Gene Siegal, M.D., Ph.D., the inaugural Robert W. Mowry Endowed Professor and Executive Vice Chair, retired on December 31, 2024, after 34 years of service in the UAB Department of Pathology.
Patients with multiple myeloma often develop bone lesions resulting in skeletal-related events (SREs), such as spinal cord compression, vertebral collapse, pathologic fractures and bone pain. Bone lesions are caused by increases in osteoclast formation and are treated using antiresorptive drugs such as denosumab. This drug is an antibody that combats RANKL, a critical regulator of osteoclast formation, however, its use suppresses the immune system and increases the risk of serious infections.
Xu Feng, Ph.D., a professor in the UAB Department of Pathology’s Division of Molecular and Cellular Pathology, is working to develop a better targeting strategy.
Sixto Leal Jr., M.D., Ph.D., Division Director, Laboratory Medicine, has been named the Jay M. McDonald Endowed Professor in Experimental Pathology, effective January 1, 2025.
The Department of Pathology is thrilled to announce a new faculty member joining our team January 1. Natalie R. Gassman, Ph.D., joins the Division of Molecular and Cellular Pathology, led by Rakesh Patel, Ph.D., as an associate professor.
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