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Dr. Angela Carter

Assistant Professor

Areas of Interest
host microbe interactions, mechanisms of microbial regulation of substance use disorders, bioengineering microbial-based therapeutics, hormonal and metabolic syndromes and disease

Biography

Dr. Carter is an assistant professor in the Division of Surgical Oncology in the Department of Surgery at UAB. She received a B.S. in Biology and Chemistry from Southeastern Oklahoma State University and a Ph.D. in Cellular Signaling, with an emphasis in Pharmacology, from the University of Texas Southwestern Medical Center. Her doctoral work was performed in the laboratory of Dr. Paul Sternweis where she studied regulatory mechanisms of GTPases, delineating contributions of catalytic activation versus subcellular localization. Dr. Carter’s postdoctoral work was funded by the American Cancer Society and focused on identifying biomarkers with the capacity to predict tumor response to select targeted therapeutics and the development of novel animal models of neuroendocrine cancer. Dr. Carter’s current research involves delineating the underlying molecular mechanisms that constitute relationships between microbes and hosts and leveraging those mechanisms toward the treatment of human disease.

Selected Publications

Shekar, A., Mabry, S. J., Cheng, M. H., Aguilar, J. I., Patel, S., Zanella, D., Saleeby, D. P., Zhu, Y., Romanazzi, T., Ulery-Reynolds, P., Bahar, I., Carter, A. M., Matthies, H. J. G., & Galli, A. (2023). Syntaxin 1 Ser14 phosphorylation is required for nonvesicular dopamine release. Science advances, 9(2), eadd8417. PubMed PMID: 36630507; PubMed Central PMCID: PMC9833662.

Grubbs EG, Gill AJ, Robinson B, Gillardon F, Reddy S, Jaskula-Sztul R, Mobley JA, Mukhtar MS, Tasciotti E, Chen H, Bibb JA. Phosphoprotein-based biomarkers as predictors for cancer therapy. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18401-18411. doi: 10.1073/pnas.2010103117. Epub 2020 Jul 20. PubMed PMID: 32690709; PubMed Central PMCID: PMC7414192.

Carter AM, Gutowski S, Sternweis PC. Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs). J Biol Chem. 2014 Jul 11;289(28):19737-46. doi: 10.1074/jbc.M114.564930. Epub 2014 May 22. PubMed PMID: 24855647; PubMed Central PMCID: PMC4094083.

Education

Undergraduate Studies

A.A. in Biological Science and Zoology
Carl Albert State College

B.S. in Biology and Chemistry
Southeastern Oklahoma State University

Graduate Studies
Ph.D. in Cell Signalling
University of Texas Southwestern Medical Center

Postdoctoral Fellowship
The University of Alabama at Birmingham

Contact

Campus Address
THT 1028G

Phone
(205) 975-7920

Email
angelamcarter@uabmc.edu