Displaying items by tag: department of microbiology

Lupus, an autoimmune disease that can attack any part of the body, can be confounding because patients often respond differently to the same treatment, and they vary widely in the severity of their symptoms.
The O’Neal Invests program funds UAB investigators starting new cancer-related projects to initiate key, preliminary work needed to enable competitive R01 applications from the NIH.
Record $95 million Heersink lead gift to advance strategic growth and biomedical innovation.
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The higher infectivity correlates with mutations that increase viral binding to a cell surface glucosaminoglycan, heparan sulfate.

This finding upends the long-held paradigm that priming during lung infections takes place only in the draining lymph nodes, and it will be key to developing more efficient vaccinations and therapies for respiratory challenges.

Six graduate students in the Academic Medical Center of the 21st Century scholarship program will network with medical professionals, train with top research doctors and receive research funding from the UAB School of Medicine. 

MicroCT of infected human lung tissue, along with histology and immunohistochemistry, was used to construct images of TB granulomas, airways and vasculature.

This novel virulence trait, which increases severity of S. pneumoniae superinfection, involves pneumococcal surface protein A, now identified as an adhesin.

A comprehensive health-screening program in rural northern KwaZulu-Natal has found a high burden of undiagnosed or poorly controlled non-communicable diseases.

A single intranasal dose provided sterilizing immunity — no detectable COVID-19 virus — in the lungs of vaccinated mice, in contrast to dense infection in lungs of unvaccinated mice.
Knowledge of the specific flagellins that drive the pathogenic immune response in Crohn’s disease is a step toward a potential preventive treatment.
A bilingual speaker of Japanese, Leanna Miku Crafford volunteered with a nonprofit health care clinic, did research in microbiology and led the Japanese Culture Club. She will graduate May 1 with honors magna cum laude with a Bachelor of Science degree in biology.
This transport system may be widespread across many Gram-positive bacteria that contain proteins in the WXG100 superfamily. Tuberculosis kills 1 million people each year.

Preclinical tests at UAB last year showed potent systemic and mucosal immune responses in mice after a single intranasal dose. The vaccine candidate was developed by Maryland-based Altimmune Inc.

Streptococcus pneumoniae is an opportunistic pathogen that commonly infects young children and the elderly. This atlas will help researchers better understand how to treat these infections.
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