Dr. Angela Carter

Instructor

Areas of Interest
neuroendocrine tumorigenesis and pathophysiology, tumor-derived hormonal induction of gastrointestinal disease, bioengineering microbial-based therapeutics, host-microbe interactions

Biography

Dr. Carter is an instructor in the Gastrointestinal Surgery Division of the Department of Surgery at UAB. She received a B.S. in Biology and Chemistry from Southeastern Oklahoma State University and a Ph.D. in Cellular Signaling, with an emphasis in Pharmacology, from the University of Texas Southwestern Medical Center. Her doctoral work was performed in the laboratory of Dr. Paul Sternweis where she studied regulatory mechanisms of GTPases, delineating contributions of catalytic activation versus subcellular localization. Dr. Carter’s postdoctoral work was funded by the American Cancer Society and focused on identifying biomarkers with the capacity to predict tumor response to select targeted therapeutics and the development of novel animal models of neuroendocrine cancer. Dr. Carter’s current research interests involve delineating tumorigenic signaling pathways, studying mechanisms of hormone/neurotransmitter release and engineering symbiotic organisms for therapeutic use.

Selected Publications

Grubbs EG, Gill AJ, Robinson B, Gillardon F, Reddy S, Jaskula-Sztul R, Mobley JA, Mukhtar MS, Tasciotti E, Chen H, Bibb JA. Phosphoprotein-based biomarkers as predictors for cancer therapy. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18401-18411. doi: 10.1073/pnas.2010103117. Epub 2020 Jul 20. PubMed PMID: 32690709; PubMed Central PMCID: PMC7414192.

Carter AM, Gutowski S, Sternweis PC. Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs). J Biol Chem. 2014 Jul 11;289(28):19737-46. doi: 10.1074/jbc.M114.564930. Epub 2014 May 22. PubMed PMID: 24855647; PubMed Central PMCID: PMC4094083.

Education

Undergraduate Studies

A.A. in Biological Science and Zoology
Carl Albert State College

B.S. in Biology and Chemistry
Southeastern Oklahoma State University

Graduate Studies
Ph.D. in Cell Signalling
University of Texas Southwestern Medical Center

Postdoctoral Fellowship
The University of Alabama at Birmingham

Contact

Campus Address
THT 1028G

Phone
(205) 975-7920

Email
angelamcarter@uabmc.edu