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Important updates to UAB's COVID-19 health and safety policies and our mission to help fight COVID-19
Research
  • Studying an alternative steroid treatment to calm cytokine storms in COVID-19
    Studying an alternative steroid treatment to calm cytokine storms in COVID-19
  • How UAB became a national leader in clinical trials
    How UAB became a national leader in clinical trials
  • This glow-in-the-dark Trojan horse makes cancer cells build their own self-destruct switch
    This glow-in-the-dark Trojan horse makes cancer cells build their own self-destruct switch

Study testing drug to protect lung cells from ARDS in COVID-19

Study testing drug to protect lung cells from ARDS in COVID-19

‘High-risk, high-reward’ NIH grant expands researcher’s work predicting cancer immunotherapy success

‘High-risk, high-reward’ NIH grant expands researcher’s work predicting cancer immunotherapy success

Your ZIP code is a risk factor for COVID-19: Study will identify where testing, therapies are needed most

Your ZIP code is a risk factor for COVID-19: Study will identify where testing, therapies are needed most

Could NET-wielding neutrophils be driving respiratory distress and death in COVID-19 patients?

Could NET-wielding neutrophils be driving respiratory distress and death in COVID-19 patients?

Better tests, cheaper vaccines: Antibody expert turns to COVID-19

Better tests, cheaper vaccines: Antibody expert turns to COVID-19

How UAB became a national leader in clinical trials

How UAB became a national leader in clinical trials

This glow-in-the-dark Trojan horse makes cancer cells build their own self-destruct switch

This glow-in-the-dark Trojan horse makes cancer cells build their own self-destruct switch

Studying an alternative steroid treatment to calm cytokine storms in COVID-19

Studying an alternative steroid treatment to calm cytokine storms in COVID-19

More...

Chronotypes and cigarettes: New study explores strategies to help ethnic minorities get better rest and quit smoking

Chronotypes and cigarettes: New study explores strategies to help ethnic minorities get better rest and quit smoking

Project aims to address HIV and substance use in Jefferson County youth

Project aims to address HIV and substance use in Jefferson County youth

Data wizards join fight against COVID-19 in UAB hackathon

Data wizards join fight against COVID-19 in UAB hackathon

Study testing behavioral intervention to prevent CMV, major cause of hearing loss in young children

Study testing behavioral intervention to prevent CMV, major cause of hearing loss in young children
  • Study testing drug to protect lung cells from ARDS in COVID-19 Discoveries & Innovations
    Study testing drug to protect lung cells from ARDS in COVID-19

    With funding from UAB’s urgent COVID-19 research grants, researchers are testing penehyclidine to halt the acute respiratory distress syndrome seen in seriously ill patients by defending crucial cell barriers.

    posted a while back 1059 views
  • ‘High-risk, high-reward’ NIH grant expands researcher’s work predicting cancer immunotherapy success Grants Awarded
    ‘High-risk, high-reward’ NIH grant expands researcher’s work predicting cancer immunotherapy success

    Benjamin Larimer, Ph.D., has received a five-year, $1.5-million New Innovator Award grant to develop a PET imaging test that identifies patients most likely to benefit from immunotherapy.

    posted a while back 568 views
  • Your ZIP code is a risk factor for COVID-19: Study will identify where testing, therapies are needed most Discoveries & Innovations
    Your ZIP code is a risk factor for COVID-19: Study will identify where testing, therapies are needed most

    Using extensive testing, diagnosis and clinical data from across the Deep South, this project will be the first to analyze multiple dimensions of inequality to clarify contributions to COVID-19 disparities.

    posted a while back 3240 views
  • Could NET-wielding neutrophils be driving respiratory distress and death in COVID-19 patients? Discoveries & Innovations
    Could NET-wielding neutrophils be driving respiratory distress and death in COVID-19 patients?

    The immune system’s first responders are implicated in acute respiratory distress syndrome, which greatly increases mortality in patients with COVID-19. With pilot funding from UAB’s urgent COVID-19 research initiative, investigators are exploring a potentially powerful new form of treatment.

    posted a while back 1813 views
  • Better tests, cheaper vaccines: Antibody expert turns to COVID-19 Discoveries & Innovations
    Better tests, cheaper vaccines: Antibody expert turns to COVID-19

    Moon Nahm, M.D., has identified the crucial antibodies for pneumococcal vaccines and helped lower prices from $100 per dose to $2. With pilot funding from UAB’s urgent COVID-19 research initiative, Nahm is adapting his proven techniques to SARS-CoV-2.

    posted a while back 1184 views
  • How UAB became a national leader in clinical trials Discoveries & Innovations
    How UAB became a national leader in clinical trials

    Alabamians have early access to potentially life-saving vaccines and treatments for COVID-19 through UAB. Why? The same reasons that clinical trials activity at UAB has more than doubled in the past five years. Here's how it happened.

    posted a while back 4153 views
  • This glow-in-the-dark Trojan horse makes cancer cells build their own self-destruct switch Discoveries & Innovations
    This glow-in-the-dark Trojan horse makes cancer cells build their own self-destruct switch

    A bioluminescent one-two punch targets mitochondria in cancer cells and evades the blood-brain barrier for a potential new treatment for neuroendocrine cancers, triple-negative breast cancer and brain cancers.

    posted a while back 1500 views
  • Studying an alternative steroid treatment to calm cytokine storms in COVID-19 Discoveries & Innovations
    Studying an alternative steroid treatment to calm cytokine storms in COVID-19

    In a new trial funded through UAB’s urgent COVID-19 research program, investigators are comparing the widely available steroid methylprednisolone with dexamethasone, which lowered risk of dying by one-third in a U.K. trial this summer.

    posted a while back 1951 views
  • Chronotypes and cigarettes: New study explores strategies to help ethnic minorities get better rest and quit smoking Discoveries & Innovations
    Chronotypes and cigarettes: New study explores strategies to help ethnic minorities get better rest and quit smoking

    With a nearly $3 million grant from the NIH, researchers are studying interactions among sleep, nicotine and race.

    posted a while back 1708 views
  • Project aims to address HIV and substance use in Jefferson County youth Discoveries & Innovations
    Project aims to address HIV and substance use in Jefferson County youth

    Project LEAP will make novel use of integrated patient navigation and student champions to help high-risk young residents.

    posted a while back 1413 views
  • Data wizards join fight against COVID-19 in UAB hackathon Discoveries & Innovations
    Data wizards join fight against COVID-19 in UAB hackathon

    This summer’s COVID-19 Data Science Hackathon spurred many creative applications and several ongoing projects, including an automated genomic epidemiology pipeline and a machine-learning based viral transmission simulator.

    posted a while back 1764 views
  • New addiction and pain prevention center aims to rally researchers and community Discoveries & Innovations
    New addiction and pain prevention center aims to rally researchers and community

    Interdisciplinary center is focused on cutting-edge research that can be developed into better treatments — and helping junior faculty develop their own research programs.

    posted a while back 1535 views
  • Study testing behavioral intervention to prevent CMV, major cause of hearing loss in young children Discoveries & Innovations
    Study testing behavioral intervention to prevent CMV, major cause of hearing loss in young children

    A $2.9 million study aims to lower the risk of pregnant women becoming infected with cytomegalovirus, a virus that can lead to long-term health problems for babies.

    posted a while back 952 views
  • BMT survivor study finds significant breast cancer risk in young women who received total body irradiation Discoveries & Innovations
    BMT survivor study finds significant breast cancer risk in young women who received total body irradiation

    Women who had total body irradiation to prepare for blood or marrow transplantation before age 30 had a 4.5-fold increase in their risk of developing breast cancer later in life.

    posted a while back 1163 views
  • Which beach will bust? A high-tech flood forecaster predicts water’s next move like no one else Discoveries & Innovations
    Which beach will bust? A high-tech flood forecaster predicts water’s next move like no one else

    Precision mapping using drones, light aircraft and lasers enables Rouzbeh Nazari, Ph.D., to pinpoint homes at highest risk in hurricanes and other disasters.

    posted a while back 2171 views
  • New weight-loss study focusing on stress — the diet killer Discoveries & Innovations
    New weight-loss study focusing on stress — the diet killer

    A $2.9 million, NIH-funded trial aimed at Black women with high stress will examine whether culturally relevant stress-management strategies can improve weight-loss outcomes.

    posted a while back 1671 views
  • Radiology is investing in innovation and spinning off startups. What’s the secret? Discoveries & Innovations
    Radiology is investing in innovation and spinning off startups. What’s the secret?

    Department creates environment for entrepreneurial activity that fuels advances in artificial intelligence, cancer prediction and patient safety.

    posted a while back 1668 views
  • Hijacked mitochondria could induce COVID-19, study says Discoveries & Innovations
    Hijacked mitochondria could induce COVID-19, study says

    In a new paper, Keshav Singh, Ph.D., outlines the case for the “powerhouse of the cell” as a hideout and unwitting ally for SARS-CoV-2.

    posted a while back 11002 views
  • Machine-learning tools find targets old drugs can exploit against COVID-19 Discoveries & Innovations
    Machine-learning tools find targets old drugs can exploit against COVID-19

    Researchers from UAB’s Precision Medicine Institute have used AI to identify hundreds of potential treatments, which are now being tested through the COVID-19 research fund that the institute helped launch.

    posted a while back 1813 views
  • Glow-in-the-dark coronavirus testing is first project of new hire Discoveries & Innovations
    Glow-in-the-dark coronavirus testing is first project of new hire

    New microbiology faculty member Nicholas Lennemann is transforming the fluorescent virus assay he developed into a new tool against coronavirus in work supported through UAB’s urgent COVID-19 research fund.

    posted a while back 4480 views
  • Researchers model COVID-19 infection in 3D human lung tissue Discoveries & Innovations
    Researchers model COVID-19 infection in 3D human lung tissue

    Bioreactors built to offer new insights on lung cancer are being adapted to study coronavirus infection and test new treatments in this project supported through UAB’s urgent COVID-19 research fund.

    posted a while back 3918 views
  • Tackling his third pandemic, UAB researcher gets up close with coronaviruses in order to kill them Discoveries & Innovations
    Tackling his third pandemic, UAB researcher gets up close with coronaviruses in order to kill them

    Virologist Kevin Harrod, Ph.D., is the institution’s resident expert on SARS viruses. His lab is handling biological validation for innovative drug-repurposing studies supported by the School of Medicine’s Urgent COVID-19 research fund.

    posted a while back 2725 views
  • Researchers are creating a coronavirus showdown to settle pressing antibody problems Discoveries & Innovations
    Researchers are creating a coronavirus showdown to settle pressing antibody problems

    Microbiologists Troy Randall and Frances Lund are building key proteins from several coronaviruses to study antibody cross-reactivity and other crucial questions in this project supported through UAB’s urgent COVID-19 research fund.

    posted a while back 2217 views
  • Where are the good antibodies against COVID-19? UAB project aims to find out Discoveries & Innovations
    Where are the good antibodies against COVID-19? UAB project aims to find out

    In this project supported through UAB’s urgent COVID-19 research fund, Professor Randall Davis aims to identify antibodies that block SARS-CoV-2 from entering human cells — information that could guide convalescent plasma therapy and more.

    posted a while back 2120 views
  • Discoveries on deck: Searching for a better fit for safety eyewear Discoveries & Innovations
    Discoveries on deck: Searching for a better fit for safety eyewear

    Protecting workers’ vision has become more challenging as a diverse workforce stretches the definition of a “typical” face. UAB researchers are going 3D to keep employees safe.

    posted a while back 1507 views
  • Helpful viruses may unlock the secrets of coronavirus antibodies Discoveries & Innovations
    Helpful viruses may unlock the secrets of coronavirus antibodies

    In this project supported through UAB’s urgent COVID-19 research fund, Assistant Professor Benjamin Larimer, Ph.D., adapts his lab’s work on phage display — normally used to identify new cancer treatments — to overcome limitations of antibody and vaccine testing.

    posted a while back 3009 views
  • #Chinavirus study explores spread of COVID-19 related stigma on Twitter Discoveries & Innovations
    #Chinavirus study explores spread of COVID-19 related stigma on Twitter

    Researchers in the School of Public Health illustrate how tweets labeling the novel coronavirus as the “Chinese virus” exploded across the United States.

    posted a while back 2756 views
  • Cytokine storm treatment for coronavirus patients is focus of first-in-US study Discoveries & Innovations
    Cytokine storm treatment for coronavirus patients is focus of first-in-US study

    Trial to rapidly identify and treat the immune overreaction that may be behind some cases of severe COVID-19 is made possible through UAB Medicine’s Urgent COVID-19 Clinical Research and Laboratory Research Fund.

    posted a while back 7711 views
  • Discoveries on deck: Strategic planning against opioid disorders Discoveries & Innovations
    Discoveries on deck: Strategic planning against opioid disorders

    Educating new primary care physicians about effective treatments for opioid use disorder in partnership with Cahaba Medical Care.

    posted a while back 1641 views
  • Is U-BRITE 2.0 right for you? Discoveries & Innovations
    Is U-BRITE 2.0 right for you?

    Just in time to tackle COVID-19, the Informatics Institute launches a bigger, more capable version of its team-science data platform.

    posted a while back 2077 views
  • Growing heart cells in a lab — one beat at a time Discoveries & Innovations
    Growing heart cells in a lab — one beat at a time

    Lab-grown human heart tissue could mean better drug tests, faster transplants and more accurate models of disease. To get there, Palaniappan Sethu, Ph.D., is stretching ingenuity.

    posted a while back 2618 views
  • Discoveries on deck: Helping vulnerable patients quit smoking Discoveries & Innovations
    Discoveries on deck: Helping vulnerable patients quit smoking

    UAB algorithm offers doctors a step-by-step guide to connect patients with HIV to best smoking-cessation options.

    posted a while back 1644 views
  • As coronavirus dashboards enthrall millions, a mapping guru reflects on the power of visualization Discoveries & Innovations
    As coronavirus dashboards enthrall millions, a mapping guru reflects on the power of visualization

    Ariann Nassel in the Lister Hill Center for Health Policy works with UAB researchers to reveal patterns in patient care, neighborhood features, dental practices and more.

    posted a while back 2700 views
  • Discoveries on deck: Equations + images against HER2+ breast cancer Discoveries & Innovations
    Discoveries on deck: Equations + images against HER2+ breast cancer

    New UAB research is combining mathematical modeling and advanced imaging to find the right mix of therapy for patients with a common subtype of breast cancer.

    posted a while back 1875 views
  • Discoveries on deck: Back pain, race and money Discoveries & Innovations
    Discoveries on deck: Back pain, race and money

    Are there differences in the way that minority groups and people with low socioeconomic status experience chronic low back pain? Learn more about an ongoing study in this new series that looks behind the scenes of UAB’s latest grants and contracts.

    posted a while back 2063 views
  • Discoveries on deck: Predicting uncontrolled bleeding Discoveries & Innovations
    Discoveries on deck: Predicting uncontrolled bleeding

    Learn how UAB researchers are taking on the most feared complication of the new generation of blood-thinning drugs. 

    posted a while back 1793 views
  • Discoveries on deck: Accelerating HIV suppression in the Deep South Discoveries & Innovations
    Discoveries on deck: Accelerating HIV suppression in the Deep South

    An innovative grant aims to speed up antiretroviral therapy initiation for patients in the Deep South newly diagnosed with HIV.

    posted a while back 2283 views
  • Genetics may predict cancer patients at highest risk of ‘chemo brain’ after blood or marrow transplant Discoveries & Innovations
    Genetics may predict cancer patients at highest risk of ‘chemo brain’ after blood or marrow transplant

    UAB-led study finds that genetic variations associated with cognitive decline after BMT identify high-risk patients more accurately than current methods.

    posted a while back 2523 views
  • Discoveries on deck: Exploring a new strategy against lupus Discoveries & Innovations
    Discoveries on deck: Exploring a new strategy against lupus

    Go behind the scenes of UAB’s latest grants and contracts in this new series to discover a fresh approach to treat an autoimmune disease and its mysterious double-negative B cells.

    posted a while back 2608 views
  • Discoveries on deck: Blocking fentanyl at the source Discoveries & Innovations
    Discoveries on deck: Blocking fentanyl at the source

    Go behind the scenes of our latest grants and contracts in this new series — including a grant that is taking UAB investigators into the heart of the dark web of opioid trafficking.  

    posted a while back 3646 views
 

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Clinical Trials

  • Men ages 39-65 needed for research study involving fibromyalgia and/or chronic fatigue syndrome
    Tags: men fibromyalgia chronic fatigue syndrome
  • Adolescents and young adults ages 16-30 with autism and with attention-deficit/hyperactivity disorder needed for driving study
    Tags: adolescents driving autism ADHD
  • Volunteers needed for exercise and blood pressure study
    Tags: blood pressure men women exercise heart disease
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