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September 2023 Newsletter

September 2023 Newsletter

UAB-UCSD O’Brien Center for Acute Kidney Injury Research became a member of the O’Brien Kidney Consortium as one of seven U54 National Resource Centers (U54 DK137307). As we make this transition, we reflect on the past 15 years as an O’Brien P30 (P30 DK079337) and want to highlight some of our accomplishments and activities.

 

March 2023 Newsletter

March 2023 Newsletter

The Education and Enrichment Programs of the O’Brien Center include symposia, seminar series, workshops, sabbaticals, and the Medical Student Summer Research Program (MSSRP). Through these efforts, individuals across the pipeline are encouraged to learn more about acute kidney injury research. This program leverages offerings of other training programs at UAB and UCSD to provide a continued pipeline approach to enhancing research on AKI.

 

October 2022 Newsletter

October 2022 Newsletter

The UAB-UCSD O’Brien Center’s Educational and Enrichment Programs are intended to catalyze collaborative interactions among Center members, enhance the expertise of investigators, foster the development of renal projects and research, and train the next generation of investigators. Through symposia, seminar series, workshops, and sabbaticals, individuals are granted access to innovative acute kidney injury research and education.

 

June 2022 Newsletter

June 2022 Newsletter

The Biostatistical Resource provides statistical support to the research projects, pilot projects, and the other cores in the UAB-UCSD O'Brien Center. This program offers planning advice to investigators looking to create a project proposal. Experts generally begin to work with pilot grantees once their letter of interest is submitted.

 

January 2022 Newsletter

January 2022 Newsletter

Core C of the O’Brien Center offers support to acute kidney injury investigators in small molecule, biomarker, and mitochondrial function analysis.

Isotope dilution analysis of creatinine has passed the 60,000 assays point. Metabolomics, a comprehensive assay of all small molecules (cell metabolites, food-derived compounds, bacterial metabolites, drugs and personal products) in biofluids and tissues has been applied to a study of COVID-19 patients with and without AKI...

 

September 2021 Newsletter

September 2021 Newsletter

Core B, the resource for pre-clinical studies of AKI, has two new methodologies developed by its Renal Physiology Sub-Core:

A mouse model that converts the C57BL/6 mouse strain from being CKD resistant in response to subtotal nephrectomy (STN) to “CKD susceptible.”

 

May 2021 Newsletter

May 2021 Newsletter

The Clinical Studies in AKI Core offers access to comprehensive datasets of patients who’ve been diagnosed with AKI as well as control (non-AKI populations). They also offer a biological sample repository with access to tissues, blood and urine samples. This core can facilitate your planning and design process of clinical research studies from collection to analysis.