Do you have a family member diagnosed with RA or do you think you are at risk of developing RA? If so, you may be eligible to participate in a research study about the possible prevention of RA. Must be at least 18 years or older without a prior diagnosis of RA. For more information, please call 205-934-9843 or email lplove@uabmc.edu
You may be eligible for the TWEAK Trial. A randomized clinical trial at UAB to determine if strength training rehabilitation improves recovery after joint replacement. Participants receive free health and functional status monitoring, free body composition and fitness testing, $500 for participation, and free personal exercise testing (half of the participants). Supervised exercise training program with certified trainers (half of participants): 3 days per week for 16 weeks at the Exercise Clinical Trials Facility at UAB. For more information, please call 205-934-6231.
If you ages 18 and older AND have either heart failure (in the past 2 years) or a heart attack (in the past year) you may qualify for a research study. What happens in the study? • vaccination with either high dose (investigational for adults under the age of 65) OR standard dose flu shot, provided at no cost to you (once per year, up to 3 years); •monitoring any heart or lung related hospital visits; • telephone follow-up • optional blood draw. Patients who have already received their flu shot this year are not eligible to enroll. Participants will be compensated. For more information about how you can participate in INVESTED, please call the UAB Hypertension Program at 205-934-9281.
Are you feeling sad, down, hopeless? Feeling guilty? Experiencing loss of interest in activities? Having difficulty concentrating? Sleeping too little or too much? 19-70 years old? In good physical health? If so, you may be eligible to participate in a research study. For more information, please call UAB Office of Psychiatric Research at 205-934-8336.
The UAB Neuroinflammation, Pain and Fatigue Lab is looking for individuals to take part in a research study. We will induce a temporary immune response and test how this affects fibromyalgia symptoms and markers of immune activity. You will be asked to come in for a screening session and, if eligible, two experimental sessions. You will be compensated up to $1025. Participants must have fibromyalgia, not be pregnant or currently planning to become pregnant, be without any significant medical conditions such as heart disease, and not currently using opioid medications. To find out more about this study, please call (205) 530-8006.
Our study is currently recruiting single primary caregivers of a 3-8 year old child to fill out 2 questionnaires about health and weight. Eligible participants will be compensated $10 for their time. Call 205-975-7721 for more information or to see if you are eligible to participate.
You may qualify to participate in a national research study to evaluate the safety and effectiveness of the shingles vaccine (Zostavax®). Are you at least 50 years old? Are you taking Remicade, Enbrel, Humira, Cimzia or Simponi? If yes, and if you have never received the shingles vaccine, you may qualify. The duration of the study is 6 months. Participants will be compensated. Zostavax ® is an approved vaccine for people ages 50 and older and has been shown to be very effective to prevent zoster (shingles) and related complications. However it has NOT been studied in patients who are taking Remicade, Enbrel, Humira, Cimzia or Simponi. The Varicella zostER VaccinE Study (VERVE) has been approved by the Food and Drug Administration (FDA). UAB is coordinating the VERVE study. For more information, please call (205) 934-2993 or email verve@uab.edu
Healthy African American or Caucasian men and women ages 18-40 needed to participate in a research study about the effects of glucose on a protein in your blood — this protein is related to heart disease. Must have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please email Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
If you have been diagnosed with gout, you may qualify to participate in one of our Gout research studies. Treatment and compensation for your time is provided per study visit. Please call Stephanie at 205-934-1444 or sbiggers@uabmc.edu.
If you are age 18 or older and healthy (not suffering from any serious clinical condition) you may be eligible to participate in a study to determine bioenergetic health. Participants will answer a short questionnaire and have blood collected (20ml ie. 2-3 tubes). Compensation ($25) after blood draw will be provided per study visit. For more information, please email mitolab@uabmc.edu.
Are you a healthy person ages 18-40? You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians and have no history of diabetes, heart problems, or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
You may be eligible to participate in a research study about the effects of glucose on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians and have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
The UAB Division of Rheumatology and Immunology is conducting a study to research the effects of Rheumatoid Arthritis on muscle strength and insulin. To qualify, you must be between the ages of 35 and 65, not be diagnosed with diabetes or any other illness that may impair evaluation of study outcomes, and do not engage in a strength training program or vigorous exercise. All participants will be required to come to UAB for testing on 3 or more occasions and qualified RA participants will receive a 15-week regimen of the study drug. There is no charge for participation and all participants will receive compensation. For more information, and to see if you might be eligible to join, call (205) 934-4021.
UAB is currently offering a NO-COST research treatment program for those who want to stop using cocaine. This study combines medication and counseling treatment. If you use cocaine and would like to stop, please call UAB at (205) 975-7721.
Are you a breast cancer survivor having difficulty walking? Do you have any lower-body pain that is restricting your mobility? If so, you may be interested in taking part in an exercise training intervention. UAB researchers are looking for overweight women  - age 18-70 with a body mass index between 30-45 kg/m2 - with a history of breast cancer to participate in a novel exercise training study. Volunteers will be asked to attend two assessment sessions: an initial assessment and after 8 weeks of exercise to collect information about your health status. Further eligibility screening will be conducted by telephone. Volunteers must reside in or near Jefferson County. The study will evaluate a novel exercise training strategy designed to mimic exercise at higher altitude to support improved health and mobility among breast cancer survivors. Contact Dr. Stephen J. Carter, 205-975-0269 or carters@uab.edu; or the UAB Exercise and Cancer Research Team, 205.934.5466 or moveforward@uab.edu; to learn more.
We are looking for healthy older adults who are interested in participating in a study about healthy aging. You may be eligible if you have no major physical disabilities, are independent in basic life activities, and are 85 years or older. Participants will be compensated. Call 205-975-7017 for more information and to see if you qualify.
The UAB Neuroinflammation, Pain and Fatigue Lab is looking for individuals to take a low dose of naltrexone or a placebo for 6 months. Every participant will receive the drug at some point during the study. You will be asked to come in for a screening session; to complete a daily symptom questionnaire and to provide blood samples during the 6-month period. If eligible, you will be compensated up to $425. Participants must: Have moderate to severe chronic fatigue (for at least 12 months); Not be pregnant or currently planning to become pregnant; Be without any significant medical conditions such as heart disease; and Not currently using opioid medications. For more about this study, call (205) 530-8006.
If you are 18-65 years old, have a child 12-65 willing to participate in the study with you, generally healthy, with or without history of early life trauma you may be eligible to participate in a research study to explore whether you can pass along your stress to your children. Compensation provided: parents $100/children $25. For more information and to determine eligibility, please call Katlyn at 975-4208.

Are you ages 18-75? Are you currently taking medication specifically for Pulmonary Arterial Hypertension, also known as Pulmonary Hypertension? You may qualify for participation in the ongoing LIBERTY research study. If you would like more information, please contact the UAB Cardiovascular Clinical Trial Unit, 205-975-9964.

We are currently seeking individuals diagnosed with spinal cord injury (SCI) for a research study evaluating diet. The purpose of this study is to determine if a low carb or low fat diet is better for helping adults with SCI: 1) stick to their diet, 2) improve their body composition, and 3) lower their cardiometabolic risk factors (such as diabetes, heart disease, or stroke). This study is for adults with SCI ages 21-60. Participation is free, and compensation is provided. For more information, please call Ashley Sineath at 205-403-5510 or email at asineath@uab.edu
You could be a candidate for a research study evaluating a new procedure for treating high blood pressure. Are you age 18-75? Are you willing to stop or change your current blood pressure medicine for a short time if supervised by a doctor? If yes and you want more information regarding the RADIANCE-HTN STUDY, please contact the UAB Hypertension Clinic at bloodpressure@uab.edu. Participants will be reimbursed for travel and study visits expenses.
ASPIRE is a National Institutes of Health (NIH) study that compares three surgical procedures that are currently used to repair vaginal prolapse.  Women who have had a hysterectomy, feel or see a vaginal bulge and desire further evaluation may be eligible. For more information, call 934-5498. Compensation is provided.
We are currently seeking cardiac surgical patients to participate in the LEVO-CTS research study. The purpose of the study is to evaluate an investigational drug with the potential to improve outcomes in patients undergoing coronary artery bypass and/or heart valve surgery. Minimum eligibility requirements: Must be 18 years or older, your physician has diagnosed you with coronary vessel disease requiring bypass surgery and/or the need for heart valve surgery. Talk to your cardiologist or your heart surgeon for additional information. Questions can also be answered by Alicia Kindred or D'Netria Jackson at 205-934-4711 or 205-975-2088.

This study will examine the effectiveness of a group exercise class on the health and function adults age 18-65 with a history of stroke. You will be randomly assigned to one of two groups; Movement2Music or a waitlist group who will complete a home-based exercise intervention. Email caseyh@lakeshore.org or call 205-313-7455 for more information. Participation is free, and compensation is provided.

In our study of patients with resistant hypertension, we have shown that vascular function improves with the use of spironolactone, a mineralocorticoid receptor antagonist. Spironolactone has also been shown to reduce urinary protein loss in patients with chronic kidney disease. We are looking for men and women, ages 19-65, with Stage III CKD, non-diabetic or who have controlled diabetes, and who are not currently taking spironolactone or amiloride. The study lasts 16 weeks, with six visits, and compensation and parking will be provided for all six visits. If interested, please contact Cassidy Clevenger at (205) 934-6745.
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