Displaying items by tag: chronic illness

Systemic lupus erythematosus (SLE) is a debilitating autoimmune disease. Our goal is to build a first-of-its-kind database together with patients like you. Sample and information you provide can help us better understand lupus and design more impactful research. There is no cost to join and many of the tests and samples to be collected can be conducted as a part of the routine care you would regular be receiving from your healthcare provider. The purpose of this registry and biorepository study is to collect information from participants with lupus to help researchers learn more about the disease and to help design other studies in the future.
Published in Clinical Trials

About the Clinical Trial:

The purpose of this NIH funded trial is to examine the effects of three different diabetes treatments to determine if they improve night-time blood sugars.

This Trial Involves:

  • A screening visit that includes a blood draw, urine test and physical exam
  • Treatment with Metformin, Insulin Glargine (long-acting insulin) or the experimental drug Dorzagliatin which is FDA-approved for research, for up to 8 weeks
  • 2-4 inpatient visits/ including two overnight stays at the Clinical Research Unit at 15th floor of Jefferson Tower.

All visits to be completed within a three-month period. Study-related tests and procedures are provided free of charge. Participants will be compensated up to $2,500 for study completion. All Participants must be Diagnosed with type 2 DM and Not on any type of insulin therapy.

Please contact Kathryn Hollifield-Laumer at khollifield@uabmc.edu or co-investigators Chanel Mason at 205-934-1921 or cnmason@uabmc.edu, or Alaaeldin Hodhod at ahodhod@uabmc.edu.

Published in Clinical Trials
There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression.

To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue.

If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you.

For more information please contact 205-996-1198 or spremani@uab.edu
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Are you experiencing pain due to endometriosis? Please consider joining a research study looking at a potential new medication to help women experiencing moderate to severe endometriosis-related pain. Study medication provided at no cost. Participants receive compensation for each visit completed. For more information please call 205-934-1322 or email slangan@uabmc.edu.
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UAB is looking for participants for a study investigating the effects of a new study medication on symptoms of fibromyalgia. We are looking for women aged 25-65 who are diagnosed with fibromyalgia OR are experiencing chronic widespread bodily pain. Participants will come to UAB for 7 study visits over a 3-month period. Participants will be compensated for completing all study visits.

Please call 205-996-1198 if interested.
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The purpose of this study is to evaluate if COPD is caused by exposure to heavy metals. This study will include a medical history review, a brief physical examination, spirometry, exhaled breath condensate, urine sample, blood collection, and a bronchoscopy/bronchoalveolar lavage procedure. Those who qualify will receive compensation for their time. Participation is voluntary. Participants in the study must: be 18 to 65 years of age; live in defined zip codes, 35207, 35217, 35214; and fulfill other eligibility criteria to include a medical and medication history for evaluation. For more information, please call (205) 996-1769 or email uabsuperfund@uabmc.edu.
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Are you a HIV negative, generally healthy adult between the ages of 18-55?
The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study is to evaluate the safety and immunogenicity of synthetic DNAs encoding in adults without HIV. This trial is in search of healthy HIV negative adults between the ages of 18-55. Procedures will include blood draws and injections of study vaccine, as well as the collection of white blood cells. White blood cells will be collected by a procedure called leukapheresis. Participants will be compensated for their efforts in this study.

If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
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We are currently seeking Gulf War Veterans to participate in a brain imaging research study. Healthy Gulf War Veterans and Veterans with chronic health problems are invited to participate. Participation involves 1-2 visits to UAB for 2.5 hours total. Participants undergo MRI brain scan, blood draw, and complete several questionnaires. Participants who complete the study receive $150 compensation. Please email chloej@uab.edu or call 205-434-1502 for more information and to find out if you're eligible.
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The Targeted Exercise for African Americans with Multiple Sclerosis (TEAAMS) study will examine whether a 16-week home-based, racially-tailored exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black/African Americans with MS who live in rural communities in the Southeastern US. Eligible participants must be 18-64 years old, diagnosed with MS, self-identify as Black or African American, and live in the Southeastern US. Participants will be compensated $90 for completing all study visits. Please contact Edson Flores at enrl@uic.edu or (833) 727-1887 for more information and to see if you qualify.
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Then you may be eligible for a research study. If you are female ages 18-49 and were diagnosed with endometriosis in the last 10 years, you may qualify to receive study medication at no cost to you. For more information call 205-934-1322 or email slangan@uabmc.edu. Compensation provided for completed visits.
Published in Clinical Trials
The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5-hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
Published in Clinical Trials
If so, you may qualify for a research study being conducted at the University of Alabama Birmingham. We are seeking people between 45 and 85 years of age to participate in a study of brain and breathing treatments for arthritis pain. The study involves seven visits over a three-week period to the study center at the University of Alabama Birmingham, where clinical tests and brain stimulation treatment will be done, along with brain scanning. Participants will receive $350 for completing the study. If you are interested, please call the PROACT Study at 205-934-9614.
Published in Clinical Trials
The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5 hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
Published in Clinical Trials
The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5 hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
Published in Clinical Trials
Researchers at the University of Alabama at Birmingham are recruiting for studies that examine the effects of Virtual Reality Walking on SCI pain experience. Participants receive between $350 to $400 dollars for study participation. Transportation is reimbursed. Participants must be between the ages of 18 and 65 and have complete paraplegic injury. If you are interested, call the Virtual Reality Walking Study at Dr. Trost’s Research Lab for more information. (205) 934 - 9040
Published in Clinical Trials
The UAB Neuroinflammation, Pain and Fatigue Lab is looking for individuals to take a low dose of naltrexone or a placebo for 6 months. Every participant will receive the drug at some point during the study. You will be asked to come in for a screening session; to complete a daily symptom questionnaire and to provide blood samples during the 6-month period. If eligible, you will be compensated up to $425. Participants must: Have moderate to severe chronic fatigue (for at least 12 months); Not be pregnant or currently planning to become pregnant; Be without any significant medical conditions such as heart disease; and Not currently using opioid medications. For more about this study, call (205) 530-8006.
Published in Clinical Trials