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Displaying items by tag: department of medicine

Tuberculosis kills 1.8 million people a year, and 10 million more are infected. Development of host-cell directed therapies that could restore cellular function during M. tuberculosis infection, such as a “release and kill” strategy, could shorten drug treatment of TB patients.
Abnormal antibody production that allows inflammation leading to AIDS is detected by analysis of antibodies in gut fluid of HIV-1-infected people.
In another example of precision medicine, UAB researchers have used IPF patients own lung tissue to create models to determine the most effective medication for that patient.
A Western-style diet, with more omega-6 fatty acids than the Mediterranean, dysregulates lipid signaling in aged mice and promotes inflammation.
John D. Mountz, M.D., Ph.D., and Jasvinder A. Singh, M.D., have been awarded prestigious rheumatology awards for advances in basic and clinical research.
Antibody VRC01 proves safe for individuals infected with HIV-1 but only modestly controls the virus in participants who stop receiving antiretroviral therapy.

Becker’s Hospital Review ranks the UAB Comprehensive Cancer Center as one of 100 Hospitals and Health Systems with great oncology programs in America. 

A significant new UAB study published in Cancer shows that key socioeconomic factors, not race, affect survival of younger multiple myeloma patients.   

Sowing the Seeds of Health, a longstanding educational program at the UAB Comprehensive Cancer Center, helps to reduce breast and cervical cancer among Latina women. 

Broad telehealth accessibility in Alabama would provide unprecedented access to care in rural areas by eliminating the geographic divide and improving the quality of life for those with chronic and rare diseases. 

The summit will provide an opportunity to learn from people who are experts in their field, some of whom have achieved an enormous amount of success in their own states.
Researchers have found that an interaction between a mutant gene and alpha synuclein in neurons leads to hallmark pathologies seen in Parkinson’s disease, findings that may lead to new mechanisms and targets for neuroprotection.
A quality-control checkpoint in pre-B cells restricts the range of antibodies produced by mature B cells, and manipulation of the checkpoint could make vaccines more potent.
This competitive award recognizes outstanding achievements and contributions to VA research and provides five years of salary support.
Researchers from UAB, Emory and Microsoft demonstrate that HIV has evolved to be pre-adapted to the immune response, worsening clinical outcomes in newly infected patients.
UAB researchers will use a $1.8 million grant to look at single cells for altered expression of the interferon gamma receptor gene.
Results show that JAK/STAT pathway inhibitors may be a new class of therapeutic treatments for patients with Parkinson’s disease. Acting by reducing inflammation, they prevent neurodegeneration in animal models and may be an important new approach to slow progression of the disease.
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