Displaying items by tag: department of biochemistry and molecular genetics

Record $95 million Heersink lead gift to advance strategic growth and biomedical innovation.
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The histone methyltransferase DOT1L — the potential target — is overexpressed in ovarian cancer, and high levels of expression correlate with reduced progression-free and overall survival.
Meier-Gorlin syndrome is a rare genetic developmental disorder that causes dwarfism, small ears, a small brain, missing patella and other skeletal abnormalities.
Everyone was fast this spring: the businesses that contributed to the fund, the scientists and physicians who crafted research proposals, and the senior School of Medicine researchers who chose which proposals got money.
The research is led by an Oregon cancer research institute, in collaboration with two biotech companies and the National Institutes of Health.

The Gilbert Family Foundation’s Gene Therapy Initiative funds researchers at UAB exploring developmental and curative therapies for NF1.

Doctoral student Kwaku Osei came to UAB to learn from top researchers in the dry eye field. His work focuses on a tear film component that could provide a new way to treat a growing vision problem.
This gene silencing by ubiquitinated histone is vital in normal embryo development, and it goes awry in some cancers.
This novel method improves purification of complex proteins by 10- to 500-fold, and it may aid both research and large-scale industrial production.
UAB and UMass researchers have uncovered a new mechanistic understanding of potential treatment for genetic disorders.
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