COVID-19 bacteremic co-infection is a major risk factor for mortality, ICU admission, and mechanical ventilation-featuring Drs. Nathaniel Erdmann, M.D., Ph.D., Amit Gaggar, M.D., and Matthew Might, Ph.D.

Border-associated macrophages mediate the neuroinflammatory response in an alpha-synuclein model of Parkinson's disease-featuring Dr. Ashley Harms, Ph.D.

NAD(H) homeostasis underlies host protection mediated by glycolytic myeloid cells in tuberculosis-featuring Dr. Adrie Steyn, Ph.D.

A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans-featuring Drs. Frances Lund and Anoma Nellore

A high-resolution 3D atlas of the spectrum of tuberculous and COVID-19 lung lesions-featuring Adrie Steyn, Ph.D.

Selective suppression of melanoma lacking IFN-γ pathway by JAK inhibition depends on T cells and host TNF signaling-featuring Lewis Zhichang Shi, M.D., Ph.D.

A nonredundant role for T cell-derived interleukin 22 in antibacterial defense of colonic crypts-featuring Casey T. Weaver, M.D.

Intrinsic IL-2 production by effector CD8 T cells affects IL-2 signaling and promotes fate decisions, stemness, and protection-featuring Allan Zajac, Ph.D.

Development of an arteriolar niche and self-renewal of breast cancer stem cells by lysophosphatidic acid/protein kinase D signaling-featuring Bin Ren, M.D., Ph.D.

ICOS ligand and IL-10 synergize to promote host–microbiota mutualism-featuring Craig Maynard, Ph.D.

Pore-forming Esx proteins mediate toxin secretion by Mycobacterium tuberculosis-featuring Michael Niederweis, Ph.D.

E-cadherin is regulated by GATA-2 and marks the early commitment of mouse hematopoietic progenitors to the basophil and mast cell fates-featuring Robert Welner, Ph.D.

PAGER-CoV: a comprehensive collection of pathways, annotated gene-lists, and gene signatures for coronavirus disease studies-featuring Jake Chen, Ph.D.

Identification of an anti-diabetic, orally available small molecule that regulates TXNIP expression and glucagon action-featuring Anath Shalev, M.D.

Sustained cellular immune dysregulation in individuals recovering from SARS-CoV-2 infection-featuring Nathaniel Erdmann, M.D., Ph.D.

Mitochondrial oxidative phosphorylation regulates the fate decision between pathogenic Th17 and regulatory T Cells-featuring Laurie Harrington, Ph.D.

Defining genetic variation in widely used congenic and backcrossed mouse models reveals varied regulation of genes important for immune responses-featuring Amy Weinmann, Ph.D.

Impaired tumor-necrosis-factor-alpha-driven dendritic cell activation limits lipopolysaccharide-induced protection from allergic inflammation in infants-featuring Beatriz León, Ph.D.

The establishment of resident memory B cells in the lung requires local antigen encounter-featuring Troy Randall, Ph.D.

Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells-featuring Casey Weaver, M.D.

NAD+ depletion triggers programmed cell death to kill macrophages infected with Mycobacterium tuberculosis-featuring Michael Niederweis, Ph.D.

Verapamil is effective as type 1 diabetes therapy-featuring Anath Shalev, M.D.

Immune cells that create and sustain chronic inflammatory bowel disease identified-featuring Laurie Harrington, Ph.D.