O'Brien Newsletter - School of Medicine - O'Brien Center

January 2022 Newsletter

Core C of the O’Brien Center offers support to acute kidney injury investigators in small molecule, biomarker, and mitochondrial function analysis.

Isotope dilution analysis of creatinine has passed the 60,000 assays point. Metabolomics, a comprehensive assay of all small molecules (cell metabolites, food-derived compounds, bacterial metabolites, drugs and personal products) in biofluids and tissues has been applied to a study of COVID-19 patients with and without AKI...

September 2021 Newsletter

Core B, the resource for pre-clinical studies of AKI, has two new methodologies developed by its Renal Physiology Sub-Core:

A mouse model that converts the C57BL/6 mouse strain from being CKD resistant in response to subtotal nephrectomy (STN) to “CKD susceptible.”

May 2021 Newsletter

The Clinical Studies in AKI Core offers access to comprehensive datasets of patients who’ve been diagnosed with AKI as well as control (non-AKI populations). They also offer a biological sample repository with access to tissues, blood and urine samples. This core can facilitate your planning and design process of clinical research studies from collection to analysis.

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