Recent Publications


Awidishu L, Joy MS. (2016) Role of Pharmacogenomics in Kidney Disease and Injury. Adv Chronic Kidney Dis. 23(2):106-119. Review.

Barnes S, Benton HP, Casazza K, Cooper SJ, Cui X, Du X, Engler J, Kabarowski JH, Li S, Pathmasiri W, Prasain JK, Renfrow MB, Tiwari HK. (2016) Training in metabolomics research. I. Designing the experiment, collecting and extracting samples and generating metabolomics data. J Mass Spectrom. 51(7):461-475. PMCID: PMC4964969.

Bolisetty S, Traylor A, Joseph R, Zarjou A, Agarwal A. (2016) Proximal tubule-targeted heme oxygenase-1 in cisplatin-induced acute kidney injury. Am J Physiol Renal Physiol. 310(5):F385-F394. PMCID: PMC4868370.

Chacko BK, Zhi D, Darley-Usmar VM, Mitchell T. (2016) The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes. Redox Biol. 8:43-50. PMCID: PMC4712317.

Hull TD, Boddu R, Guo L, Tisher CC, Traylor AM, Patel B, Joseph R, Prabhu SD, Suliman HB, Piantadosi CA, Agarwal A, George JF. (2016) Heme osygenase-1 regulates mitochondrial quality control in the heart. JCI Insight. 1(2):e85817. PMCID: PMC4838906.

Larson-Casey JL, Deshane JS, Ryan AJ, Thannickal VJ, Carter AB. (2016) Macrophage Akt1 Kinase-Mediated Mitophagy Modulates Apoptosis Resistance and Pulmonary Fibrosis. Immunity. 44(3):582-596. PMCID: PMC4794358.

Lebensburger JD, Palabindela P, Howard TH, Feig DI, Aban I, Askenazi DJ. (2016) Prevelance of acute kidney injury during pediatric admissions for acute chest syndrome. Pediatr Nephrol. 31(8):1363-1368. PMCID: PMC4920695.

Maarouf OH, Aravamudhan A, Rangarajan D, Kusaba T, Zhang V, Welborn J, Gaubin D, Hou X, Kramann R, Humphreys BD. (2016) Paracrine Wnt1 Drives Interstitial Fibrosis without Inflammation by Tubulointerstitial Cross-Talk. J Am Soc Nephrol. 27(3):781-790. PMCID: PMC4769196.

Macedo E, Mehta RL. (2016) Renal Recovery after Acute Kidney Injury. Contrib Nephrol. 187:24-35. Review.

Mehta RL. (2016) Renal-Replacement Therapy in the Critically Ill—Does Timing Matter? N Engl J Med. 375(2):175-176. Commentary.

Mehta RL, Burdmann EA, Cerda J, Feehally J, Finkelstein F, Garcia-Garcia G, Godin M, Jha V, Lameire NH, Levin NW, Lewington A, Lombardi R, Macedo E, Rocco M, Aronoff-Spencer E, Tonelli M, Zhang J, Remuzzi G. (2016) Recognition and management of acute kidney injury in the International Society of Nephrology 0by25 Global Snapshot: a multinational cross-sectional study. Lancet. 387(10032):2017-2025.

Novikov A, Vallon V. (2016) Sodium glucose contransporter 2 inhibition in the diabetic kidney: an update. Curr Opin Nephrol Hypertens. 25(1):50-58. Review.

Panwar B, Judd SE, Warnock DG, McClellan WM, Booth JN 3rd, Muntner P, Gutierrez OM. (2016) Hemoglobin Concentration and Risk of Incident Stroke in Community-Living Adults. Stroke. 47(8):2017-2024. PMCID: PMC4961542.

Peagues MA, McWilliams IL, Szalai AJ. (2016) C-reactive protein exacerbates renal ischemia-reperfusion injury: are myeloid-derived suppressor cells to blame? Am J Physiol Renal Physiol. 311(1):F176-F181. PMCID Journal – In Process.

Rao S, Walters KB, Wilson L, Chen B, Bolisetty S, Graves D. Barnes S, Agarwal A, Kabarowski JH. (2016) Early lipid changes in acute kidney injury using SWATH lipidomics couples with MALDI tissue imaging. Am J Physiol Renal Physiol. 310(10):F1136-F1147. PMCID: PMC4889318.

Ravi S, Johnson MS, Chacko BK, Kramer PA, Sawada H, Locy ML, Wilson LS, Barnes S, Marques MB, Darley-Usmar VM. (2016) Modification of platelet proteins by 4-hydroxynonenal: Potential Mechanisms for inhibition of aggregation and metabolism. Free Radic Biol Med.91:143-153. PMCID: PMC4761519.

Smith MR, Vayalil PK, Zhou F, Benavides GA, Beggs RR, Golzarian H, Nijampatnam B, Oliver PG, Smith RA, Murphy MP, Velu SE, Landar A. (2016) Mitochondrial thiol modification by targeted electrophile inhibits metabolism in breast adenocarcinoma cells by inhibiting enzyme activity and protein levels. Redox Biol. 8:136-148. PMCID: PMC4732023.

Tran MT, Zsengeller ZK, Berg AH, Khankin EV, Bhasin MK, Kim W, Clish CB, Stillman IE, Karumanchi SA, Rhee EP, Parikh SM. (2016) PGC1α drives NAD biosynthesis linking oxidative metabolism to renal protection. Nature. 531(7595):528-532. PMCID: PMC4909121.

Vallon V. (2016) Tubular Transport in Acute Kidney Injury: Relevance for Diagnosis, Prognosis and Intervention. Nephron. [Epub ahead of print]

Weir MR, Blantz RC. (2016) Noteworthy observation in hypertension from 2015. Curr Opin Nephrol Hypertens. 25(1):1-2. Review.

Williams J, Homes RP, Assimos DG, Mitchell T. (2016) Monocyte Mitochondrial Function in Calcium Oxalate Stone Formers. Urology 93:224.e1-224.e6. PMCID: PMC4914421.


Archived Publications


Askenazi DJ, Halloran B, Patil N, Keeling S, Saeidi B, Koralkar R, Ambalavanan N. (2015) Genetic polymorphisms of heme-oxygenase 1 (HO-1) may impact on acute kidney injury, bronchopulmonary dysplasia, and mortality in premature infants. Pediatr Res. 77(6):793-798. PMCID: PMC4439308.

Bajwa A, Rosin DK, Chroscicki P, Lee S, Dondeti K, Ye H, Kinsey GR, Stevens BK, Jobin K, Kenwood BM, Hoehn KL, Lynch KR, Okusa MD. (2015) Sphingosine 1-phosphate receptor-1 enhances mitochondrial function and reduces cisplatin-induced tubule injury. J Am Soc Nephrol. 26(4):908-925. PMCID: PMC4378101.

Black LL, Srivastava R, Schoeb TR, Moore RD, Barnes S, Kabarowski JH. (2015) Cholesterol-Independent Supression of Lymphocyte Activation, Autoimmunity, and Glomerulonephritis by Apolipoprotein A-I in Normocholesterolemic Lupus-Prone Mice. J Immunol. 195(10):4685-4698. PMCID: PMC4637240.

Blantz RC, Steiner RW. (2015) Benign hyperfiltration after living kidney donation. J Clin Invest. 125(3):972-974. PMCID PMC4362244.

Boddu R, Hull TD, Bolisetty S, Hu X, Moehle MS, Daher JP, Kamal AI, Joseph R, George JF, Agarwal A, Curtis LM, West AB. (2015) Leucine-rich repeat kinase 2 deficiency is protective in rhabdomolysis-induced kidney injury. Hum Mol Genet. 24(14):4078-4093. PMCID: PMC4476452.

Bolisetty S, Zarjou A, Hull TD, Traylor AM, Perianayagam A, Joseph R, Kamal AI, Arosio P, Soares MP, Jeney V, Balla J, George JF, Agarwal A. (2015) Macrophage and epithelial cell H-ferritin expression regulates renal inflammation. Kidney Int. 88(1):95-108. PMCID: PMC4490000.

Bouchard J, Acharya A, Cerda J, Maccariello ER, Madarasu RC, Tolwani AJ, Liang X, Fu P, Liu ZH, Mehta RL. (2015) A Prospective International Multicenter Study of AKI in the Intensive Care Unit. Clin J Am Soc Nephrol. 10(8):1324-1331. PMCID: PMC4527019.

Conway KS, Forbang N, Beben T, Criqui MH, Ix JH, Rifkin DE. (2015) Relationship Between 24-Hour Ambulatory Blood Pressure and Cognitive Function in Community-Living Older Adults: The UCSD Ambulatory Blood Pressure Study. Am J Hypertens. 28(12):1444-1452. PMCID: PMC4654763.

Dominguez Rieg JA, Burt JM, Ruth P, Rieg T. (2015) P2Y2 receptor activation decreases blood pressure via intermediate conductance potassium channels and connexin 37. Acta Physio (Oxf) 213(3):628-641. PMCID PMC4442688.

Feng W, Chumley P, Prieto MC, Miyada K, Seth DM, Fatima H, Hua P, Rezonzew G, Sanders PW, Jaimes EA. (2015) Transcription factor avian erythroblastosis virus E26 oncogen homolog-1 is a novel mediator of renal injury in salt-sensitive hypertension. Hypertension. 65(4):813-820. PMCID: PMC4897962.

Feng W, Ying WZ, Aaron KJ, Sanders PW. (2015) Transforming growth factor-β mediates endothelial dysfunction in rats during high salt intake. Am J Physiol Renal Physiol. 309(12):F1018-F1025. PMCID: PMC4683308.

Fenton RA, Poulsen SB, de la Mora Chavez S, Soleimani M, Busslinger M, Dominguez Rieg JA, Rieg T. (2015) Caffeine-induced diuresis and natriuresis is independent of rental tubular NHE3. Am J Physiol Renal Physiol. 308(12):F1409-F1420. PMCID: PMC4587593.

Fu Y, Gerasimova M, Batz F, Kuczkowski A, Alam Y, Sander PW, Ronzaud C, Hummler E, Vallon V. (2015) PPARγ agonist-induced fluid retention depends on αENaC expression in connecting tubules. Nephron. 129(1):68-74. PMCID: PMC4323851.

Gallo LA, Wright EM, Vallon V. (2015) Probing SGLT2 as a therapeutic target for diabetes: basic physiology and consequences. Diab Vasc Dis Res. 12(2):78-89. Review.

Girkin CA, Nievergelt CM, Kuo JZ, Maihofer AX, Huisingh C, Liebmann JM, Ayyagari R, Weinreb RN, Ritch R, Zangwill LM, ADAGES Study Group. (2015) Biogeographic Ancestry in the African Descent and Glaucoma Evaluation Study (ADAGES): Association With Corneal and Optic Nerve Structure. Invest Ophthalmol Vis Sci. 56(3):2043-2049. PMCID: PMC4373542.

Godin M, Murray P, Mehta RL. (2015) Clinical approach to the patient with AKI and sepsis. Semin Nephrol. 35(1):12-22. Review.

Hanks LJ, Casazza K, Ashraf AP, Wallace S, Gutierrez OM. (2015) Fibroblast growth factor-21 body composition, and insulin resistance in pre-pubertal and early pubertal males and females. Clin Endocrinol (Oxf). 82(4):550-556. PMCID: PMC4289452.

Hanks LJ, Gutierrez OM, Ashraf AP, Casazza K. (2015) Bone Mineral Content as a Driver of Energy Expenditure in Prepubertal and Early Pubertal Boys. J Pediatr. 166(6):1397-1403. PMCID: PMC4446221.

Hanks LJ, Gutierrez OM, Bamman MM, Ashraf A, McCormick KL, Casazza K. (2015) Circulating levels of fibroblast growth factor-21 increase with age independently of body composition indices among healthy individuals. J Clin Transl Endocrinol. 2(2):77-82. PMCID: PMC4450097.

Harper VM, Oh JY, Stapley R, Marques MB, Wilson L, Barnes S, Sun CW, Townes T, Patel RP. (2015) Peroxiredoxin-2 recycling is inhibited during erythrocyte storage. Antioxid Redox Signal. 22(4):294-307. PMCID: PMC4298151.

Hoyt K, Warram JM, Wang D, Ratnayaka S, Traylor A, Agarwal A. (2015) Molecular Ultrasound Imaging of Tissue Inflammation Using an Animal Model of Acute Kidney Injury. Mol Imaging Biol. 17(6):786-792. PMCID: PMC4818575.

Hull TD, Kamal AI, Boddu R, Bolisetty S, Guo L, Tisher CC, Rangarajan S, Chen B, Curtis LM, George JF, Agarwal A. (2015) Heme Oxygenase-1 Regulates Myeloid Cell Trafficking in AKI.  J Am Soc Nephrol. 26(9):2139-2151. PMCID: PMC4552119.

Jansone B, Kadish I, van Groen T, Beitnere U, Moore DR, Plotneice A, Pajuste K, Klusa V. (2015) A Novel 1,4-Dihydrophridine Derivative Improves Spatial Learning and Memory and Modifies Brain Protein Expression in Wild Type and Transgenic APPSweDI Mice. PLoS One. 10(6):e0127686. PMCID: PMC4456351.

Kramann R, Fleig SV, Schneider RK, Fabian SL, DiRocco DP, Maarouf O, Wongboonsin J, Ikeda Y, Heckl D, Chang SL, Rennke HG, Waikar SS, Humphreys BD. (2015) {harmacological GLI2 inhibition prevents myfibroblast cell-cycle progression and reduced kidney fibrosis. J Clin Invest. 125(8):2935-2951. PMCID: PMC4563736.

Kramer PA, Chacko BK, George DJ, Zhi D, Wei CC, Dell’Italia LJ, Melby SJ, George JF, Darley-Usmar VM. (2015) Decreased Bioenergetic Health Index in monocytes isolated from the pericardial fluid and blood of postoperative cardiac surgery patients. Biosci Rep. 35(4):e00237. PMCID: PMC4613711.

Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Barnes S, Arabshahi A, Dell’Italia LJ, George DJ, Steele C, George JF, Darley-Usmar VM, Melby SJ. (2015) Hemoglobin-associated oxidative stress in the pericardial compartment of postoperative cardiac surgery. Lab Invest. 95(2):132-141. PMCID: PMC4422823.

Kramer PA, Darley-Usmar VM. (2015) The emerging theme of redoc bioenergetics in health and disease. Biomed J. 38(4):294-300. Review.

Kramer PA, Prichard L, Chacko B, Ravi S, Overton ET, Heath SL, Darley-Usmar V. (2015) Inhibition of the lymphocyte metabolic switch by the oxidative burst of human neutrophils. Clin Sci (Lond.) 129(6):489-504.

Layton AT, Vallon V, Edwards A. (2015) Modeling oxygen consumption in the proximal tubule: effects of NHE and SGLT2 inhibition. Am J Physiol Renal Physiol. 308(12):F1343-F1357. PMCID: PMC4469883.

Li H, Satriano J, Thomas JL, Miyamoto S, Sharma K, Pastor-Soler NM, Hallows KR, Singh P. (2015) Interactions between HIF-1α and AMPK in the regulation of cellular hypoxia adaptation in chronic kidney disease. Am J Physiol Renal Physiol. 309(5):F414-F428. PMCID: PMC4556888.

Lopez EF, Kabarowski JH, Ingle KA, Kain V, Barnes S, Crossman DK, Lindsey ML, Halade GV. (2015) Obesity superimposed on aging magnifies inflammation and delays the resolving response after myocardial infarction. Am J Physiol Heart Circ Physiol. 308(4):H269-H280. PMCID: PMC4329482.

Michel MC, Mayoux E, Vallon V. (2015) A comprehensive review of the pharmacodynamics of the SGLT2 inhibitor empagliflozin in animals and humans. Naunyn Schmiedebergs Arch Pharmacol. 388(3):801-816. Review.

Minassian A, Maihofer AX, Baker DG, Nievergelt CM, Geyer MA, Risbrough VB, Marine Resiliency Study Team. (2015) Association of Predeployment Heart Rate Variability With Risk of Postdeployment Posttraumatic Stress Disorder in Active-Duty Marines. JAMA Psychiatry. 72(10):979-986.

Mrug M, Zhou J, Yang C, Aronow BJ, Cui X, Schoeb TR, Siegal GP, Yoder BK, Guay-Woodford LM. (2015) Genetic and Informatic Analyses Implicate Kif12 as a Candidate Gene within the Mpkd2 Locus That Modulates Renal Cystic Disease Severity in the Cys1cpk Mouse. PLoS One.10(8):e0135678. PMCID: PMC4546649.

Murthy S, Larson-Casey JL, Ryan AJ, He C, Kobzik L, Carter AB. (2015) Alternative activation of macrophages and pulmonary fibrosis are modulated by scavenger receptor, macrophage receptor with collagenous structure. FASEB J. 29(8):3527-3536. PMCID: PMC4511206.

Pang P, Jin X, Proctor BM, Farley M, Roy N, Chin MS, von Andrian UH, Vollmann E, Perro M, Hoffman RJ, Chung J, Chauhan N, Mistri M, Muslin AJ, Bonventre JV, Siedlecki AM. (2015) RGS4 inhibits angiotensis II signaling and macrophage localization during renal reperfusion injury independent of vasospasm. Kidney Int. 87(4):771-783. PMCID: PMC4382433.

RamachandraRao SP, Matthias MA, Mondrogon CK, Aghania E, Park C, Kong C, Ishaya M, Madrigal A, Horng J, Khoshaba R, Bounkhoun A, Basilico F, De Palma A, Agresta AM, Awidishu L, Naviaux RK, Vinetz JM, Mauri P. (2015) Proteomic analysis of urine exposomes reveals renal tubule response to leptospiral colonization in experimentally infected rats. PLoS Negl Trop Dis. 9(3):e0003640. PMCID: PMC4368819.

Rao F, Schork AJ, Maihofer AX, Nievergelt CM, Marcovina SM, Miller ER, Witztum JL, O’Connor DT, Tsimikas S. (2015) Heritability of Biomarkers of Oxidized Lipoproteins: Twin Pair Study. Arterioscler Thromb Vasc Biol. 35(7):1704-1711. PMCID: PMC4483152.

Ravi S, Chacko B, Kramer PA, Sawada H, Johnson MS, Zhi D, Marques MB, Darley-Usmar VM. (2015) Defining the effects of storage on platelet bioenergetics: The role of increased proton leak. Biochim Biophys Acta. 1852(11):2525-2534. PMCID: PMC4582014.

Saeidi B, Koralkar R, Griffin RL, Halloran B, Ambalavanan N, Askenazi DJ. (2015) Impact of gestational age, sex and postnatal age on urine biomarkers in premature neonates. Pediatr Nephrol. 30(11):2037-2044. PMCID: PMC4581905.

Speed JS, Fox BM, Johnston JG, Pollock DM. (2015) Endothelin and renal ion and water transport. Semin Nephrol. 35(2):137-144. PMCID: PMC4499165.

Speed JS, Heimlich JB, Hyndman KA, Fox BM, Patel V, Yanagisawa M, Pollock JS, Titze JM, Pollock DM. (2015) Endothelin-1 as a master regulator of whole-body NA+ homeostasis. FASEB J. 29(12):4937-4944. PMCID: PMC4653060.

Speed JS, Pollock DM. (2015) New clues towards solving the mystery of endothelin and blood pressure regulation. Hypertension. 66(2):275-277. PMCID: PMC4498997.

Surolia R, Karki S, Kim H, Yu Z, Kulkarni T, Mirov SB, Carter AB, Rowe SM, Matalon S, Thannickal VJ, Agarwal A, Antony VB. (2015) Heme oxyganse-1-mediated autophagy protects against pulmonary endothelial cell death and development of emphysema in cadmium-treated mice. Am J Physiol Lung Cell Mol Physiol. 309(3):L280-L292. PMCID: PMC4525122.

Vallon V. (2015) The mechanisms and therapeutic potential of SGLT2 inhibitors in diabetes mellitus. Annu Rev Med. 66:255-270. Review.

Wall SB, Oh JY, Mitchell L, Laube AH, Campbell SL, Renfrow MB, Landar A. (2015) Rac1 modification by an electrophilic 15-deoxy delta(12,14)-prostaglandin J2 analog. Redox Biol. 4:346-354. PMCID: PMC4326178.

Warnock DG, Powell TC, Donnelly JP, Wang HE. (2015) Categories of Hospital-Associated Acute Kidney Injury: Time Course of Changes in Serum Creatinine Values. Nephron. 131(4):227-236. PMCID: PMC4698143.

Wells JM, Jackson PL, Viera L, Bhatt SP, Gautney J, Handley G, King RW, Xu X, Gaggar A, Bailey WC, Dransfield MT, Blalock JE. (2015) A randomized, Placebo-controlled Trial of Roflumilast. Effect on Proline-Gylcine-Proline and neutrophilic Inflammation in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 192(8):934-942. PMCID: PMC4642210.

Yadav P, Leung N, Sanders PW, Cockwell P. (2015) the use of immunoglobulin light chain assays in the diagnosis of paraprotein-related kidney disease. Kidney Int. 87(4):692-697. PMCID: PMC4863638.

Zhang K, Mir SA, Hightower CM, Miramontes-Gonzalez JP, Maihofer AX, Chen Y, Mahata SK, Nievergelt CM, Schork NJ, Freedman BI, Vaingankar SM, O’Connor DT. (2015) Molecular Mechanism for Hypertensive Renal Disease: Differential Regulation of Chromogranin A Expression at 3’-Untranslated Region Polymorphism C+87T by MicroRNA-107. J Am Soc Nephrol. 26(8):1816-1825. PMCID: PMC4520173.


Abdul Roda M, Sadik M, Gaggar A, Hardison MT, Jablonsky MJ, Braber S, Blalock JE, Redegeld FA, Folkerts G, Jackson PL. (2014) Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation. PLoS One. 9(5):e97594. PMCID: PMC4023971.

Andringa KK, Agarwal A. (2014) Role of hypoxia-inducible factors in acute kidney injury. Nephron Clin Pract. 127(1-4):70-74. Review.

Billings FT 4th, Shaw AD. (2014) Clinical trial endpoints in acute kidney injury. Nephron Clin Pract. 127(1-4):89-93. PMCID: PMC4480222.

Blantz RC. Phenotypic charateristics of diabetic kidney involvement. Kidney Int. 86(1):7-9. PMCID: PMC4076684.

Blantz RC, Singh P. (2014) Glomerular and tubular function in the diabetic kiney. Adv Chronic Kidney Dis. 21(3):297-303. Review.

Borsting E, Patel SV, Decleves AE, Lee SJ, Rahman QM, Akira S, Satriano J, Sharma K, Vallon V, Cunard R. (2014) Tribbles Homolog 3 Attenuates Mammalian Target of Rapamycin Complex-2 Signaling and Inflammation in the Diabetic Kidney. J Am Soc Nephrol. 25(9):2067-2078. PMCID: PMC4147976.

Bowling CB, Muntner P, Sawyer P, Sanders PW, Kutner N, Kennedy R, Allman RM. (2014) Community mobility among older adults with reduced kidney function: a study of life-space. Am J Kidney Dis. 63(3):429-436. PMCID: PMC3943884.

Chacko BK, Kramer PA, Ravi S, Benavides GA, Mitchell T, Dranka BP, Ferrick D, Singal AK, Ballinger SW, Bailey SM, Hardy RW, Zhang J, Zhi D, Darley-Usmar VM. (2014) The Bioenergetic Health Index: a new concept in mitochondrial translational research. Clin Sci (Lond). 127(6):367-373. PMCID: PMC4202728.

Claure-Del Granado R, Macedo E, Soroko S, Kim Y, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2014) Anticoagulation, delivered dose and outcomes in CRRT: The program to improve care in acute renal disease (PICARD). Hemodial Int. 18(3):641-649. PMCID: PMC4220040.

Decleves AE, Sharma K, Satriano J. (2014) Beneficial Effects of AMP-Activated Protein Kinase Agonists in Kidney Ischemia-Reperfusion: Autophagy and Cellular Stress Markers.  Nephron Exp Nephrol. PMCID: PMC4458239.

Edwards A, Castrop H, Laghmani K, Vallon V, Layton AT. (2014) Effects of NKCC2 isoform regulation on NaCl transport in thick ascending limb and macula densa: a modeling study. Am J Physiol Renal Physiol. 307(2):F137-F146. PMCID: PMC4101627.

Feng W,Chumley P, Allon M, George J, Scott DW, Patel RP, Litovsky S,Jaimes EA. (2014) The transcription factor E26 transformation-specific sequence-1 mediates neointima formation in arteriovenous fistula. J Am Soc Nephrol.25(3):475-87. PMCID: PMC3935588.

Fenton RA, Murray F, Dominguez Rieg JA, Tang T, Levi M, Rieg T. (2014) Renal Phosphate Wasting in the Absence of Adenylyl Cyclase 6. J Am Soc Nephrol. 25(12):2822-2834. PMCID: PMC4243352.

Fu Y, Vallon V. (2014) Mineralcorticoid-induced sodium appetite and renal salt rentention: evidence for sommon signaling and effector mechanisms. Nephron Physiol. 128(1-2):8-16. PMCID: PMC4275376.

Hovater MB, Ying WZ, Agarwal A, Sanders PW. (2014) Nitric oxide and carbon monoxide antagonize TGF-β through ligand-independent internalization of TβR1/ALK5. Am J Physiol Renal Physiol. 307(6):F727-F735. PMCID: PMC4166728.

Hull TD, Agarwal A. (2014) Bilirubin: a potential biomarker and therapeutic target for diabetic nephropathy. Diabetes. 63(8):2613-2616. PMCID: PMC4113062.

Hull TD, Agarwal A, George JF. (2014) The mononuclear phagocyte system in homeostasis and disease: a role for heme oxygenase-1. Antioxid Redox Signal. 20(11):1770-1788. PMCID: PMC3961794.

Inampudi C, Parvataneni S, Morgan CJ, Deedwania P, Fonarow GC, Sanders PW, Prabhu SD, Butler J, Forman DE, Aronow WS, Allman RM, Ahmed A. (2014) Spironolactone use and higher hospital readmission for Medicare beneficiaries with heart failure, left ventricular ejection fraction <45%, and estimated glomerular filtration rate <45 ml/min/1.73 m(2.). Am J Caridol. 114(1):79-82. PMCID: PMC4169696.

Judd EK, Calhoun DA, Warnock DG. (2014) Pathophysiology and treatment of resistant hypertension: the role of aldosterone and amiloride-sensitive sodium channels. Semin Nephrol. 34(5):532-539. PMCID: PMC4450367.

Kasimsetty SG, DeWolf SE, Shigeoka AA, McKay DB. (2014) Regulation of TLR2 and NLRP3 in primary murine renal tubular epithelial cells. Nephron Clin Pract. 127(1-4):119-123. PMCID Journal - In Process.

Kramer PA, Chacko BK, Ravi S, Johnson MS, Mitchell T, Darley-Usmar VM. (2014) Bioenergetics and the oxidative burst: protocols for the isolation and evaluation of human leukocytes and platelets. J Vis Exp. (85). PMCID: PMC4089433.

Kramer PA, Ravi S, Chacko B, Johnson MS, Darley-Usmar VM. (2014) A review of the mitochondrial and glycolytic metabolism in human platelets and leukocytes: Implication for their use as bioenergetics biomarkers. Redox Biol. 2:206-210. PMCID: PMC3909784.

Kumar R, Vallon V. (2014) Reduced renal calcium excretion in the absence of sclerostin expression: evidence for a novel calcium-regulating bone kidney axis. J Am Soc Nephrol. 25(10):2159-2168. PMCID: PMC4178449.

Mahoney M, Sorace A, Warram J Samuel S, Hoyt K. (2014) Volumetric contrast-enhanced ultrasound imaging of renal perfusion. J Ultrasound Med. 33(8):1427-1437. PMCID: PMC4135386.

Masuda T, Fu Y, Equchi A, Czogalla J, Rose MA, Kuczkowski A, Gerasimova M, Feldstein AE, Scadeng M, Vallon V. (2014) Dipeptidyl peptidase IV inhibitor lowers PPARγ agonist-induced body weight gain by affecting food intake, fat mass, and beige/brown fat but not fluid retention. Am J Physiol Endocrinol Metab. 306(4):E388-E398. PMCID: PMC3923087.

McKnight K, Hoang HD, Prasain JK, Brown N, Vibbert J, Hollister KA, Moore R, Ragains JR, Reese J, Miller MA. (2014) Neurosensory perception of environmental cues modulates sperm motility critical for fertilization. Science. 344(6185):754-757. PMCID: PMC4094289.

Mehta RL, Kellum JA. (2014) Targeting recovery from acute kidney injury: executive summary from the round table conference at the 19th International Conference on Continuous Renal Replacement Therapies (Manchester Grand Hyatt, San Diego, Calif., USA, March 2-3 2014). Nephron Clin Pract. 127(1-4):1-3. PMCID: PMC4220039.

Mehta RL, Sanders PW, Agarwal A. (2014) Changing paradigms in acute kidney injury: from mechanisms to management – proceedings of the 5th annual UAB-UCSD O’Brien Center Symposiu (San Diego, Calif., USA, March 4, 2014). Nephron Clin Pract. 127(1-4):117-118. PMCID: PMC4309370.

Murray PT, Mehta RL, Shaw A, Ronco C, Endre Z, Kellum JA, Chawla LS, Cruz D, Ince C, Okusa MD, ADQI 10 Workgroup. (2014) Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative Consensus Conference. Kidney Int. 85(3):513-521. PMCID: PMC4198530.

Nourbakhsh N, Singh P. (2014) Role of renal oxygenation and mitochondrial function in the pathophysiology of acute kidney injury. Nephron Clin Pract. 127(1-4):149-152. Review.

Pasha DN, Davis JT, Rao F, Chen Y, Wen G, Fung MM, Mahata M, Zhang K, Trzebinska D, Mutapic M, Hightower CM, Lipokowitz MS, Ji M, Ziegler MG, Nievergelt CM, O’Connor DT. (2014) Heritable influence of DBH on adrenergic and renal function: twin and disease studies. PLoS One. 8(12):e82956. PMCID: PMC3876991.

Portilla D. (2014) Apoptosis, fibrosis and senescence. Nephron Clin Pract. 127(1-4):65-69. Review.

Rangarajan S, Sunil B, Fan C, Wang PX, Cutter G, Sanders PW, Curtis LM. (2014) Distinct populations of label-retaining cells in the adult kidney are defined temporally and exhibit divergent regional distributions. Am J Physiol Renal Physiol. 307(11):F1274-F1282. PMCID: PMC4254969.

Ravi S, Mitchell T, Kramer PA, Chacko B, Darley-Usmar VM. (2014) Mitochondria in monocytes and macrophages-implications for translational and basic research. Int J Biochem Cell Biol. 53C:202-207. PMCID: PMC4111987.

Reily C, Ueda H, Huang ZQ, Mestecky J, Julian BA, Willey CD, Novak J. (2014) Cellular signaling and production of glalctose-deficiant IgA1 in IgA nephropathy, an autoimmune disease. J Immunol Res. 2014:197548. PMCID: PMC4134797.

Rieg T, Kohan DE. (2014) Regulation of nephron water and electrolyte transport by adenylyl cyclases. Am J Physiol Renal Physiol. 306(7):F701-F709. PMCID: PMC3962601.

Rieg T,Masuda T,Gerasimova M,Mayoux E,Platt K,Powell DR,Thomson SC,Koepsell H,Vallon V. (2014) Increase in SGLT1-mediated transport explains renal glucose reabsorption during genetic and pharmacological SGLT2 inhibition in euglycemia. Am J Physiol Renal Physiol. 306(2):F188-F193. PMCID: PMC3920019

Singh P,Thomson SC. (2014) Salt sensitivity of tubuloglomerular feedback in the early remnant kidney.Am J Physiol Renal Physiol. 306(2):F172-F180. PMCID: PMC3920016.

Vallon V. (2014) Do tubular changes in the diabetic kidney affect the susceptibility to acute kidney injury? Nephron Clin Pract. 127(1-4):133-138. Review.

Vallon V, Docherty NG. (2014) Intestinal regulation of urinary sodium excretion and the pathophysiology of diabetic kidney disease: a focus on glucagon-like peptide 1 and dipeptidyl peptidase 4. Exp Physiol. 99(9):1140-1145. PMCID: PMC4162767.

Vallon V,Gerasimova M, Rose MA, Masuda T, Satriano J, Mayoux E, Koepsell H, Thomson SC, Rieg T. (2014) SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol. 306(2):F194-F204. PMCID: PMC3920018.

Virk-Baker MK, Barnes S, Krontiras H, Nagy TR. (2014) S-(-) equol producing status not associated with breast cancer risk among low isoflavone-consuming US postmenopausal women undergroing a physician-recommended breast biopsy. Nutr Res. 34(2):116-125.  PMCID: PMC4028846.

Wall SB, Smith MR, Ricart K, Zhou F, Vayalil PK, Oh JY, Landar A. (2014) Detection of electrophile-sensitivie proteins. Biochim Biophys Acta. 1840(2):913-922. PMCID: PMC3858512.

Wetta LA, Biggio JR, Cliver S, Abramovici A, Barnes S, Tita AT. (2014) Is midtrimester vitamin D status associated with spontaneous preterm birth and preeclampsia? Am J Perinatol. 31(6):541-546. PMCID: PMC4451220.

Wells JM, O’Reilly PJ, Szul T, Sullivan DI, Handley G, Garrett C, McNicholas CM, Roda MA, Miller BE, Tal-Singer R, Gaggar A, Rennard SI, Jackson PL, Blalock JE. (2014) An aberrant leukotriene A4 hydrolase-proline-glycine-proline pathway in the pathogenesis of chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 190(1):51-61. PMCID: PMC4226028.

Wilson L, Arabshahi A, Simons B, Prasain J, Barnes S. (2014) Improved high sensitivity analysis of polyphenols and their metabolites by nano-liquid chromatography-mass spectrometry. Arch Biochem Biophys. 559:3-11. PMCID: PMC4143533.

Ying WZ, Aaron KJ, Sanders PW. (2014) Sodium and potassium regulate endothelial phospholipase C-γ and Bmx. Am J Physiol Renal Physiol. 307(1):F58-F63. PMCID: PMC4080160.


Aaron KJ, Sanders PW. (2013) Role of dietary salt and potassium intake in cardiovascular health and disease: a review of the evidence. Mayo Clin Proc. 88(9):987-995. PMCID: PMC3833247.

Allen CE, Sanders PW. (2013) Hypertensive nephrosclerosis: not enough of a good thing? Am J Physiol Renal Physiol. 304(6):F674-F675. PMCID: PMC3602697.

Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Patil N, Ambalavanan N. (2013) Fluid overload and mortality are associated with acute kidney injury in sick near-term/term neonate. Pediatr Nephrol. 28(4):661-666. Non-government funded study.

Barnes S, Prasain J, Kim H. (2013) In nutrition, can we “see” what is good for us? Adv Nutr. 4(3):327S-334S. PMCID: PMC3650504.

Bhanushali GK, Jain G, Fatima H, Leisch LJ, Thornley-Brown D. (2013) AKI associated with synthetic cannabinoids: a case series. Clin J Am Soc Nephrol. 8(4):523-526. PMCID: PMC3613952.

Chacko BK, Kramer PA, Ravi S, Johnson MS, Hardy RW, Ballinger SW, Darley-Usmar VM. (2013) Methods for defining distinct bioenergetics profiles in platelets, lymphocytes, monocytes, and neutrophils, and the oxidative burst from human blood. Lab Invest. 93(6):690-700. PMCID: PMC3674307.

Clement LC*, Macé C*, Avila-Casado C, Joles JA, Kersten S, Chugh SS. (2013) Circulating angiopoietin-like 4 links proteinuria with hypertriglyceridemia in nephrotic syndrome. Nat Med. 20(1):37-46. PMCID: PMC4114723.

Cowley AW Jr, Ryan RP, Kurth T, Skelton MM, Schock-Kursch D, Gretz N. (2013) Progression of glomerular filtration rate reduction determined in conscious Dahl salt-sensitive hypertensive rats. Hypertension. 62(1):85-90. PMCID: PMC3806646.

DuPont JJ, Greaney JL, Wenner MM, Lennon-Edwards SL, Sanders PW, Farguhar WB, Edwards DG. (2013) High dietary sodium intake impairs endothelium-dependent dilation in health salt-resistant humans. J Hypertens. 31(3):530-536. PMCID Journal – In Process.

Han SM, El Oussini H, Scekic-Zahirovic J, Vibbert J, Cottee P, Prasain JK, Bellen HJ, Dupuis L, Miller MA. (2013) VAPB/AL S8 MSP ligands regulate striated muscle energy metabolism critical for adult survival in caenorhabditis. PLoS Genet. 9(9):e1003738. PMCID: PMC3764199.

Hoang HD, Prasain JK, Dorand D, Miller MA. (2013) A heterogenous mixture of F-series prostaglandins promotes sperm guidance in the Caenorhabditis elegans reproductive tract. PLoS Genet. 9(1):e1003271. PMCID: PMC3561059.

Hull TD, Bolisetty S, Dealmeida AC, Litovsky SH, Prabhu SD, Agarwal A, George JF. (2013) Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase. Lab Invest. 93(8):868-879. PMCID: PMC3729748.

Lewington AJ, Cerda J, Mehta RL. (2013) Raising awareness of acute kidney injury: a global perspective of a silent killer. Kidney Int. 84(3):457-467. PMCID: PMC3758780.

Merscher-Gomez S, Guzman J, Pedigo CE, Lehto M, Aguillon-Prada R, Mendez A, Lassenius MI, Forsblom C, Yoo T, Villarreal R, Maiguel D, Johnson K, Goldberg R, Nair V, Randolph A, Kretzler M, Nelson RG, Burke GW 3rd, Groop PH, Fornoni A, the FinnDiane Study Group. (2013) Cyclodextrin protects podocytes in diabetic kidney disease. Diabetes. 62(11):3817-3827. PMCID: PMC3806621.

Mitchell T, Johnson MS, Ouyang X, Chacko BK, Mitra K, Lei X, Gai Y, Moore DR, Barnes S, Zhang J, Koizumi A, Ramanadham S, Darley-Usmar VM. (2013) Dysfunctional mitochondrial bioenergetics and oxidative stress in Akit(+/Ins2)-derived β-cells. Am J Physiol Endocrinol Metab. 305(5):E585-E599. PMCID: PMC3761167.

Mrug M, Sanders PW. (2013) Beware the low HDAC11:males at risk for ischemic kidney injury. Am J Physiol Renal Physiol. 305(7):F973-F974. PMCID: PMC3798743.

Pacurari M, Xing D, Hilgers RH, Guo YY, Yang Z, Hage F. (2013) Endothelial cell transfusion ameloiorates endothelial dysfunction in 5/6 nephrectomized rats.Am J Physiol Heart Circ Physiol. 305(8):H1256-H1264. PMCID: PMC3798787.

Pegues MA, McCrory MA, Zarjou A, Szalai AJ. (2013) C-reactive protein exacerbates renal ischemia-reperfusion injury. Am J Physiol Renal Physiol. 304(11): F1358-F1365. PMCID: PMC3680688.

Prasain JK, Arbshahi A, Taub PR, Sweeney S, Moore R, Sharer JD, Barnes S. (2013) Simultaneous quantification of F2-isoprostanes and prostaglandins in human urine by liquid chromatography tandem-mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 913-914:161-168. PMCID: PMC3779072.

Prasain JK, Hoang HD, Edmonds JW, Miller MA. (2013) Prostaglandin extraction and analysis in Caenorhabditis elegans. J Vis Exp. (76). PMCID: PMC3728984

Reily C, Mitchell T, Chacko BK, Benavides G, Murphy MP, Darley-Usmar V. (2013) Mitochondrially targeted compounds and their impact on cellular bioenergetics. Redox Biol. 1(1):86-93. PMCID: PMC3647698.

Rieg T. (2013) A high-throughput method for measurement of glomerular filtration rate in conscious mice. J Vis Exp. 75:e50330. PMCID: PMC3679673.

Rieg T, Dominguez Rieg J. (2013) Connecting type A intercalated cell metabolic state to V-ATPase function: phosphorylation does matter! Am J Physiol Renal Physiol. 305(8):F1105-F1106. PMCID: PMC3798730.

Santriano J, Sharma K. (2013) Autophagy and metabolic changes in obesity-related chronic kidney disease. Nephrol Dial Transplant. 28 Suppl4:iv29-iv36. PMCID: PMC3814227.

Santriano J, Sharma K, Blantz RC, Deng A. (2013) Induction of AMPK activity corrects early pathophysiological alterations in the subtotal nephrectomy model of chronic kidney disease. Am J Physiol Renal Physiol. 305(5):F727-F733. PMCID: PMC3761200.

Sawant A, Schafer CC, Jin TH, Zmijewski J, Tse HM, Roth J, Sun Z, Siegal GP, Thannickal VJ, Ponnazhagan S, Deshane J. (2013) Enhancement of antitumor immunity in lung cancer by targeting myeloid-derived suppressor cell pathways. Cancer Res. 72(22):6609-6620. PMCID: PMC3854493.

Sharma N, Malarkey EB, Berbari NF, O’Connor AK, Vanden Heuvel GB, Mrug M, Yoder BK. (2013) Proximal tubule proliferation is insufficient to induce rapid cyst formation after cilia disruption. J Am Soc Nephrol. 24(3):456-464. PMCID: PMC3582198.

Shimamura M, Seleme MC, Guo L, Saunders U, Schoeb TR, George JF, Britt WJ. (2013) Ganciclovir prophylaxis improves late murine cytomegalovirus induced renal allograft damage. Transplantation. 95(1):48-53. PMCID: PMC3700407.

Singh P, Ricksten SE, Bragadottir G, Redfors B, Nordquist L. (2013) Renal Oxygenation and haemodynamics in acute kidney injury and chronic kidney disease. Clin Exp Pharmacol Physiol. 40(2):138-147. PMCID: PMC3710120.

Taler SJ, Agarwal R, Bakris GL, Flynn JT, Nilsson PM, Rahman M, Sanders PW, Textor SC, Weir MR, Townsend RR. (2013) KDOQI US Commentary on the 2012 KDIGO Clinical practice guideline for management of blood pressure in CKD. Am J Kidney Dis. 62(2):201-213. PMCID: PMC3929429.

Tolwani A. (2013) Continuous Renal Replacement Therapy for Acute Kidney Injury. N Engl J Med. 368(12):1160-1161. Commentary

Wang HE, Gaurav J, Glassock RJ, Warnock DG. (2013) Comparison of Absolute Serum Creatinine Changes versus KDIGO Consensus Definitions for Characterizing Stages of Acute Kidney Injury. Nephrol Dialy Transplant. 28(6):1447-1454. PMCID: PMC3685303.

Ying WZ, Aaron KJ, Sanders PW. (2013) Transforming growth factor-β regulates endothelial function during high salt intake in rats. Hypertension. 62(5):951-956. PMCID: PMC3972137.

Zarjou A, Bolisetty S, Joseph R, Traylor A, Apostolov EO, Arosio P, Balla J, Verlander J, Darshan D, Kuhn LC, Agarwal A. (2013) Proximal tubule H-ferritin mediates iron trafficking in acute kidney injury. J Clin Invest. 123(10):4423-4434. PMCID: PMC3784534.


Ahmed A, Fonarow GC, Zhang Y, Sanders PW, Allman RM, Arnett DK, Feller MA, Love TE, Aban IB, Levesque R, Ekundayo OJ, Dell'Italia LJ, Bakris GL, Rich MW. (2012) Renin-angiotensin inhibition in systolic heart failure and chronic kidney disease. Am J Med. 125(4):399-410. PMCID: PMC3324926

Askenazi DJ, Selewski DT, Paden ML, Cooper DS, Bridges BC, Zappitelli M, Fleming GM. (2012) Renal Replacement Therapy in Critically Ill Patients Receiving Extracorporeal Membrane Oxygenation. Clin J Am Soc Nephrol. 7(8):1328-1326. Review.

Askenazi DJ, Koralkar R, Hundley HE, Montesanti A, Parwar P, Sonjara S, Ambalavanan N. (2012) Urine Biomarkers Predict Acute Kidney Injury in Newborns. J Pediatr. 161(2):270-275. PMCID: PMC3598122.

Askenazi DJ. (2012) Do children with acute kidney injury require long-term evaluation for CKD? Am J Kidney Dis. 59(4):478-480. Commentary.

Blantz RC, Singh P, Deng A, Thomson SC, Vallon V. (2012) Acute Saline Expansion Increases Nephron Filtration and Distal Flow Rate but Maintains Tubuloglomerular Feedback Responsiveness: Role of Adenosine A1 Receptors. Am J Physiol Renal Physiol. 303(3):F405-F411. PMCID: PMC3433865

Bolisetty S, Traylor A, Zarjou A, Johnson MS, Benavides GA, Ricart K, Boddu R, Moore RD, Landar A, Barnes S, Darley-USmar V, Agarwal A. (2013) Mitochondria-targeted heme oxygenase-1 decreases oxidative stress in renal epithelial cells. Am J Physiol Renal Physiol. 305(3):F255-F264. PMCID: PMC3742869.

Borsting E, Cheng VP, Glass CK, Vallon V, Cunard R. (2012) Peroxisome proliferator-activated receptor-γ agonists repress epithelial sodium channel expression in the kidney. Am J Physiol Renal Physiol. 302(5):F540-F551. PMCID: PMC3353644

Bowling CB, Sanders PW, Allman RM, Rogers WJ, Patel K, Aban IB, Rich MW, Pitt B, White M, Bakris GC, Fonarow GC, Ahmed A. (2012) Effects of enalapril in systolic heart failure patients with and without chronic kidney disease: Insights from the SOLVD Treatment trial. Int J Cardiol. 167(1):151-156. PMCID: PMC3395757.

Cutter GR. (2012) Statistical cures and other fallacies. Mult Scler. 18(4):387-390. Review.

Dawoud D, Lyndon W, Mrug S, Bissler JJ, Mrug M. (2012) Impact of ultrasound-guided kidney biopsy simulation on trainee confidence and biopsy outcomes. Am J Nephrol, 36(6):570-574. PMCID: PMC3918883.

Feng W, Chumley P, Hua P, Rezonzew G, Jaimes D, Duckworth MW, Xing D, Jaimes EA. (2012) Role of the Transcription factor Erythroblastosis Virus E26 Oncogen Homolog-1 (ETS-1) as Mediator of the Renal Proinflammatory and Profibrotic Effects of Angiotensin II. Hypertension. 60(5):1226-1233. PMC Journal – In Process.

Fleming GM, Askenazi DJ, Bridges BC, Cooper DS, Paden ML, Selewski DT, Zappitelli M. (2012) A Multicenter International Survey of Renal Supportive Therapy During ECMO: The Kidney Intervention During Extracorporeal Membrane Oxygenation (KIDMO) Group. ASAIO J. 58(4):407-414. PMC Journal - In Process.

Giordano S, Lee J, Darley-Usmar VM, Zhang J. (2012) Distinct effects of rotenone, 1-methyl-4-phenylpyridinium and 6-hydroxydopamine on cellular bioenergetics and cell death. PLoS One. 7(9):e44610. PMCID: PMC3435291.

Gorboulev V, Schürmann A, Vallon V, Kipp H, Jaschke A, Klessen D, Friedrich A, Scherneck S, Rieg T, Cunard R, Veyhl-Wichmann M, Srinivasan A, Balen D, Breljak D, Rexhepaj R, Parker HE, Gribble FM, Reimann F, Lang F, Wiese S, Sabolic I, Sendtner M, Koepsell H. (2012) Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion. Diabetes. 61(1):187-196. PMCID: PMC3237647.

Granado CD, Macedo E, Chertow GM, Soroko S, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2012) Toward the optimal dose metric in continuous renal replacement therapy. Int J Artif Organs. 35(6):413-424. PMC Journal - In Process.

Guo L, Agarwal A, George JF. (2012) Orthotopic Aortic Transplantation in Mice for the Study of Vascular Disease. J Vis Exp. 28(69):e4338. PMCID: PMC3565855.

Higdon AN, Benavides GA, Chacko BK, Ouyang X, Johnson MS, Landar A, Zhang J, Darley-Usmar VM. (2012) Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy. Am J Physiol Heart Circ Physiol. 302(7):H1394-H1409. PMCID: PMC3330785.

Hua P, Feng W, Rezonzew G, Chumley P, Jaimes EA. (2012) The transcription factor ETS-1 regulates angiotensin II-stimulated fibronectin production in mesangial cells. Am J Physiol Renal Physiol. 302(11) F1418-F1429. PMC Journal - In Process.

Hull TD, Bolisetty S, DeAlmeida AC, Litovsky SH, Prabhu SD, Agarwal A, George JF. (2013) Heme oxygenase-1 expression protects the heart from acute injury caused by inducible Cre recombinase. Lab Invest. 93(8):868-879. PMCID: PMC3729748.

Jetton JG, Askenazi DJ. (2012) Update on acute kidney injury in the neonate. Curr Opin Peditar. 24(2):191-196. Review.

Kanbay M, Bayram Y, Solak Y, Sanders PW. (2013) Dietary potassium: a key mediator of the cardiovascular response to ditary sodium chloride. J Am Soc Hypertens. 7(5):395-400. PMCID Journal – In Process.

Kelpke SS, Chen B, Bradley K, Teng X, Chumley P, Moore B, Head H, Viera L, Thompson JA, Crossman DK, Bray MS, Eckhoff DE, Agarwal A, Patel RP. (2012) Sodium nitrite therapy protects against brain death induced kidney injury and improves post-transplantation outcomes. Kidney Int. 82(3):304-313. PMCID: PMC3412933.

Kennedy RE, Schneider LS, Cutter GR. (2012) Biomarker Positive and Negative Subjects in the ADNI Cohort: Clinical Characterization. Curr Alzheimer Res. 9(10):1135-1141. PMC Journal - In Process.

Kim J, Zarjou A, Traylor AM, Hull TD, Jaimes EA, George JF, Mikhail FM, Agarwal A. (2012) In vivo regulation of the heme oxygenase-1 gene in humanized transgenic mice. Kidney Int. 82(3):278-291. PMCID: PMC3396739.

Kwon M, Pavlov TS, Nozu K, Rasmussen SA, Ilatovskaya DV, Lerch-Gaggl A, North LM, Kim H, Qian F, Sweeney WE Jr, Avner ED, Blumer JB, Staruschenko A, Park F. (2012) G-protein signaling modulator 1 deficiency accelerates cystic disease in an orthologous mouse model of autosomal dominant polycystic kidney disease. Proc Natl Acad Sci USA. 109(52):21462-21467. PMCID: PMC3535663.

Lang F, Vallon V. (2012) Serum- and glucocorticoid-inducible kinase 1 in the regulation of renal and extrarenal potassium transport. Clin Exp Nephrol. 16(1):73-80. Review

McClure M, DeLucas LJ, Wilson L, Ray M, Rowe SM, Wu X, Dai Q, Hong JS, Sorscher EJ, Kappes JC, Barnes S. (2012) Purification of CFTR for mass spectrometry analysis: identification of palmitoylation and other post-translational modifications. Protein Eng Des Sel. 25(1):7-14. PMCID: PMC3276306.

Mehta, RL: (2012) Acute kidney injury: AKI in acute myocardial infarction-are we making progress? Nat Rev Nephrol. 8(6):322-323. Review.

Mitchell T, Darley-Usmar V. (2012) Metabolic syndrome and mitochondrial dysfunction: insights from preclinical studies with a mitochondrially targeted antioxidant. Free Radic Biol Med. 52(5):838-840. Review/Commentary.

Moskowitz-Kassai E, Mackelaite L, Chen J, Patel K, Dadhania DM, Gross SS, Chander P, Delaney V, Deng L, Chen L, Cui X, Suthanthiran M, Goligorsky MS. (2012) Excretion of anti-angiogenic proteins in patients with chronic allograft dysfunction. Nephrol Dial Transplant. 27(2):494-497. PMCID: PMC3275786.

Pan F, Goh JW, Cutter G, Su W, Pleimes D, Wang C. (2012) Long-Term Cost-Effectiveness Model of Interferon Beta-1b in the Early Treatment of Multiple Sclerosis in the United States. Clin Ther. 34(9):1966–1976. PMC Journal - In Process.

Perianayagam MC, Tighiouart H, Liangos O, Kuznetsov D, Wald R, Rao F, O’Connor DT, Jaber B. (2012) Polymorphisms in the Myeloperoxidase Gene Locus and Acute Kidney Injury: A Two-Step Genetic Association Study. Kidney Int. 82(8):909-919. PMCID: PMC3461107.

Rezonzew G, Chumley P, Feng W, Hua P, Siegal G, Jaimes EA. (2012) Nicotine exposure and the progression of chronic kidney disease: role of the 7-nicotine acetylcholine receptor. Am J Physiol Renal Physiol. 303(2):F304–F312. PMCID: PMC3404588.

Saag KG, Mohr PE, Esmail L, Mudano AS, Wright N, Beukelman T, Curtis JR, Cutter G, Delzell E, Gary LC, Harrington TM, Karkare S, Kilgore ML, Lewis CE, Moloney R, Oliveira A, Singh JA, Warriner A, Zhang J, Berger M, Cummings SR, Pace W, Solomon DH, Wallace R, Tunis SR. (2012) Improving the efficiency and effectiveness of pragmatic clinical trials in older adults in the United States. Contemp Clin Trials. 33(6):1211-1216. PMCID: PMC3675785.

Sabolic I, Vrhovac I, Eror DB, Gerasimova M, Rose M, Breljak D, Ljubojevic M, Brzica H, Sebastiani A, Thal SC, Sauvant C, Kipp H, Vallon V, Koepsell H. (2012) Expression of Na+-D-glucose cotransporter SGLT2 in rodents is kidney-specific and exhibits sex and species differences. Am J Physiol Cell Physiol. 302(8):C1174-C1188. PMC Journal - In Process.

Sanders PW. (2012) Mechanisms of light chain injury along the tubular nephron. J Am Soc Nephrol. 23(11):1777-1781. Review

Schoeb TR, Jarmi T, Hicks JM, Henke S, Zarjou A, Hitoshi S, Kramer P, Novak J, Agarwal A, Bullard DC. (2012) eNOS inhibits the development of autoimmune-mediated vasculitis. Arthritis Rheum. 64(12):4114-4124. PMCID: PMC3510336.

Singh P, Blantz RC, Rosenberger C, Gabbai FB, Schoeb TR, Thomson SC. (2012) Aberrant tubuloglomerular feedback and HIF-1α confer resistance to ischemia after subtotal nephrectomy. J Am Soc Nephrol. 23(3):483-493. PMCID: PMC3294306.

Susantitaphong P, Perianayagam MC, Kang SW, Zhang W, Rao F, O’Connor DT, Jaber BL. (2012) Association of functional kallikrein-1 promoter polymorphisms and acute kidney injury: a case-control and longitudinal cohort study. Nephron Clin Pract. 122(3-4):107-113. PMCID: PMC3700581.

Tan CK, Carey AJ, Cui X, Webb RI, Ipe D, Crowley M, Cripps AW, Benjamin WH Jr, Ulett KB, Schembri MA, Ulett GC. (2012) Genome-wide mapping of cystitis due to Streptococcus agalactiae and Escherichia coli in mice identifies a unique bladder transcriptome that signifies pathogen-specific antimicrobial defense against urinary tract infection. Infect Immun. 80(9):3145-3160. PMCID: PMC3418756.

Taub PR, Borden K, Fard A, Maisel AS. (2012) Role of biomarkers in the diagnosis and prognosis of acute kidney injury in patients with the cardiorenal syndrome. Expert Rev Cardiovasc Ther. 10(5) 657-667: Review

Teerlink JR, Iragui VJ, Mohr JP, Carson PE, Hauptman PJ, Lovett DH, Miller AB, Piña IL, Thomson S, Varosy PD, Zile MR, Cleland JG, Givertz MM, Metra M, Ponikowski P, Voors AA, Davison BA, Cotter G, Wolko D, Delucca P, Salerno CM, Mansoor GA, Dittrich H, O'Connor D, Massie BM. (2012) The safety of an adenosine A(1)-receptor antagonist, rolofylline, in patients with acute heart failure and renal impairment: findings from PROTECT. Drug Saf. 35(3):233-244. PMC Journal - In Process.

Thomson SC, Rieg T, Miracle C, Mansoury H, Whaley J, Vallon V, Singh P. (2012) Acute and chronic effects of SGLT2 blockade on glomerular and tubular function in the early diabetic rat. Am J Physiol Regul Integr Comp Physiol. 302(1):R75-R83. PMCID: PMC3349378.

Toney GM, Vallon V, Stockand JD. (2012) Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na(+) channel. Curr Opin Nephrol Hypertens. 21(1):52-60. Review.

Vallon V, Eraly SA, Ramachandra Rao S, Gerasimova M, Rose M, Nagle M, Anzai N, Smith T, Sharma K, Nigam SK, Rieg T. (2012) A role for the organic anion transporter OAT3 in renal creatinine secretion in mice. Am J Physiol Renal Physiol. 302(10):F1293-F1299. PMCID: PMC3362066.

Vallon V, Thomson SC. (2012) Renal function in diabetic disease models: the tubular system in the pathophysiology of the diabetic kidney. Annu Rev Physiol. 74:351-375. Review.

Wall SB, Oh JY, Diers AR, Landar A. (2012) Oxidative modification of proteins: an emerging mechanism of cell signaling. Front Physiol.3:369. PMCID: PMC3442266.

Wang HE, Muntner P, Chertow GM, Warnock DG. (2012) Acute kidney injury and mortality in hospitalized patients. Am J Nephrol. 35(4):349-355. PMCID: PMC3362180.

Ying WZ, Aaron KJ, Sanders PW. (2012) Effect of agingand dietary salt and potassium intake on endothelial PTEN (Phosphatase and tensin homolog on chromosome 10) function. PLoS ONE. 7(11):e41785. PMCID: PMC3492426.

Ying WZ, Allen CE, Curtis LM, Aaron KJ, Sanders PW. (2012) Mechanism and prevention of acute kidney injury from cast nephropathy in a rodent model. J Clin Invest. 122(5):1777-1785. PMCID: PMC3336971.

Ying WZ, Wang PX, Sanders PW. (2012) Pivotal role of apoptosis signal-regulating kinase 1 in monoclonal free light chain-mediated apoptosis. Am J Pathol. 180(1):41-47. PMCID: PMC3338338.

Zarjou A, Sanders PW, Mehta RL, Agarwal A. (2012) Enabling innovative translational research in acute kidney injury. Clin Transl Sci. 5(1):93-101. PMCID: PMC3292183.

Zarjou A, Agarwal A. (2012) Heme oxygenase-1 as a target for TGF-β in kidney disease. Semin Nephrol. 32(3):277-286. PMCID: PMC3407376

Zarjou A, Guo L, Sanders PW, Mannon RB, Agarwal A, George JF. (2012) A reproducible mouse model of chronic allograft nephropathy with vasculopathy. Kidney Int. 82(11):1231-1235. PMCID: PMC3495090.

Zhou J, Ouyang X, Schoeb TR, Bolisetty S, Cui X, Mrug S, Yoder BK, Johnson MR, Szalai AJ, Mrug M. (2012) Kidney Injury Accelerates Cystogenesis via Pathways Modulated by Heme Oxygenase and Complement. J Am Soc Nephrol. 23(7):1161-1171. PMCID: PMC3380643.


Aaron KJ, Campbell RC, Judd SE, Sanders PW, Muntner P. (2011) Association of dietary sodium and potassium intakes with albuminuria in normal-weight, overweight, and obese participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study. Am J Clin Nutr. 94(4):1071-1078. PMCID: PMC3173025.

Anderson JT, Zeng M, Li Q, Stapley R, Moore DR 2nd, Chenna B, Fineberg N, Zmijewski J, Eltoum IE, Siegal GP, Gaggar A, Barnes S, Velu SE, Thannickal VJ, Abraham E, Patel RP, Lancaster JR Jr, Chaplin DD, Dransfield MT, Deshane JS. (2011) Elevated levels of NO are localized to distal airways in asthma. Free Radic Biol Med. 50(11):1679-1688. PMCID: PMC3124865.

Askenazi DJ, Koralkar R, Levitan EB, Goldstein SL, Devarajan P, Khandrika S, Mehta RL, Ambalavanan N. (2011) Baseline values of candidate urine acute kidney injury biomarkers vary by gestational age in premature infants. Pediatr Res. 70(3):302-306. PMCID: PMC3152663.

Bell PD, Fitzgibbon W, Sas K, Stenbit AE, Amria M, Houston A, Reichert R, Gilley S, Siegal GP, Bissler J, Bilgen M, Chou PC, Guay-Woodford L, Yoder B, Haycraft CJ, Siroky B. (2011) Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis. J Am Soc Nephrol. 22(5):839-848. PMCID: PMC3083306.

Blantz RC, Singh P. (2011) Analysis of the Prerenal Contributions to Acute Kidney Injury. Contrib Nephrol. 174:4-11. Review.

Bolisetty S, Agarwal A. (2011) Urine albumin as a biomarker in acute kidney injury. Am J Physiol Renal Physiol. 300(3):F626-F627. PMCID: PMC3064133.

Bowling CB, Feller MA, Mujib M, Pawar PP, Zhang Y, Ekundayo OJ, Aban IB, Love TE, Sanders PW, Anker SD, Fonarow GC, Ahmed A. (2011) Relationship between stage of kidney disease and incident heart failure in older adults. Am J Nephrol. 34(2):135-141. PMCID: PMC3136373.

Buckoreelall K, Wilson L, Parker WB. (2011) Identification and characterization of two adenosine phosphorylase activities in Mycobacterium smegmatis. J Bacteriol. 193(20):5668-5674. PMCID: PMC3187226.

Clement LC, Avila-Casado C, Macé C, Soria E, Bakker WW, Kersten S, Chugh SS. (2011) Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat Med. 17(1):117-122. PMCID: PMC3021185.

Dranka BP, Benavides GA, Diers AR, Giordano S, Zelickson BR, Reily C, Zou L, Chatham JC, Hill BG, Zhang J, Landar A, Darley-Usmar VM. (2011) Assessing bioenergetic function in response to oxidative stress by metabolic profiling. Free Radic Biol Med. 51(9):1621-1635. PMCID: PMC3548422.

Du Y, Zappitelli M, Mian A, Bennett M, Ma Q, Devarajan P, Mehta R, Goldstein SL. (2011) Urinary biomarkers to detect acute kidney injury in the pediatric emergency center. Pediatr Nephrol. 26(2):267-274. PMC Journal – In Process.

Filippatos GS, Ahmed MI, Gladden JD, Mujib M, Aban IB, Love TE, Sanders PW, Pitt B, Ankar SD, Ahmed A. (2011) Hyperuricaemia, chronic kidney disease, and outcomes in heart failure: potential mechanistic insights from epidemiological data. Eur Heart J. 32(6):712-720. PMCID: PMC3056205.

Floyd KA, Stella DR, Wang CC, Laurentz S, McCabe GP, Srivastava OP, Barnes S. (2011) Genistein and genistein-containing dietary supplements accelerate the early stages of cataractogenesis in the male ICR/f rat. Exp Eye Res. 92(2):120-127. PMCID: PMC3034771.

Granado CD, Macedo E, Soroko S, Chertow GM, Himmelfarb J, Ikizler AT, Paganini EP, Mehta RL. (2011) Effluent volume in continuous renal replacement therapy overestimates the delivered dose of dialysis. Clin J Am Soc Nephrol. 6(3):467-475. PMCID: PMC3082402.

Granado CD, Mehta RL. (2011) Withholding and withdrawing renal replacement support in AKI. Semin Dial. 24(2):208-214. Review

Granado CD, Mehta RL. (2011) Assessing and delivering dialysis dose in AKI. Semin Dial. 24(2):157-163. Review.

Horikawa YT, Panneerselvam M, Kawaraguchi Y, Tsutsumi YM, Ali SS, Balijepalli RC, Murray F, Head BP, Niesman IR, Rieg T, Vallon V, Insel PA, Patel HH, Roth DM. (2011) Cardiac-specific overexpression of caveolin-3 attenuates cardiac hypertrophy and  increases natriuretic peptide expression and signaling. J Am Coll Cardiol. 57(22):2273-2283. PMCID: PMC3236642.

Hutchison CA, Batuman V, Behrens J, Bridoux F, Sirac C, Dispenzieri A, Herrera GA, Lachmann H, Sanders PW. (2011) International Kidney and Monoclonal Gammopathy Research Group. The pathogenesis and diagnosis of acute kidney injury in multiple myeloma. Nat Rev Nephrol. 8(1):43-51. PMCID: PMC3375610.

Kanbay M, Chen Y, Solak Y, Sanders PW. (2011) Mechanisms and consequences of salt sensitivity and dietary salt intake. Curr Opin Nephrol Hypertens. 20(1):37-43. PMCID: PMC3089903.

Kang SW, Shih PA, Mathew RO, Mahata M, Biswas N, Rao F, Yan L, Bouchard J, Malhotra R, Tolwani A, Khandrika S, Mehta RL, O'Connor DT. (2011) Renal kallikrein excretion and epigenetics in human acute kidney injury: Expression, mechanisms and consequences. BMC Nephrol. 12:27. PMCID: PMC3154145.

Lee SA, Belyaeva OV, Wu L, Kedishvili NY. (2011) Retinol dehydrogenase 10 but not retinol/sterol dehydrogenase(s) regulates the expression of retinoic acid-responsive genes in human transgenic skin raft culture. J Biol Chem. 286(15):13550-13560. PMCID: PMC3075701.

Li FJ, Kubagawa Y, McCollum MK, Wilson L, Motohashi T, Bertoli LF, Barton JC, Barnes S, Davis RS, Kubagawa H. (2011) Enhanced levels of both the membrane-bound and soluble forms of IgM Fc receptor (FcμR) in patients with chronic lymphocytic leukemia. Blood. 118(18):4902-4909. PMCID: PMC3208298.

Li F, Glinskii OV, Zhou J, Wilson LS, Barnes S, Anthony DC, Glinsky VV. (2011) Identification and analysis of signaling networks potentially involved in breast carcinoma metastasis to the brain. PLoS One. 6(7) e21977. PMCID: PMC3136937.

Lu A, Miao M, Schoeb, TR, Agarwal A, Murphy-Ullrich JE. (2011) Blockade of TSP1-dependent TGF-β activity reduces renal injury and proteinuria in a murine model of diabetic nephropathy. Am J Pathol. 178(6):2573-2586. PMCID: PMC3124297.

Macedo E, Malhotra R, Claure-Del Granado R, Fedullo P, Mehta RL. (2011) Defining urine output criterion for acute kidney injury in critically ill patients. Nephrol Dial Transplant. 26(2):509-515. PMCID: PMC3108356.

Mehta RL. (2011) Management of acute kidney injury: it's the squeaky wheel that gets the oil! Clin J Am Soc Nephrol. 6(9):2102-2104. Review.

Mehta RL, Bouchard J, Soroko S, Ikizler TA, Paganini EP, Chertow GM, Himmelfarb J. (2011) Sepsis as a Cause and Consequence of Acute Kidney Injury: Program to Improve Care in Acute Renal Disease (PICARD). Intensive Care Med. 37(2):241-248. PMCID: PMC3028102.

Mehta RL. (2011) Biomarker explorations in acute kidney injury: the journey continues. Kidney Int. 80(4):332-334. Review.

Perianayagam MC, Tighiouart H, Nievergelt CM, O'Connor DT, Liangos O, Jaber BL. (2011) CYBA Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury: A Prospective Cohort Study. Nephron Extra. 1(1):112-123. PMCID: PMC3290849.

Rajbhandari R, Peng N, Moore R, Arabshahi A, Wyss JM, Barnes S, Prasain JK. (2011) Determination of cranberry phenolic metabolites in rats by liquid chromatography-tandem mass spectrometry. J Agric Food Chem. 59(12):6682-6688. PMCID: PMC3165050.

Rieg T, Gerasimova M, Boyer JL, Insel PA, Vallon V. (2011) P2Y2‚ receptor activation decreases blood pressure and increases renal Na+ excretion. Am J Physiol Regul Integr Comp Physiol. 301(2):R510-R518. PMCID: PMC3154711

Sanders PW. (2011) Light chain-mediated tubulopathies. Contrib Nephrol. 169:262-269. Review.

Shimamura M, Saunders U, Rha B, Guo L, Cassady KA, George JF, Britt WJ. (2011) Ganciclovir transiently attenuates murine cytomegalovirus-associated renal allograft inflammation. Transplantation. 92(7):759-766. PMC Journal – In Process.

Singh P, Okusa MD. (2011) Role of Tubuloglomerular Feedback in the Pathogenesis of AKI. Controversies in Acute Kidney Injury. Contrib Nephrol. 174:12-21. Invited review.

Sweeney DE, Vallon V, Rieg T, Wu W, Gallegos TF, Nigam SK. (2011) Functional Maturation of Drug Transporters in the developing, neonatal and postnatal Kidney. Mol Pharmacol. 80(1):147-154. PMCID: PMC3127534.

Thomson SC, Blantz RC. (2011) Biophysical basis of glomerular filtration. In Seldin and Giebisch’s The Kidney: Physiology and Pathophysiology, Fifth Edition, Alpern RJ, Caplan M, and Moe OW (Eds) In Press 2011.  Book Chapter.

Thomson SC, Blantz RC. (2011) Glomerular filtration rate. In Comprehensive Physiology.  Pollack DM, Garvin J (eds), In Press, 2011. Book Chapter.

Vallon V, Komers R. (2011) Pathophysiology of the diabetic kidney. Comp Physiol. 1(3):1175-1232. Review.

Vallon V, Platt KA, Cunard R, Schroth J, Whaley J, Thomson SC, Koepsell H, Rieg T. (2011) SGLT2 mediates glucose reabsorption in the early proximal tubule. J Am Soc Nephrol. 22(1):104-112. PMCID: PMC3014039

Vallon V, Rieg T. (2011) Regulation of renal NaCl and water transport by the ATP/UTP/P2Y2 receptor system. Am J Physiol Renal Physiol. 301(3):F463-F475. PMCID: PMC3174559.

Vallon V, Thomson S. (2011) Anomalous role for dietary salt in diabetes mellitus? Nat Rev Endocrinol.7(7):377-378. PMCID: PMC3335262.

Vallon V. (2011) The proximal tubule in the pathophysiology of the diabetic kidney. Am J Physiol Regul Integr Comp Physiol. 300(5):R1009-R1022. PMCID: PMC3094037

Vallon V. (2011) Molecular determinants of renal glucose reabsorption focus on “Glucose transport by human renal Na+-d-glucose co-transporters SGLT1 & SGLT2”. Am J Physiol Cell Physiol. 300(1):C6-C8. PMCID: PMC3023181.

Weigent DA. (2011) High molecular weight isoforms of growth hormone in cells of the immune system. Cell Immunol. 271(1):44-52. PMC Journal – In Process.

Wu QQ, Wang Y. Senitko M, Meyer C, Wigley CW. Ferguson DA, Grossman E, Chen J, Zhou ZJ, Hartono J, Winterberg P. Chen B, Agarwal A, Lu CY. (2011) Bardoxolone Methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes - Nrf2, PPARγ, and HO-1. Am J Physiol Renal Physiol. 300(5):F1180-F1192. PMCID: PMC3094059.

Ying WZ, Wang PX, Aaron KJ, Basnayake K, Sanders PW. (2011) Immunoglobulin light chains activate nuclear factor-β in renal epithelial cells through a Src-dependent mechanism. Blood. 117(4):1301-1307. PMCID: PMC3056473.

Zarjou, A, Agarwal A. (2011) Sepsis and acute kidney injury. J Am Soc Nephrol. 22(6):999-1006. Review.

Zarjou A, Kim J, Traylor AM, Sanders PW, Balla J, Agarwal A, Curtis LM. (2011) Paracrine effects of mesenchymal stem cells in cisplatin-induced renal injury require heme oxygenase-1. Am J Physiol Renal Physiol. 300(1):F254-F262. PMCID: PMC3023217.

Zarjou A, Yang S, Abraham E, Agarwal A, Liu G. (2011) Identification of a microRNA signature in renal fibrosis: Role of miR21. Am J Physiol Renal Physiol. 301(4):F793-F801. PMCID: PMC3191802.

Zavaczki E, Jeney V, Agarwal A, Zarjou A, Oros M, Katko M, Varga Z, Balla G, Balla J. (2011) Hydrogen sulfide inhibits the calcification and osteoblastic differentiation of vascular smooth muscle cells. Kidney Int. 80(7):731-739. PMCID: PMC3257044.

Zhang Y, Fonarow GC, Sanders PW, Farahmand F, Allman RM, Aban IB, Love TE, Levesque R, Kilgore ML, Ahmed A. (2011) A propensity-matched study of the comparative effectiveness of angiotensin receptor blockers versus angiotensin-converting enzyme inhibitors in heart failure patients age ≥ 65 years. Am J Cardiol. 108(10):1443-1448. PMCID: PMC3324944.

Zheng Y, Qin H, Frank SJ, Deng L, Litchfield DW, Tefferi A, Pardanani A, Lin  FT, Li J, Sha B, Benveniste EN. (2011) A CK2-dependent mechanism for activation of the JAK-STAT signaling pathway. Blood. 118(1):156-166. PMCID: PMC3139382.


Alam A, O'Connor DT, Perianayagam MC, Kolyada AY, Chen Y, Rao F, Mahata M, Mahata S, Liangos O, Jaber BL. (2010) Phenylethanolamine N-Methyltransferase Gene Polymorphisms and Adverse Outcomes in Acute Kidney Injury. Nephron Clin Pract. 114(4):c253-c259. PMCID: PMC2865401.

Basnayake K, Ying WZ, Wang PX, and Sanders P. (2010) Immunoglobulin Light Chains Activate Tubular Epithelial Cells Through Redox Signaling. J Am Soc Nephrol. 21(7):1165-1173. PMCID: PMC3152234.

Bhatnagar V, Garcia EP, O’Connor DT, Brophy VH, Alcaraz J, Richard E, Bakris GL, Middleton JP, Norris KC, Wright J, Hiremath L, Contreras G, Appel LJ, Lipkowitz MS, AASK Study Investigators. (2010) CYP3A4 and CYP3A5 Polymorphisms and Blood Pressure Response to Amlodipine among African-American Men and Women with Early Hypertensive Renal Disease. Am J Nephrol. 31(2):95-103. PMCID: PMC2853591.

Bolisetty S, Traylor AM, Kim J, Joseph R, Ricart K, Landar A, Agarwal A. (2010) Heme oxygenase-1 inhibits renal tubular macroautophagy in acute kidney injury. J Am Soc Nephrol. 21(10):1702-1712. PMCID: PMC3013546.

Bouchard J, Macedo E, Mehta RL. (2010) Dosing of Renal Replacement Therapy in Acute Kidney Injury: Lessons Learned From Clinical Trials. Am J Kidney Dis. 55(3):570-579. Review.

Bouchard J, Macedo E, Soroko S, Chertow GM, Himmelfarb J, Ikizler TA, Paganini EP, Mehta RL. (2010) Comparison of methods for estimating glomerular filtration rate in critically ill patients with acute kidney injury. Nephrol Dial Transplant. 25(1):102-107. PMCID: PMC2910324.

Bouchard J, Mehta RL. (2010) Fluid Balance Issues in the Critically Ill Patient. Contrib Nephrol. 164:69. Review.

Bowling CB, Pitt B, Ahmed MI, Aban IB, Sanders PW, Mujib M, Campbell RC, Love TE, Aronow WS, Allman RM, Bakris GL, Ahmed A. (2010) Hypokalemia and outcomes in patients with chronic heart failure and chronic kidney disease: findings from propensity-matched studies. Circ Heart Fail. 3(2):253-260. PMCID: PMC2909749.

Chacko BK, Reily C, Srivastava A, Johnson MS, Ulasova E, Agarwal A, Zinn KR, Murphy MP, Kalyanaraman B, Darley-Usmar V. (2010) Prevention of diabetic nephropathy in the Ins2+/-Akita J mice by the mitochondria-targeted therapy Mito-Q. Biochem J. 432(1):9-19. PMCID: PMC2973231.

Chen Y, Lipkowitz MS, Salem RM, Fung MM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Hicks PJ, Bowden DW, Freedman BI, O’Connor DT. (2010) Progression of chronic kidney disease (CKD): Adrenergic genetic influence on GFR decline in hypertensive nephrosclerosis. Am J Nephrol. 32(1):23-30. PMCID: PMC2914391.

Chen Y, Rao F, Wen G, Gayen JR, Zhang K, Vaingankar SM, Biswas N, Mahata M, Friese RS, Fung MM, Salem RM, Nievergelt C, Bhatnagar V, Hook VY, Ziegler MG, Mahata SK, Hamilton BA, O’Connor DT. (2010) Naturally occurring genetic variants in human chromogranin A (CHGA) associated with hypertension as well as hypertensive renal disease. Cell Mol Neurobiol. 30(8):1395-1400. PMCID: PMC3008929.

Chen Y, Salem RM, Rao F, Fung MM, Bhatnagar V, Pandey B, Mahata M, Waalen J, Nievergelt CM, Lipkowitz MS, Hamilton BA, Mahata SK, O'Connor DT. (2010) Common charge-shift mutation Glu65Lys in K+ channel β1‚ -Subunit KCNMB1: pleiotropic consequences for glomerular filtration rate and progressive renal disease. Am J Nephrol. 32(5):414-424. PMCID: PMC2975731

Deng A, Arndt MA, Satriano J, Singh P, Rieg T. (2010) Renal Protection in Chronic Kidney Disease: Hypoxia Inducible Factor Activation Versus Angiotensin II Blockade. Am J Physiol Renal Physiol. 299:(6):F1365-F1373.  PMCID: PMC3006314.

Deshane J, Kim J, Bolisetty S, Hock TD, Hill-Kapturczak N, Agarwal A. (2010) Sp1 regulates chromatin looping between an intronic enhancer and distal promoter of the human heme oxygenase-1 gene in renal cells. J Biol Chem. 285(22):16476-16486. PMCID: PMC2878004.

Diers AR, Higdon AN, Ricart KC, Johnson MS, Agarwal A, Kalyanaraman B, Landar A, Darley-Usmar VM. (2010) Mitochondrial targeting of the electrophilic lipid 15-deoxy-Delta12, 14-prostaglandin J2 increases apoptotic efficacy via redox cell signalling mechanisms. Biochem J. 426(1):31-41. PMCID: PMC3079364.

Edmonds JW, Prasain JK, Dorand D, Yang Y, Hoang HD, Vibbert J, Kubagawa HM, Miller MA. (2010) Insulin/FOXO signaling regulates ovarian prostaglandins critical for reproduction. Dev Cell. 19(6):858-871. PMCID: PMC3026445.

Fogo AB, Bostad L, Svarstad E, Molls S, Barbey F, Geldenhuys L, West M, Ferluga D, Vujkovac B, Howie AJ, Burns A, Waldek S, Noel LH, Grunfeld JP, Valbuena C, Oliveira JP, Muller J, Brunig F, Zhang X, Warnock WG. (2010) Scoring system for renal pathology in Fabry disease: report of the International Study Group of Fabry Nephropathy (ISGFN). Nephrol Dial Transplant. 25(7):2168-2177. PMCID: PMC2902894.

George J, Agarwal A. (2010) Hydrogen: another gas with therapeutic potential. Kidney Int. 77(2):85-87. Review.

Hellman NE, Liu Y, Merkel E, Austin C, Le Corre S, Beier DR, Sun Z, Sharma N, Yoder BK, Drummond IA. (2010) The zebrafish foxj1a transcription factor regulates cilia function in response to injury and epithelial stretch. Proc Natl Acad Sci USA. 107(43):18499-18504. PMCID: PMC2972951.

Higdon AN, Dranka BP, Hill BG, Oh JY, Johnson MS, Landar A, Darley-Usmar VM. (2010) Methods for imaging and detecting modification of proteins by reactive lipid species. Free Radic Biol Med. 47(3):201-212. PMCID: PMC2727357.

Lang F, Huang DY, Vallon V. (2010) SGK, renal function and hypertension. J Nephrol. 23 Suppl 16:S124-S129. Review

Macedo E, Bouchard J, Soroko SH, Chertow GM, Himmelfarb J, Ikizker TA, Paganini EP. Mehta RL. (2010) Fluid accumulation, recognition and staging of acute kidney injury in critically-ill patients. Crit Care. 14(3):R82. PMCID: PMC2911707.

Macedo E, Mehta RL. (2010) Early vs Late start of dialysis: it’s all about timing. Crit Care. 14(1):112. PMCID: PMC2875487.

Macedo E, Mehta RL. (2010) Prerenal Azotemia in Congestive Heart Failure. Contrib Nephrol. 164:79-87. Review.

Mehta RL. (2010) Timed and targeted therapy for acute kidney injury: a glimpse of the future. Kidney Int. 77(11):947-949. Review.

Mrug M, Bissler J. (2010) Simulation of real-time ultrasound-guided renal biopsy. Kidney Int. 78(7):705-707. PMCID: PMC3420353.

Parks DJ, Agarwal A, George JF. (2010) Heme oxygenase-1 Expression in murine dendritic cell subpopulations: Effect on CD8+ dendritic cell differentiation in vivo. Am J Pathol. 176(6):2831-2839. PMCID: PMC2877844.

Pochynyuk O, Rieg T, Bugaj V, Schroth J, Fridman A, Boss GR, Insel PA, Stockand JD, Vallon V. (2010) Dietary Na+ inhibits the open probability of the epithelial sodium channel in the kidney by enhancing apical P2Y2 receptor tone. FASEB J. 24(6):2056-2065. PMCID: PMC2874475.

Rieg T, Tang T, Murray F, Schroth J, Insel PA, Fenton RA, Hammond HK, Vallon V. (2010) Adenylate cyclase 6 determines cAMP formation and aquaporin-2 phosphorylation and trafficking in renal inner medulla. J Am Soc Nephrol. 21(12):2059-2068. PMCID: PMC3014019.

Rodriguez-Flores JL, Zhang K, Kang SW, Wen G, Ghosh S, Friese RS, Mahata SK, Subramaniam S, Hamilton BA, O’Connor DT. (2010) Conserved regulatory motifs at phenylethanolamine N-methyltransferase (PNMT) are disrupted by common functional genetic variation: an integrated computational/ experimental approach. Mamm Genome. 21(3-4):195-204. PMCID: PMC2844968.

Salem RM, O’Connor DT, Schork NJ. (2010) Curve-Based Multivariate Distance Matrix Regression (CMDMR) Analysis: Application to Genetic Association Analyses Involving Repeated Measures. Physiol Genomics. 42(2):236-247. PMCID: PMC3032281.

Sanders PW, Agarwal A. (2010) Acute Kidney Injury. ACP Medicine, A textbook of Medicine published by the American College of Physicians. Editor-in-chief – Elizabeth G. Nabel, MD. Decker Intellectual Properties, Hamilton, ON L8N 3K7, Canada. Book Chapter

Satriano J, Mansoury H, Deng A, Sharma K, Vallon V, Blantz RC, Thomson SC. (2010) Transition of kidney tubule cells to a senescent phenotype in early experimental diabetes. Am J Physiol Cell Physiol. 299(2):C374-C380. PMCID: PMC2928628.

Singh P, Rifkin DE, Blantz RC. (2010) Chronic kidney disease: an inherent risk factor for acute kidney injury? Clin J Am Soc Nephrol. 5(9):1690-1695. Review.

Singh P, Thomson SC. (2010) Renal homeostasis and tubuloglomerular feedback. Curr Opin Nephrol Hypertens. 19(1):59-64. Review.

Snelgrove RJ, Jackson PL, Hardison MT, Noerager BD, Kinloch A, Gaggar A, Shastry S, Rowe SM, Shim YM, Hussell T, Blalock JE. (2010) A critical role for LTA4H in limiting chronic pulmonary neutrophilic inflammation. Science. 330(6000):90-94. PMCID: PMC3072752.

Thomson SC, Blantz RC. (2010) A new role for charge of the glomerular capillary membrane. J Am Soc Nephrol. 21(12):2011-2013. Review.

Vallon V, Sharma K. (2010) Sodium-glucose transport: role in diabetes mellitus and potential clinical implications. Curr Opin Nephrol Hyperten. 19(5):425-431. Review.

Zhou J, Ouyang X, Cui X, Schoeb TR, Smythies LE, Johnson MR, Guay-Woodford LM, Chapman AB, Mrug M. (2010) Renal CD14 expression correlates with the progression of cystic kidney disease. Kidney Int. 78(6):550-560. PMCID: PMC3422025.


Arndt MA, Battaglia V, Parisi E, Lortie MJ, Isome M, Baskerville C, Pizzo DP, Ientile R, Colombatto S, Toninello A, Satriano J. (2009) The arginine metabolite agmatine protects mitochondrial function and confers resistance to cellular apoptosis. Am J Physiol Cell Physiol. 296(6):C1411-C1419. PMCID: PMC2692420.

Bolisetty S, Agarwal A. (2009) Neutrophils and acute kidney injury: Not neutral any more. Kidney Int. 75(7):674-676. Review.

Bouchard J, Mehta RL. (2009) Volume management in continuous renal replacement therapy. Semin Dial. 22(2):146-150. Review.

Bouchard J, Mehta RL. (2009) Fluid accumulation and acute kidney injury: consequence or cause. Curr Opin Crit Care. 15(6):509-513. Review.

Chen B, Guo L, Fan C, Bolisetty S, Joseph R, Wright MM, Agarwal A, George J. (2009) Carbon monoxide rescues heme oxygenase-1 deficient mice from arterial thrombosis in allogenic aortic transplantation. Am J Pathol. 175(1):422-429. PMCID: PMC2708827.

Chen Y, Mahata M, Rao F, Khandrika S, Courel M, Fung MM, Zhang K, Stridsberg M, Ziegler MG, Hamilton BA, Lipkowitz MS, Taupenot L, Nievergelt C, Mahata SK, O’Connor DT. (2009) Chromogranin A Regulates Renal Function by Triggering Weibel-Palade Body Exocytosis. J Amer Soc Nephrol. 20(7):1623-1632. Topic of editorial. PMCID: PMC2709688.

Cui X, Zhou J, Qiu J, Johnson MR, Mrug M. (2009) Validation of endogenous internal real-time PCR controls in renal tissues. Am J Nephrol. 30(5):413-417. PMCID: PMC2818397

Deng A, Tang T, Singh P, Wang C, Satriano J, Thomson S, Blantz RC. (2009) Regulation of oxygen utilization by angiotensin II in chronic kidney disease. Kidney Int. 75:197-204. PMCID: PMC3151651.

Friese RS, Rao F, Khandrika S, Thomas BG, Ziegler MG, Schmid-Schonbein GW, O'Connor DT. (2009) Matrix metalloproteinases: Discrete elevations in essential hypertension and hypertensive end-stage renal disease. Clin Exp Hypertens. 31(7):521-533. PMCID: PMC2875383.

Fung MM, Chen Y, Lipkowitz MS, Salem RM, Bhatnagar V, Mahata M, Nievergelt CM, Rao F, Mahata SK, Schork NJ, Brophy VH, O’Connor DT, for the AASK co-investigators. (2009) Adrenergic Beta-1 Receptor Genetic Variation Predicts Longitudinal Rate Of GFR Decline In Hypertensive Nephrosclerosis. Nephrol Dial Transplant. 24(12):3677-3686. PMCID: PMC2790952.

Fung MM, O'Connor DT. (2009) Complex renal traits: role of adrenergic genetic polymorphism. J Am Soc Nephrol. 20(6):1172-1174. Review.

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