Clinical History
A 28 year old male presents with gross hematuria after a trip abroad. Cystoscopy and biopsy are performed.
Choose the Correct Diagnosis:
- Schistosomiasis with reactive urothelium
- Schistosomiasis with Carcinoma in situ
- Schistosomiasis with Eosinophilic cystitis
- Schistosomiasis with invasive urothelial carcinoma
Answer: 1.
Discussion:
Schistosomiasis eggs are present. The urothelium shows uniform nuclear enlargement, maintained polarity and prominent nucleoli, consistent with reactive urothelium. Numerous eosinophils are a common finding in cases of schistosomiasis but can also be a non-specific finding in many conditions that cause chronic irritation of the bladder.
Contributed by Jennifer Gordetsky, M.D., Associate Professor, UAB Department of Pathology