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By taking part in a clinical trial at UAB, you can play a vital role in UAB's internationally renowned research enterprise. You can also join ResearchMatch, a multi-institution project that pairs volunteers with researchers seeking study participants.

By alternating high-salt and low-salt diets, a new clinical trial aims to find out how common salt sensitivity of blood pressure is in the general population. The researchers are also exploring whether the immune system plays a role.

Do you have Type 2 Diabetes? Are you 18 years or older? Not currently taking Insulin ? Are you currently being treated with stable doses of daily or weekly GLP-1 receptor agonist, the treatment can be with or without any of the following anti-diabetic drugs with stable doses: Metformin, Sulfonylureasa , Meglitinides (glinides), DPP-4 inhibitors, Sodium-glucose co-transporter 2 inhibitors, Alpha-glucosidase-inhibitors, Thiazolidinediones The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 52 week research study comparing the efficacy and safety of once weekly IcoSema and once weekly semaglutide, Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.

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Do you have Type 2 Diabetes? Are you 18 years or older? Not currently taking Insulin? Are you currently being treated with stable doses of daily or weekly GLP-1 receptor agonist? This 52 week research study is seeking qualified participants to help compare the efficacy and safety of once weekly IcoSema and once weekly semaglutide. Qualified participants will receive study drug free of charge and may be compensated for time and travel. The treatment can be with or without any of the following anti-diabetic drugs with stable doses: Metformin, Sulfonylureasa , Meglitinides (glinides), DPP-4 inhibitors, Sodium-glucose co-transporter 2 inhibitors, Alpha-glucosidase-inhibitors, and Thiazolidinediones. For more information, and to see if you might be eligible to join, please contact 205-996-4015 or email at ccnrn@uab.edu.
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Adults with Type 2 Diabetes needed for a study If you are between the ages of 18 -89 yrs and have type 2 diabetes you may be eligible to participate in a study exploring the reason why individuals who have diabetes have an increased risk of forming calcium oxalate kidney stones. Individuals who are obese, overweight, or normal weight are all welcome to the study. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information, call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu.

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You may be eligible to participate in the UAB’s Cardiovascular Research Biobank (CARBON), a repository of biological samples that will be used for future research about heart disease, diabetes, genomics, and more. Participants must be over the age of 18. The study will require one brief visit to UAB and collection of blood samples. Participants will be compensated. Please contact Nehal Vekariya at carbonstudy@uabmc.edu or 205-934-7173 if you are interested.

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Clinical trial investigates diet as a way to remodel the body by re-partitioning energy away from metabolically harmful lipid stores.
Are you taking Metformin alone or metformin with a sodium-glucose transport protein 2 (SGLT2) inhibitor to treat your diabetes? The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 39-week research study to see how two new study medicines work together on blood sugar levels in people with Type 2 diabetes. Qualified participants will receive study-drug free of charge and may be compensated for time and travel. For more information, and to check your eligibility to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking sacubitril/valsartan or valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Vibhu Parcha, vparcha@uabmc.edu if you are interested. 
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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a research study to evaluate the effectiveness of an investigational drug to treat people with Type 2 Diabetes and obesity. To qualify, you must have Type 2 Diabetes, older than 18 years old, moderately overweight, diet-controlled or taking oral diabetes medications. Qualified participants will receive the study drug free of charge and compensation for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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We are looking for adults with type 2 diabetes for a research study to see if eating large amounts of whole fruit can improve your blood sugar and reduce your need for diabetes medications. You may be eligible if you are 20-65 years old, overweight (BMI 27-45), diagnosed with type 2 diabetes within the last 6 years, and are not taking insulin. Participants will be provided with meals for 12 weeks, a high-speed Vita-Mix blender, and $1,375 for completing the study. Since this study is time-intensive, we are seeking only highly motivated and dedicated participants. If you are interested, please complete the brief electronic form at http://bit.ly/fruit_study. For more information, please contact Cody Hanick at chanick@uab.edu or (262) 923-0672.
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We are looking for adults with type 2 diabetes for an exciting research study to see whether intermittent fasting and/or using light therapy can improve your blood sugar, improve your overall health, and reset your body clock. Participants will either eat early in the day, graze throughout the day, and/or use a special light therapy box or glasses. You may be eligible if you have type 2 diabetes, are 30-80 years old, are not taking insulin, and usually wake up between 5:00 and 9:00 am. The main part of the study lasts 16 weeks and involves two overnight tests in our clinic (which can be done on weekends, if preferred). Participants will receive $2400 for completing the study. 

If you are interested, please follow the link http://bit.ly/clocksstudy  to apply for the CLOCKS study. Or for more information, please contact our research team for more information: Errin Jessie or Kimberly Armstead at CLOCKSSTUDY@uab.edu or 205-975-3944 or 205-934-6202.

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UAB Department of Nutrition Sciences is conducting a nutrition study looking at the effects of diet in adults with type 2 diabetes, high blood sugar, for less than 5 years. You may qualify if you are between the ages of 35-65, are African American or European American, are not using insulin, and are willing to travel to UAB for testing visits. Qualified participants will receive weekly groceries, personal health information, group support sessions with a Registered Dietitian, and monetary compensation for your time. For more information and to see if you qualify, please call 205-934-4386 or email LLG@uab.edu.
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We are seeking volunteers with Type 2 Diabetes for a weight loss research study looking at the role of dietary protein in weight loss and the remission of type 2 diabetes. The study will last approximately 12 months. Participants will participate in a 16 week State of Slim group weight loss program and a 36 week State of Slim Next Steps weight loss maintenance program, with body composition scans and lab work at no charge. Participants will receive monetary stipends of $300 to reimburse for time and travel to study classes and study visits. You may qualify for this weight loss research study if you are nonvegetarian, 18 years of age or older, has Type 2 Diabetes diagnosed within the last 6 years, are overweight or obese with a BMI greater than or equal to 27. Must be willing to participate in weekly group weight loss classes for 16 weeks, bi-weekly weight loss maintenance classes for 36 weeks, and attend four study visits over 12 months at the Lakeshore Foundation Campus. Also is willing to regularly consume lean red meat or not consume any red meats. Please call (205)873-8241 or email cwyoder@uab.edu if you are interested.
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The UAB Department of Nutrition Sciences is conducting a nutrition study looking at the effects of diet in Type 2 diabetes. You may qualify if you are ages 35-65, are African American or European American, have been diagnosed with Type 2 diabetes within the past 5 years, and are willing to travel to UAB for testing visits. Qualified participants will receive weekly groceries, personal health information, group support sessions with a Registered Dietitian, and monetary compensation for your time. For more information and to see if you qualify, please call 205-934-4386 or email LLG@uab.edu.
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Participants needed for the ACES Trial - Antihypertensives Combined with Exercise for Seniors with Hypertension. This is a randomized, controlled trial (RCT) to determine if choice of antihypertensive medication influences changes in functional status and other cardiovascular risk factors among older persons with hypertension. Sedentary men and women > 60 years of age with functional limitations and hypertension will be recruited from two sites to participate in a longitudinal intervention trial. Participants will be randomly assigned to one of three first-line antihypertensive agents and participate in a structured aerobic exercise intervention. This study is expected to differentiate beneficial effects of three FDA-approved antihypertensive medications on established and emerging cardiovascular risk factors in a clinically-relevant population. For more information, call 205-996-3005 or apply online.
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Healthy African American or Caucasian men and women ages 18-40 needed to participate in a research study about the effects of glucose on a protein in your blood — this protein is related to heart disease. Must have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please email Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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You may be eligible to participate in a research study about the effects of glucose on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians and have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
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The UAB Division of Rheumatology and Immunology is conducting a study to research the effects of Rheumatoid Arthritis on muscle strength and insulin. To qualify, you must be between the ages of 35 and 65, not be diagnosed with diabetes or any other illness that may impair evaluation of study outcomes, and do not engage in a strength training program or vigorous exercise. All participants will be required to come to UAB for testing on 3 or more occasions and qualified RA participants will receive a 15-week regimen of the study drug. There is no charge for participation and all participants will receive compensation. For more information, and to see if you might be eligible to join, call (205) 934-4021.
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You may qualify to participate in an international research study to evaluate the safety and tolerability of an investigational drug for patients with type 2 diabetes and kidney disease. Are you at least 18 years old? Do you have type 2 diabetes mellitus and a clinical diagnosis of kidney disease? Eligible study participants will receive study medications, blood pressure checks, physical exams, laboratory tests and ECG at no cost. Participants will  be reimbursed for time and travel. For more information, call the UAB Hypertension Program at 934-9281 or e-mail ccc-hlnresearch@mail.ad.uab.edu.
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