, Gougeon F, Goujon JM, Herrera GA, Knebelmann B, Lepori N, Maletta F,
Manso R, Motwani SS, Pani A, Rabant M, Rennke HG, Roccatello D, Rosenblum F,
Sanders P, Santos A, Soto K, Sis B, Touchard G, Venner CP, Bridoux F.
Clinicopathologic predictors of renal outcomes in light chain cast nephropathy:
A multicenter retrospective study.
Blood. 2020 Mar 11:blood.2019003807. doi:
10.1182/blood.2019003807. Epub ahead of print. PMID: 32160635.


Dr. Shuko Harada
Dr. William Grizzle

Demark-Wahnefried W, Rogers LQ, Gibson JT, Harada S, Frugé AD, Oster RA,
Grizzle WE, Norian LA, Yang ES, Della Manna D, Jones LW, Azrad M, Krontiras H.
Randomized trial of weight loss in primary breast cancer: Impact on body
composition, circulating biomarkers and tumor characteristics
. Int J Cancer.
2020 May 15;146(10):2784-2796. doi: 10.1002/ijc.32637. Epub 2019 Sep 5. PMID:
31442303; PMCID: PMC7155016.

Dr. Shuko Harada

Yamashita D, Minata M, Ibrahim AN, Yamaguchi S, Coviello V, Bernstock JD,
Harada S, Cerione RA, Tannous BA, La Motta C, Nakano I. Identification of
ALDH1A3 as a Viable Therapeutic Target in Breast Cancer Metastasis-Initiating
. Mol Cancer Ther. 2020 May;19(5):1134-1147. doi:
10.1158/1535-7163.MCT-19-0461. Epub 2020 Mar 3. PMID: 32127468.

Dr. Shuko Harada

Goswami RS, Harada S. An Overview of Molecular Genetic Diagnosis Techniques.
Curr Protoc Hum Genet.
2020 Mar;105(1):e97. doi: 10.1002/cphg.97. PMID:

Dr. Shuko Harada

Davis BH, DeFrank G, Limdi NA, Harada S. Validation of the Spartan RXCYP2C19
Genotyping Assay Utilizing Blood Samples
. Clin Transl Sci. 2020
Mar;13(2):260-264. doi: 10.1111/cts.12714. Epub 2019 Nov 29. PMID: 31664775;
PMCID: PMC7070822.

Dr. Robin Hatton
Dr. Casey Weaver

DiToro D, Harbour SN, Bando JK, Benavides G, Witte S, Laufer VA, Moseley C,
Singer JR, Frey B, Turner H, Bruning J, Darley-Usmar V, Gao M, Conover C, Hatton
, Frank S, Colonna M, Weaver CT. Insulin-Like Growth Factors Are Key
Regulators of T Helper 17 Regulatory T Cell Balance in Autoimmunity
. Immunity.
2020 Apr 14;52(4):650-667.e10. doi: 10.1016/j.immuni.2020.03.013. PMID:


Dr Silvio Litovsky

Regal-McDonald K, Somarathna M, Lee T, Litovsky SH, Barnes J, Peretik JM,
Traylor JG Jr, Orr AW, Patel RP. Assessment of ICAM-1 N-glycoforms in mouse and
human models of endothelial dysfunction
. PLoS One. 2020 Mar 24;15(3):e0230358.
doi: 10.1371/journal.pone.0230358. PMID: 32208424; PMCID: PMC7092995.

Dr. Cristina Magi-Galluzzi

Gandhi JS, Smith SC, Paner GP, McKenney JK, Sekhri R, Osunkoya AO, Baras AS,
DeMarzo AM, Cheville JC, Jimenez RE, Trpkov K, Colecchia M, Ro JY, Montironi R,
Menon S, Hes O, Williamson SR, Hirsch MS, Netto GJ, Fine SW, Sirohi D, Kaushal
S, Sangoi A, Robinson BD, Kweldam CF, Humphrey PA, Hansel DE, Schultz L, Magi-
Galluzzi C, Przybycin CG, Shah RB, Mehra R, Kunju LP, Aron M, Kryvenko ON, Kench
JG, Kuroda N, Tavora F, van der Kwast T, Grignon DJ, Epstein JI, Reuter VE, Amin
MB. Reporting Practices and Resource Utilization in the Era of Intraductal
Carcinoma of the Prostate: A Survey of Genitourinary Subspecialists
. Am J Surg
Pathol. 2020 May;44(5):673-680. doi: 10.1097/PAS.0000000000001417. PMID:

Dr. Cristina Magi-Galluzzi

Nguyen JK, Przybycin CG, McKenney JK, Magi-Galluzzi C. Immunohistochemical
staining patterns of Ki-67 and p53 in florid reactive urothelial atypia and
urothelial carcinoma in situ demonstrate significant overlap.
Hum Pathol. 2020
Mar 3;98:81-88. doi: 10.1016/j.humpath.2020.02.008. Epub ahead of print. PMID:

Dr. Upender Manne
Dr. William Grizzle

Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S,
Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G,
Della Manna DL, Acharya KK, Carskadon S, Manne U, Crossman DK, Ferguson JE,
Grizzle WE, Palanisamy N, Willey CD, Crowley MR, Netto GJ, Yang ES, Varambally
S, Sonpavde G. Therapeutically actionable PAK4 is amplified, overexpressed, and
involved in bladder cancer progression.
Oncogene. 2020 Mar 30. doi:
10.1038/s41388-020-1275-7. Epub ahead of print. PMID: 32231273.

Dr. Upender Manne
Dr. Sameer Al Diffalha

Agarwal S, Chakravarthi BVSK, Behring M, Kim HG, Chandrashekar DS, Gupta N,
Bajpai P, Elkholy A, Balasubramanya SAH, Hardy C, Diffalha SA, Varambally S,
Manne U. PAICS, a Purine Nucleotide Metabolic Enzyme, is Involved in Tumor
Growth and the Metastasis of Colorectal Cancer.
Cancers (Basel). 2020 Mar
25;12(4):E772. doi: 10.3390/cancers12040772. PMID: 32218208.

Dr. Gene Siegal

Sobel ME, Dreyfus JC, Dillehay McKillip K, Kolarcik C, Muller WA, Scott MJ,
Siegal GP, Wadosky K, O'Leary TJ. Return of Individual Research Results: A Guide
for Biomedical Researchers Utilizing Human Biospecimens
. Am J Pathol. 2020
May;190(5):918-933. doi: 10.1016/j.ajpath.2020.01.014. Epub 2020 Mar 19. PMID:

Dr. Shi Wei
Dr. Gene Siegal
Dr. James Hackney

Wang K, Hackney JR, Siegal GP, Wei S. RANKLed by the Complexity of Signaling
in Breast Cancer Metastasis to the Brain
. Clin Breast Cancer. 2020 Apr
11:S1526-8209(20)30071-9. doi: 10.1016/j.clbc.2020.04.001. Epub ahead of print.
PMID: 32381383.

Dr. Shi Wei

Zheng L, Abdelgawwad MS, Zhang D, Xu L, Wei S, Cao W, Zheng XL. Histone-
induced thrombotic thrombocytopenic purpura in <i>adamts13</i><sup>-/-</sup>
zebrafish depends on von Willebrand factor.
Haematologica. 2020
Apr;105(4):1107-1119. doi: 10.3324/haematol.2019.237396. Epub 2019 Nov 21. PMID:
31753928; PMCID: PMC7109750.

Dr. Shi Wei

Wei S, Ching YC, Chuah CH. Synthesis of chitosan aerogels as promising
carriers for drug delivery: A review.
Carbohydr Polym. 2020 Mar 1;231:115744.
doi: 10.1016/j.carbpol.2019.115744. Epub 2019 Dec 16. PMID: 31888854.

Dr. Shi Wei

Wei S, Yu-Han Z, Wei-Wei J, Hai Y. The effects of intravenous lidocaine on
wound pain and gastrointestinal function recovery after laparoscopic colorectal
. Int Wound J. 2020 Apr;17(2):351-362. doi: 10.1111/iwj.13279. Epub 2019
Dec 13. PMID: 31837112.

Dr. Shi Wei

Reisenbichler ES, Han G, Bellizzi A, Bossuyt V, Brock J, Cole K, Fadare O,
Hameed O, Hanley K, Harrison BT, Kuba MG, Ly A, Miller D, Podoll M, Roden AC,
Singh K, Sanders MA, Wei S, Wen H, Pelekanou V, Yaghoobi V, Ahmed F, Pusztai L,
Rimm DL. Prospective multi-institutional evaluation of pathologist assessment of
PD-L1 assays for patient selection in triple negative breast cancer.
Mod Pathol.
2020 Apr 16. doi: 10.1038/s41379-020-0544-x. Epub ahead of print. PMID:

Dr. Shi Wei

Kundu A, Nam H, Shelar S, Chandrashekar DS, Brinkley G, Karki S, Mitchell T,
Livi CB, Buckhaults P, Kirkman R, Tang Y, Rowe GC, Wei S, Varambally S,
Sudarshan S. PRDM16 suppresses HIF-targeted gene expression in kidney cancer. J
Exp Med. 2020 Jun 1;217(6):e20191005. doi: 10.1084/jem.20191005. PMID: 32251515.

Dr. Shi Wei

Liu W, Zhang Y, Wei S, Bae S, Yang WH, Smith GJ, Mohler JL, Fontham ETH,
Bensen JT, Sonpavde GP, Chen GY, Liu R, Wang L. A CD24-p53 axis contributes to
African American prostate cancer disparities
. Prostate. 2020 May;80(8):609-618.
doi: 10.1002/pros.23973. Epub 2020 Mar 13. PMID: 32168400; PMCID: PMC7176538.