With funding from UAB’s urgent COVID-19 research grants, researchers are testing penehyclidine to halt the acute respiratory distress syndrome seen in seriously ill patients by defending crucial cell barriers.

Benjamin Larimer, Ph.D., has received a five-year, $1.5-million New Innovator Award grant to develop a PET imaging test that identifies patients most likely to benefit from immunotherapy.

Using extensive testing, diagnosis and clinical data from across the Deep South, this project will be the first to analyze multiple dimensions of inequality to clarify contributions to COVID-19 disparities.

The immune system’s first responders are implicated in acute respiratory distress syndrome, which greatly increases mortality in patients with COVID-19. With pilot funding from UAB’s urgent COVID-19 research initiative, investigators are exploring a potentially powerful new form of treatment.

Moon Nahm, M.D., has identified the crucial antibodies for pneumococcal vaccines and helped lower prices from $100 per dose to $2. With pilot funding from UAB’s urgent COVID-19 research initiative, Nahm is adapting his proven techniques to SARS-CoV-2.

Alabamians have early access to potentially life-saving vaccines and treatments for COVID-19 through UAB. Why? The same reasons that clinical trials activity at UAB has more than doubled in the past five years. Here's how it happened.

A bioluminescent one-two punch targets mitochondria in cancer cells and evades the blood-brain barrier for a potential new treatment for neuroendocrine cancers, triple-negative breast cancer and brain cancers.

In a new trial funded through UAB’s urgent COVID-19 research program, investigators are comparing the widely available steroid methylprednisolone with dexamethasone, which lowered risk of dying by one-third in a U.K. trial this summer.

With a nearly $3 million grant from the NIH, researchers are studying interactions among sleep, nicotine and race.

Project LEAP will make novel use of integrated patient navigation and student champions to help high-risk young residents.

This summer’s COVID-19 Data Science Hackathon spurred many creative applications and several ongoing projects, including an automated genomic epidemiology pipeline and a machine-learning based viral transmission simulator.

Interdisciplinary center is focused on cutting-edge research that can be developed into better treatments — and helping junior faculty develop their own research programs.

A $2.9 million study aims to lower the risk of pregnant women becoming infected with cytomegalovirus, a virus that can lead to long-term health problems for babies.

Women who had total body irradiation to prepare for blood or marrow transplantation before age 30 had a 4.5-fold increase in their risk of developing breast cancer later in life.

Precision mapping using drones, light aircraft and lasers enables Rouzbeh Nazari, Ph.D., to pinpoint homes at highest risk in hurricanes and other disasters.

A $2.9 million, NIH-funded trial aimed at Black women with high stress will examine whether culturally relevant stress-management strategies can improve weight-loss outcomes.

Department creates environment for entrepreneurial activity that fuels advances in artificial intelligence, cancer prediction and patient safety.

In a new paper, Keshav Singh, Ph.D., outlines the case for the “powerhouse of the cell” as a hideout and unwitting ally for SARS-CoV-2.

Researchers from UAB’s Precision Medicine Institute have used AI to identify hundreds of potential treatments, which are now being tested through the COVID-19 research fund that the institute helped launch.

New microbiology faculty member Nicholas Lennemann is transforming the fluorescent virus assay he developed into a new tool against coronavirus in work supported through UAB’s urgent COVID-19 research fund.

Bioreactors built to offer new insights on lung cancer are being adapted to study coronavirus infection and test new treatments in this project supported through UAB’s urgent COVID-19 research fund.

Virologist Kevin Harrod, Ph.D., is the institution’s resident expert on SARS viruses. His lab is handling biological validation for innovative drug-repurposing studies supported by the School of Medicine’s Urgent COVID-19 research fund.

Microbiologists Troy Randall and Frances Lund are building key proteins from several coronaviruses to study antibody cross-reactivity and other crucial questions in this project supported through UAB’s urgent COVID-19 research fund.

In this project supported through UAB’s urgent COVID-19 research fund, Professor Randall Davis aims to identify antibodies that block SARS-CoV-2 from entering human cells — information that could guide convalescent plasma therapy and more.

Protecting workers’ vision has become more challenging as a diverse workforce stretches the definition of a “typical” face. UAB researchers are going 3D to keep employees safe.

In this project supported through UAB’s urgent COVID-19 research fund, Assistant Professor Benjamin Larimer, Ph.D., adapts his lab’s work on phage display — normally used to identify new cancer treatments — to overcome limitations of antibody and vaccine testing.

Researchers in the School of Public Health illustrate how tweets labeling the novel coronavirus as the “Chinese virus” exploded across the United States.

Trial to rapidly identify and treat the immune overreaction that may be behind some cases of severe COVID-19 is made possible through UAB Medicine’s Urgent COVID-19 Clinical Research and Laboratory Research Fund.

Educating new primary care physicians about effective treatments for opioid use disorder in partnership with Cahaba Medical Care.

Just in time to tackle COVID-19, the Informatics Institute launches a bigger, more capable version of its team-science data platform.

Lab-grown human heart tissue could mean better drug tests, faster transplants and more accurate models of disease. To get there, Palaniappan Sethu, Ph.D., is stretching ingenuity.

UAB algorithm offers doctors a step-by-step guide to connect patients with HIV to best smoking-cessation options.

Ariann Nassel in the Lister Hill Center for Health Policy works with UAB researchers to reveal patterns in patient care, neighborhood features, dental practices and more.

New UAB research is combining mathematical modeling and advanced imaging to find the right mix of therapy for patients with a common subtype of breast cancer.

Are there differences in the way that minority groups and people with low socioeconomic status experience chronic low back pain? Learn more about an ongoing study in this new series that looks behind the scenes of UAB’s latest grants and contracts.

Learn how UAB researchers are taking on the most feared complication of the new generation of blood-thinning drugs. 

An innovative grant aims to speed up antiretroviral therapy initiation for patients in the Deep South newly diagnosed with HIV.

UAB-led study finds that genetic variations associated with cognitive decline after BMT identify high-risk patients more accurately than current methods.

Go behind the scenes of UAB’s latest grants and contracts in this new series to discover a fresh approach to treat an autoimmune disease and its mysterious double-negative B cells.

Go behind the scenes of our latest grants and contracts in this new series — including a grant that is taking UAB investigators into the heart of the dark web of opioid trafficking.