University of Alabama at Birmingham is seeking cigarette smokers who would like to quit smoking for participation in a scientific research study. The research study involves free counseling and treatment provided in a comfortable, supportive setting. The study may involve ingestion of psilocybin, a psychoactive substance found in psychedelic mushrooms that have been used as a sacrament in various cultures. Some research studies have suggested that psychedelics, when administered under interpersonally supportive and well-prepared conditions, may be effective in helping people overcome addictions.

Questionnaires, interviews, and biological measures of smoking will be used to assess the treatment's effects on mood and smoking. Participants will be compensated $50 per session. If you would like to discuss the possibility of volunteering, please call 205-996-1198, or go to www.quitsmokingbaltimore.org for more information about the study and to complete the online study prescreener for the UAB site. Confidentiality will be maintained for all applicants and participants.

Volunteers must be 21 years of age or older, and must live within travel distance of the study site in Birmingham.
There is an ongoing psychedelic clinical research study evaluating the safety and efficacy of an intranasal study drug for patients with treatment resistant depression.

To qualify patients need to be 18-75 years of age, failed to respond to an adequate dose & duration of at least 2 medicines for depression. If currently taking antidepressants, willing and able to discontinue.

If eligible, study participants will be expected to abstain from illicit drugs for the duration of the trial & attend all study visits & follow instructions from the study doctor. Study examinations will be at no cost to you.

For more information please contact 205-996-1198 or spremani@uab.edu
Treatment for Urge Urinary Leakage: BEST Study

This study will compare the effectiveness of two different treatments for urge urinary incontinence (UUI). One treatment is Botox injections in the bladder, and the other is an oral medication (mirabegron or vibegron).

Participants compensated up to $425.

For more information about this study, please email or at urogynecology@uabmc.edu or 205-934-5498.

Are you between the ages of 11-19 with no history of mental health disorders?
Are you physically healthy?
If so, you may be eligible to participate in a study.
Compensation provided.
For more information, please call Brennan Wink at 205-975-4208 or send an
email to Brennanwink@uabmc.edu.

Are you experiencing pain due to endometriosis? Please consider joining a research study looking at a potential new medication to help women experiencing moderate to severe endometriosis-related pain. Study medication provided at no cost. Participants receive compensation for each visit completed. For more information please call 205-934-1322 or email slangan@uabmc.edu.
Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.

We are looking for people with knee osteoarthritis to participate in a study to examine whether a diet intervention can reduce pain and improve quality of life. The commitment to this study will last approximately 7 weeks and include the following:

  • Five (5) visits to UAB where you will fill out questionnaires, complete a DEXA scan, blood draw or Quantitative Sensory testing. These visits will last anywhere from 1-3 hrs.
  • Six (6) weeks on a randomized diet where we will provide three (3) meals and two to three (2-3) snacks per day.

Participants must:

  • Be currently suffering from pain related to knee osteoarthritis
  • Be free from other serious health conditions (diabetes, cardiovascular disease, eating disorders, metabolic disease)

Participants will receive up to $250 for completing the study and meals will be provided. Please contact DIRECT at DIRECTPAIN1@gmail.com (205) 834-3628. Leave a short message with your name and number.

UAB is looking for participants for a study investigating the effects of a new study medication on symptoms of fibromyalgia. We are looking for women aged 25-65 who are diagnosed with fibromyalgia OR are experiencing chronic widespread bodily pain. Participants will come to UAB for 7 study visits over a 3-month period. Participants will be compensated for completing all study visits.

Please call 205-996-1198 if interested.
If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
Then you may be eligible to participate in a study to see if providing healthy, home-delivered meals improves your health and helps you lose weight after having a baby. To be eligible you must be at least 18 years of age, no more than 18 weeks (or about 4 months) post-delivery, Medicaid or WIC eligible, and have received your prenatal care at a UAB clinic. For this study, you will be asked to come to UAB for 2 study visits. If you participate, you will receive 10 study-provided meals per week for a total of 8 weeks. You will be compensated for your time. If you have any questions or to confirm eligibility, please contact Camille Worthington at (205) 975-8873 or Email: cschneid@uab.edu.
UAB researchers are looking for adults (ages 25-65) who are suffering from demoralization - feelings of hopelessness or meaninglessness - to participate in a research study evaluating a novel medication.

To see if you qualify call 205-379-7527.

Help us find out by joining our study at UAB by participating in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB Hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Haley at PRECISION-BPSTUDY@uabmc.edu or call us at 205-975-5825 if you are interested.

Are you tired of constantly fearing urinary leakage? Say goodbye to embarrassing accidents and take control of your life! We believe in living life to the fullest without worrying about Urgency Urinary Leakage. Compensation is provided.

Call us today at (205) 934-5498 to join our urogynecology clinical trial and find the perfect treatment plan tailored to you.
You may be eligible to participate if you identify as female, White or African American, are aged 35-65, and have a BMI of 30+. Participants will receive $50 as thanks for their participation.

This study is a 5-hour workshop delivered in groups that is based on principles of acceptance and commitment therapy (ACT). Participants will learn new skills to facilitate the adoption of healthy lifestyle behaviors, such as eating a healthy diet and exercising regularly. These skills include identifying values, tolerating the discomfort associated with lifestyle change, identifying self-sabotaging thoughts, and more!

For more information, please contact Andrea at andrealdavis@uabmc.edu or 205-206-9434.
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Tiffany at 205-934-0534 or email us at nauticalstudy@uabmc.edu.
Then you may be eligible to participate in a study to see if providing healthy, home-delivered meals improves the health of pregnant moms and their baby. To be eligible you must be at least 18 years of age, no more than 20 weeks gestation, receiving prenatal care at a UAB clinic, and planning to deliver at UAB. For this study, you will be asked to come to UAB for 1 study visit and to complete 1 study visit by phone. If you participate, you will receive 10 study-provided meals per week. You will be compensated for your time. If you have any questions or to confirm eligibility, please contact Camille Worthington at (205) 975-7274 or email cschneid@uab.edu.
Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study investigating the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
We are actively recruiting for research studies focused on women with one of the following conditions:

1. Accidental bowel leakage (fecal incontinence)
2. Urinary leakage (urinary incontinence)

Please call 205-934-5498 to learn more about these studies.
If you are currently pregnant, 18 or older, planning to deliver at UAB, and planning to breast feed, you may be eligible for our study!

This study focuses on better understanding breast milk composition, the presence or absence of CMV in breast milk, and its possible transmission to babies. CMV is a common virus that most people in the US are infected with by adulthood. Participants will meet with study staff once a month for six months to collect non-invasive samples and answer a questionnaire. Samples collected include oral swabs from you and your baby, a small quantity of breast milk and a skin swab from you, as well as a urine and stool sample from your baby. Participants will be compensated up to $300 for completing the study visits and providing samples. Eligible participants may also qualify for additional sub-studies for additional compensation up to $800.

For more information, please contact us via phone or email at:
Phone: 205-975-3752
Email: milk@uabmc.edu
If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
This research study will look at a certain part of the immune system, called the complement system, as it relates to a hormone called estradiol. We will compare the components of your tears and blood to see how the complement system is affected by estradiol in women across different ages. We will also use some cells gently collected from the front of your eye to see how proteins of the complement system are made. We will use your tears, blood, and cells for testing if you agree to donate them to the study. The study will enroll 48 women between the ages of 35 and 64. Eligible participants will receive compensation for their time. To find out more about the study, kindly email us at: SOeyes@uab.edu
Are you a HIV negative, generally healthy adult between the ages of 18-55?
The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study is to evaluate the safety and immunogenicity of synthetic DNAs encoding in adults without HIV. This trial is in search of healthy HIV negative adults between the ages of 18-55. Procedures will include blood draws and injections of study vaccine, as well as the collection of white blood cells. White blood cells will be collected by a procedure called leukapheresis. Participants will be compensated for their efforts in this study.

If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles sugar. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
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