Inflammation, infection, and immunity (I3) impact almost all diseases studied and treated at UAB. I3 integrates the expertise and resources at UAB to build unified, interdisciplinary programs in inflammation-based, fundamental and clinical research.

In basic science, I3 seeks to define the fundamental mechanisms regulating inflammation in all organ systems and in response to stimuli beyond infection. It also emphasizes a comprehensive (systems biology) approach to studying inflammation. I3 integrates technology to characterize inflammatory responses across multiple tissues and disease states.

In translational science, I3 enhances our ability to rapidly translate the data on fundamental mechanisms into clinical interventions to prevent, treat, and modulate inflammation in the settings of disease, vaccination, and therapy, emphasizing personalized and population-based approaches to treatment. I3 research translates into clinical trials that span multiple disease settings. I3 integrates data to develop personalized inflammatory signatures across multiple tissues and disease state, as well as across different patient populations.

The Immunology Institute (II) serves as a central focal point for coordinating immunologic research, which by its very nature is spread across disciplines such as microbiology, cell biology, transplantation, pediatric and adult medicine, oncology, pathology, and many more. The II is a point of contact for those interested in immunology education and outreach–both on the UAB campus and within our community and state. Furthermore, it serves to bring researchers across disciplines together for greater collaboration—a distinguishing attribute of UAB.

Frances Lund, Ph.D., Charles H. McCauley Professor and Chair of the Department of Microbiology, serves as the founding director of the II.