If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
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The RECOVER study was designed in partnership with many of the nation’s top experts in treatment-resistant depression, and approved by Medicare, to provide additional evidence of the benefit of VNS Therapy. If the results confirm previous studies, Medicare and other insurers may start to cover it.

People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them.

To join the RECOVER study, you must be 18 years or
older and:

1. Currently depressed
2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times
3. Have tried at least four types of antidepressant treatments and not found them helpful
4. Have Medicare Insurance
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The UAB Department of Dermatology is seeking people for a clinical study looking into ultraviolet light induced effects on the skin immune responses. This study may provide clues for the prevention of skin cancer. We are seeking 18-35 year old individuals, without a history of skin cancer, who are capable of being sunburned and who are not currently pregnant or planning to become pregnant the next 2 months. Participants may receive up to $500 in compensation. Please contact 205-801-8841 or UVstudy@uabmc.edu for more information.
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We are currently seeking Gulf War Veterans to participate in a brain imaging research study. Healthy Gulf War Veterans and Veterans with chronic health problems are invited to participate. Participation involves 1-2 visits to UAB for 2.5 hours total. Participants undergo MRI brain scan, blood draw, and complete several questionnaires. Participants who complete the study receive $150 compensation. Please email chloej@uab.edu or call 205-434-1502 for more information and to find out if you're eligible.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy African American men having no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting an 81-week research study to evaluate the safety and effectiveness of an investigational drug to treat obesity. In this trial you will receive once weekly injectable semaglutide or placebo along with diet and exercise intervention. To qualify, you must be 18 years old or older, be obese without diabetes. Qualified participants will receive study drug, diet/increased activity counseling, EKG, and Physical Exams. There is no charge for participation. Compensation for time and travel may also be available. For more information, and to see if you might be eligible to join, please contact (205)975-8217 or mcr90@uab.edu.
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Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested

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You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.

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The UAB Department of Dermatology is seeking people for a clinical study looking into ultraviolet light induced effects on the skin immune responses. This study may provide clues for the prevention of skin cancer. We are seeking 18-35 year old individuals, without a history of skin cancer, who are capable of being sunburned and who are not currently pregnant or planning to become pregnant the next 2 months. Participants may receive up to $500 in compensation. Please contact 205-801-8841 or UVstudy@uabmc.edu for more information.
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Are you a caregiver? Do you know someone that is a caregiver? Would you like to earn $20? If so, the Caring for Adults with Difficulties Study (CFAD) needs you! This study examines stressors of caregivers to aging adults, their social support networks, caregiving demands, and personal experiences. To be eligible, you must care for a family member or friend at least 5 hours per week. You must also complete a 45 minute survey online or over the phone. Please contact us by phone (205-975-9452) or email (mjfields@uab.edu). We look forward to your participation asa we are still recruiting participants!
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The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study tests the body’s immune system response to, a protein similar to what is found in HIV. The immune response prepares the body to recognize the same protein in HIV and fight the virus if a person is exposed to HIV in the future. Participants will be compensated over $750 for their efforts.

If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
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If you are 18 or older with a BMI of 35 or greater, a history of calcium oxalate kidney stones, and are desiring to lose weight, you may be eligible to participate in a research study. The goal of this study is to better understand calcium oxalate kidney stone disease and how weight loss might impact urinary oxalate and kidney stone risk. The study requires eating a study diet for 5 days with a one-day long visit both before and after weight loss, participating in a 14-week long weight loss program with the aid of Optifast VLCD® shakes, collecting 24-hr urines, blood samples, and stool samples. Participants will have the opportunity to be compensated up to $920 for participation in the program over the 6 -8-month participation time frame. They will also receive all Optifast products and study meals for free! For more information email kidneystoneresearch@uabmc.edu
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Receive compensation and Free 20-Week Exercise Program.

Eligible enrolled participants will receive:
- Supervised exercise training at no cost
- Blood pressure medication at no cost
- Convenient parking at no cost
- Compensation for time

If you are interested, please call 205-996-3005 and mention The ACES Study or apply here -https://www.uab.edu/medicine/exercise/volunteer-clinical-trials/aces-trial.
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The University of Alabama at Birmingham, Department of Family and Community Medicine, is conducting a 12-month research study to test the effectiveness of a diabetes management intervention. If you have type 2 diabetes, are 18 years or older, and self-identify as Black or African American, you may be eligible to participate. Participants will be compensated up to $300 for completing the study.

For more information, please contact us at: 205-224-2567, or freedom@uabmc.edu, or fill out this pre-screening form and we will get in touch with you: https://redcap.link/freedom
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Help us find out by joining our study at UAB. You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must have a BMI: 30-45 kg/m2), have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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The Targeted Exercise for African Americans with Multiple Sclerosis (TEAAMS) study will examine whether a 16-week home-based, racially-tailored exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black/African Americans with MS who live in rural communities in the Southeastern US. Eligible participants must be 18-64 years old, diagnosed with MS, self-identify as Black or African American, and live in the Southeastern US. Participants will be compensated $90 for completing all study visits. Please contact Edson Flores at enrl@uic.edu or (833) 727-1887 for more information and to see if you qualify.
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Adult ages 40-80 are needed for a study about the anti-inflammatory effects of ensifentrine in patients with COPD. The study involves 7 visits in our clinical research unit, and the collection of urine and blood. Compensation up to $700. For more information, call 205-996-2727 or email Carrie at LungHealth@uabmc.edu.
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Help us find out by joining our study.  The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting an exciting research study, in collaboration with Pennington Biomedical Research Center, to investigate whether intermittent fasting or calorie restriction (i.e., losing weight) can improve health and slow the aging process.   

If you are randomly selected to do calorie restriction, you may lose weight by eating less. If you are randomly selected to do intermittent fasting, you will fast for 16 hours per day and eat dinner by 6 pm about 6 days per week (1 break day per week). We want you to be successful: the study provides intensive coaching and support to help you successfully lose weight or practice intermittent fasting.  

To qualify, you should: 

  • Be 25-45 years old  
  • Have a BMI between 22-30 Calculate your BMI here  
  • Be healthy 
  • Not currently taking any medications or supplements for chronic conditions 
  • Not smoke, vape, or use tobacco products currently or within the last 6 months 
  • Not currently participate in a regular program of heavy physical activity (e.g., jogging, running, or riding fast on a bicycle for 30 minutes or more per day)
The study involves collecting a medical history, body fat and bone scans, blood draws, urine collection, questionnaires, and other simple tests.  Participation in the study will last approximately 7 months.  Compensation of up to $850 is offered for the completion of this study. If you are interested in participating and think you may be eligible, please click the button below to screen online, call 205-934-1457, or email dial@uab.edu.  

www.pbrc.edu\dialhealthuab 
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Feel like you're missing out? If you are being treated for major depressive disorder (MDD) but still feel a lack or loss of interest in usually pleasurable activities, the TERPSIS Study, a clinical research study on an investigational medication for MDD, be of interest to you. The TERPSIS Study is researching a potential MDD therapy to improve symptoms of depression, and you may be eligible to participate. This study is now enrolling adults diagnosed with MDD Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no costs. Participants in the TERPSIS Study must: -Be 18 to 65 years of age -Have a clinical diagnosis of MDD -Are currently taking or have recently taken antidepressant medication(s) -Still feel a lack of interest in usually pleasurable activities -Fulfill other eligibility criteria For more information, please email kristinepike@uabmc.edu or call 205-975-8542.
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A clinical research study is now enrolling eligible adults. The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an investigational medication when it is used alone in people with TRD. You may be eligible to participate if you: • Are 18 years of age or older • Have been diagnosed with TRD • Have not adequately responded to at least 2 different antidepressant treatments If you are interested, additional eligibility criteria will be assessed by the study doctor or staff. The commitment for the study is about 24 weeks. Qualified patients may receive investigational study medication and some study-required medical care at no cost. For more information about this study, you may visit www.clinicaltrials.gov and search “54135419TRD4005” or contact Kristine at 205-975-8542 or kristinepike@uabmc.edu.

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You could be eligible to participate if you are 18 or older and a premenopausal female. Also, If you have been diagnosed with endometriosis, and are experiencing pain associated with endometriosis. There is no cost for your participation. For more information, contact our research team at 205-934-1322 or email slangan@uabmc.edu. Compensation is available for those who qualify
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You may be eligible to participate in this important study if you are premenopausal female age 18-49, if you have been diagnosed with endometriosis, and are experiencing moderate to severe pain associated with your endometriosis. There is no cost for your participation. For more information, contact our research team at 205-934-1322. Compensation is available for those who qualify. https://endometriosis-study.com/
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Help researchers at UAB have a better understanding of how the body changes with physical activity. We’re looking for men and women who are 18 years of age and older who do not exercise regularly to participate in our MoTrPAC research study. You can receive up to $1500 compensation for your time. If you would like to have the opportunity to participate in fitness testing and have study-related exams at UAB Center for Exercise Medicine, please email motrpac@uab.edu or apply here.
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Participants between the ages 65-84 needed for a research study on balance. This study is being done to determine how balance (or your ability stay upright while initiating gait from standing position) by older adults is affected as you step over an obstacle placed at different distances forward and stepping sideways. If you qualify, we anticipate that your participation in the study session will be no more than three hours. You will be compensated for your time. Please e-mail Dr. Christopher Hurt, cphurt@uab.edu or contact him at 934-8517 if you are interested.
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