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Grams Jayleen General

Vice Chair, VA Affairs
Associate Chief of Staff, VA Surgical Services
Director, Minimally Invasive Surgery at Birmingham VA
Assistant Program Director, Minimally Invasive Surgery Fellowship

Areas of Interest
foregut and bariatric surgery, achalasia, gastroesophageal reflux disease, hiatal or paraesophageal hernias, morbid obesity and metabolic syndrome, role of the microbiome in obesity, outcomes research


Dr. Jayleen Grams joined the faculty at the University of Alabama at Birmingham in 2009. A native of Minnesota, Grams received her undergraduate degree from St. Cloud State University and matriculated into the Medical Scientist Training Program at UAB. Here, she completed her Ph.D. in biochemistry and molecular biology and her M.D. in 2003. She returned to Minnesota to complete a general surgery residency at the Mayo Clinic in Rochester, Minn., followed by a fellowship in minimally invasive surgery at Mount Sinai Hospital in New York, N.Y. Dr. Grams’ clinical practice focuses on foregut and bariatric surgery. She is also involved in an active research program as a surgeon-scientist and the education of medical students, surgery residents, and minimally invasive surgery fellows. She serves as the assistant MIS fellowship director. She is the current chair of the Resident and Fellows Education Committee for the Society of Surgeons of the Alimentary Tract.

Selected Publications

TH Pham, CW Iqbal, J Grams, AE Zarroug, J Wall, MB Ishitani, DM Nagorney, CR Moir. Outcomes of primary liver cancer in children: an appraisal of an institutional experience. (2007) J Pediatr Surg 42:834-839.

J Grams, SH Teh, VE Torres, JC Andrew, DM Nagorney. IVC stenting: a safe and effective treatment for intractable ascites in patients with polycystic liver disease. (2007) J Gastrointest Surg 11:985-990.

AM Hanna, TH Pham, JR Askegard-Giesmann, JM Grams, C Iqbal, PL Stavlo, C Moir. Outcome of adrenocortical tumors in children. (2008) J Pediatr Surg 43:843-849.

SQ Nguyen, J Grams, W Tong, AA Sabnis, DM Herron. Laparoscopic Roux-en-Y gastric bypass after previous Nissen fundoplication. (2009) Surg Obes Relat Dis 5:280-282.

JR Askegard-Giesmann, JM Grams, AM Hanna, CW Iqbal, S Teh, CR Moir.  Minimally invasive Heller myotomy in children: safe and effective. (2009) J Pediatr Surg 44:909-911.

W Tong, J Grams, D Herron.  Laparoscopic Revision of Biliopancreatic Diversion with Duodenal Switch and Management of Postoperative Obstruction. (2010) Surg Obes Relat Dis 6:96-98.

J Grams, W Tong, AJ Greenstein, B Salky.  Comparison of Intracorporeal versus Extracorporeal Anastomosis in Laparoscopic Hemicolectomy. (2010) Surg Endosc 24:1886-91.

R Shen, G Meng, C Ochsenbauer, P Clapham, J Grams, L Novak, J Kappes, L Smythies, PD Smith.  Stromal down-regulation of macrophage CD4/CCR5 expression and NF-kB activation mediates HIV-1 non-permissiveness in intestinal macrophages. (2011)  PLoS Pathog 7:e1002060.

D Bimczok, JM Grams, RD Stahl, KB Waites, LE Smythies, and PD Smith.  Stromal regulation of human gastric dendritic cells restricts the Th1 response to H. pylori. (2011) Gastroenterology 141: 929-938.

M Maricevich, J Grams, P Abell-Aleff, C Inwards, SR Jacobson.  Mediastinal silicone lymphadenopathy secondary to a ruptured breast implant. (2011) The Breast Journal 6: 674-675. 

J Hunter, R Stahl, M Kakade, I Breitman, J Grams, RH Clements.  Effectiveness of thoracoscopic truncal vagotomy in the treatment of marginal ulcers after laparoscopic Roux-en-Y gastric bypass. (2012) Am Surg 78: 663-668.

A Obeid, J Long, M Kakade, RH Clements, R Stahl, and J Grams.  Laparoscopic Roux-en-Y gastric bypass: long term clinical outcomes. (2012) Surg Endosc 26:3515-3520.

LK Altom, RJ Deierhoi, J Grams, J Richman, CC Vick, KM Itani, WG Henderson, MT Hawn. Adherence to SCIP venous thromboembolism performance measures does not improve rates of postoperative events. (2012) Am J Surg 204:591-597.

D Bimczok, LE Smythies, KB Waites, JM Grams, RD Stahl, PJ Mannon, SP Sugandha, CM Wilcox, PR Harris, S Das, PB Ernst, PD Smith.  H. pylori infection inhibits phagocyte clearance of apoptotic gastric epithelial cells. (2013) J Immunol 190:6626-6634.

A Obeid, M Breland, R Stahl, RH Clements, J Grams. Internal hernia after laparoscopic Roux-en-Y gastric bypass. (2014) J Gastrointest Surg 18:250-256.

HS Hill, J Grams, RG Walton, J Liu, DR Moellering, WT Garvey.  Carboxylated and uncarboxylated forms of osteocalcin directly modulate the glucose transport system and inflammation in adipocytes. (2014) Horm Metab Res 46:341-347.

D Bimczok, J Kao, M Zhang, S Cochrun, P Mannon, S Peter, C Wilcox, K Mönkemüller, P Harris, J Grams, R Stahl, P Smith. Human gastric epithelial cells contribute to gastric immune regulation by providing retinoic acid to dendritic cells. (2014) Mucosal Immunol 8:533-544. doi: 10.1038/mi.2014.86

AA Gullick, LA Graham, J Richman, M Kakade, R Stahl, J Grams. Association of race and socioeconomic status with outcomes following laparoscopic Roux-en-Y gastric bypass. (2015) Obes Surg 25:705-711. doi: 10.1007/s11695-014-1447-z

J Grams, WT Garvey. Weight loss and the prevention and treatment of type 2 diabetes using lifestyle therapy, pharmacotherapy, and bariatric surgery: mechanisms of action. (2015) Curr Obes Rep 4:287-302. doi: 10.1007/sl13679-015-0155-x

L Fang, F Guo, L Zhou, R Stahl, J Grams. Adipocyte morphology of subcutaneous and visceral fat depots is associated with type 2 diabetes mellitus in humans. (2015) Adipocyte 0:0,1-7. doi: 10.1080/21623945.2015.1034920

L Fang, K Kojima, L Zhou, DK Crossman, JA Mobley, J Grams. Analysis of the human proteome in subcutaneous and visceral fat depots in diabetic and nondiabetic patients with morbid obesity. (2015) J Proteomics Bioinform 8:133-141. doi: 10.4172/jpb.1000361


Medical School
University of Alabama at Birmingham

Mayo Clinic

Mount Sinai Hospital


Campus Address

Patient Appointments and Questions: 205-975-3000
Academic Office: 205-934-8047