Case of the Week
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Resection of a 3.5 cm subcutaneous mass from the left hand of a middle-aged man is depicted. What is the most likely cytogenetic abnormality in this tumor? (Brief History)
- t(11;22)
- t(9;22)
- t(7;16)
- t(12;16)
Contributed by Dr. Shi Wei
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Choose the correct diagnosis:
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Clinical History:
66 year old male s/p kidney transplant with pericardial effusion
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Clinical History:
41 year old pregnant female with invasive cervical squamous cell carcinoma underwent cesarean section delivery, hysterectomy and lymph node dissection. Sections from the cervix confirmed the presence of invasive squamous cell carcinoma. Right obturator lymph node shows the following.
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The patient is a 60 year old female with left breast mass, who underwent needle localized lumpectomy.
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What is the most likely diagnosis? A. Invasive ductal carcinoma. |
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57 year-old male with varices. Gastric biopsy.
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What is the most likely diagnosis? A. Helicobacter Pylori-related peptic ulcer |
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Uterine mass in a 45 year old woman.
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What is the most likely diagnosis? A. Papillary squamous cell carcinoma |
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This placental lesion an example of (Figure 1)
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What is the most likely diagnosis? A. 1⁰ placental choriocarcinoma |
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A 58 Y/O male h/o HBV, HCV, decompensated alcoholic cirrhosis and renal dysfunction (unclear etiology) who presented for consideration of orthotopic liver transplant and deceased donor renal transplant. Most recent End-Stage Liver Disease (MELD) score at last clinic visit was 24. He No encephalopathy. Denies h/o kidney or liver biopsy. Abdominal MRI revealed cirrhotic liver without focal lesion identified within the limitations of this examination due to given large volume of ascites. Macroscopic examination of the native liver weighted 983 g and 19.7 x 18.3 x 8.3 cm. The external surface of the liver is tan-brown and nodular. The cut surface is tan-brown to red-brown and diffusely nodular (ranging from 0.1-0.3 cm). In the left lobe, there are numerous (>30) tan-yellow soft ovoid nodules ranging from 0.1-0.9 cm in greatest dimension.
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What is the most likely diagnosis? A. Focal Nodular Hyperplasia (FNH). |
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A 19-year-old female with a 7.8 cm heterogeneously enhancing mass that was found on imaging after patient was in MVC. No personal or family history of liver disease, contraceptive use, hepatitis, or other malignancy. No significant unintentional weight loss or jaundice. MRI of the abdomen showed 7.3 x 6.2 cm lesion with lobular margins and several punctate calcifications within the central aspect of this lesion Figure (1). The patient underwent partial hepatectomy. Macroscopic examination revealed 8 x 6.3 x 6 cm tan-yellow firm ovoid mass. The remaining cut surface of the liver is red-brown and soft.
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What is the most likely diagnosis? A. Focal Nodular Hyperplasia (FNH) |