UAB is a lead site in new NCI national clinical trials network

cancer center ext 2013-9aUAB’s Comprehensive Cancer Center was selected by the National Cancer Institute to be part of the nation’s primary infrastructure to conduct clinical trials for cancer treatment and advanced imaging — especially large, definitive, multi-institutional trials evaluating new therapies and clinical approaches for adult and children.

As one of 30 lead academic sites in the National Clinical Trials Network chosen through competitive peer-review, UAB will receive a five-year, $2.5 million grant that will enable it to expand its research and patient-care options. More than 180 cancer-related clinical trials exploring a wide array of therapies, diagnostics and preventive options are underway at UAB now.

“With this grant, we now are able to open our clinical trials across a nationwide network,” said Edward Partridge, M.D., director of the UAB Comprehensive Cancer Center. “We are thrilled to have the opportunity to provide patient access to treatment options that they might not otherwise have.”

NCI reports the new network is part of a changing landscaping that will facilitate the rapid initiation and completion of clinical trials by improving the data-management infrastructure, developing a standardized process for prioritizing new studies, consolidating component research groups to improve efficiency and ensuring a unified system of research subject protection at more than 3,000 clinical trial sites.

Several UAB faculty from multiple departments helped bring the grant to fruition, including principal investigator Professor Ronald Alvarez, M.D., director of the Division of Gynecologic Oncology.

“This multi-faceted approach maintains the Cancer Center’s connections with the national cancer research community while fostering the development of translational research linked to UAB’s scientific resources,” Alvarez said.

“This project reflects the collaborative nature of the UAB Cancer Center, involving hematology and oncology, radiation oncology, gynecologic oncology and radiology, all working together for the greater good, and on an even broader level than previously possible,” Alvarez said.

Co-principal investigators include Associate Professor Jennifer De Los Santos, M.D.; Professor Warner Huh, M.D.; Professor Harry Erba, M.D.; Professor Desiree Morgan, M.D.; Professor Carla Falkson, M.D.; and Professor Andres Forero, M.D.

Research & Scholarship

  • UAB is NIH center of excellence for biology of aging research
    NIH's National Institute on Aging has designated UAB a Nathan Shock Center, one of six nationwide expected to provide leadership in basic research into the biology of aging. UAB will receive a five-year, $2.5 million award to establish the center and pursue its research on the relationship between energetics and aging.
    posted 19 days ago 326 views
  • When computers learn to understand doctors' notes, the world will be a better place
    By training computers to pick out timing clues in medical records, UAB machine learning expert Steven Bethard, Ph.D., aims to help individual physicians visualize patient histories, and researchers recruit for clinical trials.
    posted a while back 489 views
  • Graduate training to improve special education services gets a boost
    A $1.25 million grant from the U.S. Department of Education will fund scholarships, provide research opportunities and support collaboration between UAB's schools of Education and Health Professions to improve education services for young children with disabilities. Professor Jennifer Kilgo, Ed.D., who directs Project TransTeam, expects to train 70 scholars in five years.
    posted a while back 614 views
  • Men and women process chronic pain differently
    Robert Sorge, Ph.D., assistant professor of psychology, is lead author of a paper published in Nature Neuroscience online that disputes the assumption that a common pain circuit exists in both sexes. New research shows males and females may use very different biological systems to process pain; the key difference appears to be in the immune system and under control of testosterone.
    posted a while back 605 views
  • Will your self-driving car be programmed to kill you?
    The computer brains inside autonomous vehicles will be fast enough to make life-or-death decisions. But should they? A member of UAB’s national championship-winning Bioethics Bowl team — and the team’s coach, a renowned bioethicist — weigh in on a thorny problem of the dawning robot age.
    posted a while back 858 views
  • “Extra costs of extra weight for older adults”

    UAB research, clinical services featured in PBS story that examines the high and rising costs of health care for obese adults as they age.
    posted a while back 1150 views
  • Smartphones are learning new tricks
    sensomatic main imageYou may think your phone can already do everything, but UAB cybersecurity researchers are adapting accelerometers, GPS chips, gyroscopes and other sensors to make phones that can read your mood, eliminate passwords, protect your bank account and more.
    posted a while back 1074 views
  • Renowned expert named inaugural director of UAB Informatics Institute
    James J. Cimino, M.D., will lead UAB's new Informatics Institute, which was established in June 2014. Cimino, who previously was the chief of the Laboratory for Informatics Development at the NIH Clinical Center and a senior scientist at the National Library of Medicine, is a national leader in the field of biomedical informatics and co-editor of the most influential textbook on the subject.
    posted a while back 1299 views
  • Research enters data-driven era
    During the past few years, technological innovations have opened up an entirely new way to approach scientific questions. Data-driven research starts with massive information sets — the genomic profiles of thousands of patients, for example, or millions of spam emails — and then searches for emerging patterns in that data. In the latest issue of the U.S. Chamber of Commerce’s "Business Horizon Quarterly", UAB President Ray Watts, M.D., explains the way data-driven research at UAB is being applied to find novel treatments for disease, create new products and businesses and train the next generation of innovation-savvy students.
    posted a while back 1425 views