Mental exercises may help some people think faster and better. This study seeks to examine whether the amount of such mental exercises can help people think better. All information is confidential and you will be compensated $100 for the first visit; other visits with compensation may follow. To qualify, you must be 40 or older, be HIV-positive & diagnosed for at least 1 year, speak English, and be a patient at the UAB 1917 Clinic. For more information, please contact (205) 996-0196.
The TOPS Study seeks to examine whether the amount of such mental exercises can help people think better. All information is confidential and you will be compensated $50 for the first visit; other visits with compensation may follow. To qualify, you must be 40 or older, HIV-positive — diagnosed for at least 1 year — and speak English. For more information, please contact (205) 934-6174.
You may qualify for a research study in the UAB Department of Psychiatry and Behavioral Neurobiology if you have never been diagnosed with a mental illness. Call 975-4207 for more information. Compensation provided.
You may be eligible to participate in a research study about the effects of glucose on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasians and have no history of elevated blood pressure, diabetes, heart problems or kidney problems. The study involves consuming prepared meals and collecting blood samples. Participants will be compensated. Please e-mail Dr. Nirav Patel, npatel@uabmc.edu if you are interested.
You may qualify for a research study in the UAB Department of Psychiatry and Behavioral Neurobiology. Call 975-4207 for more information. Compensation provided.
You may be eligible for the TWEAK Trial. A randomized clinical trial at UAB to determine if strength training rehabilitation improves recovery after joint replacement. Participants receive free health and functional status monitoring, free body composition and fitness testing, $500 for participation, and free personal exercise testing (half of the participants). Supervised exercise training program with certified trainers (half of participants): 3 days per week for 16 weeks at the Exercise Clinical Trials Facility at UAB. For more information, please call 205-934-6231.
Are you concerned about your bone and joint health? Men and women age 45-69 are needed for a Bone and Joint Health Study, a study about how physical activities and other factors affect the health of your bones and joints.  Compensation is provided.  Call 205-975-7223, Option 2 for more information!
Are you feeling sad, down, hopeless? Feeling guilty? Experiencing loss of interest in activities? Having difficulty concentrating? Sleeping too little or too much? 19-70 years old? In good physical health? If so, you may be eligible to participate in a research study. For more information, please call UAB Office of Psychiatric Research at 205-934-8336.
There is a clinical study at UAB enrolling people with depression. If you have a history of depression or are currently depressed, please call us at 934-8336 for screening and enrolling. You will be compensated up to $120 if you complete the study.
We are currently seeking cardiac surgical patients to participate in the LEVO-CTS research study. The purpose of the study is to evaluate an investigational drug with the potential to improve outcomes in patients undergoing coronary artery bypass and/or heart valve surgery. Minimum eligibility requirements: Must be 18 years or older, your physician has diagnosed you with coronary vessel disease requiring bypass surgery and/or the need for heart valve surgery. Talk to your cardiologist or your heart surgeon for additional information. Questions can also be answered by Alicia Kindred or D'Netria Jackson at 205-934-4711 or 205-975-2088.
If you are 18-65 years old, have a child 12-65 willing to participate in the study with you, generally healthy, with or without history of early life trauma you may be eligible to participate in a research study to explore whether you can pass along your stress to your children. Compensation provided: parents $100/children $25. For more information and to determine eligibility, please call Katlyn at 975-4208.
You may qualify to participate in a national research study to evaluate the safety and effectiveness of the shingles vaccine (Zostavax®). Are you at least 50 years old? Are you taking Remicade, Enbrel, Humira, Cimzia or Simponi? If yes, and if you have never received the shingles vaccine, you may qualify. The duration of the study is 6 months. Participants will be compensated. Zostavax ® is an approved vaccine for people ages 50 and older and has been shown to be very effective to prevent zoster (shingles) and related complications. However it has NOT been studied in patients who are taking Remicade, Enbrel, Humira, Cimzia or Simponi. The Varicella zostER VaccinE Study (VERVE) has been approved by the Food and Drug Administration (FDA). UAB is coordinating the VERVE study. For more information, please call (205) 934-2993 or email verve@uab.edu
The Neuroinflammation, Pain and Fatigue Lab is currently looking for Veterans of the Persian Gulf War to participate in our research studies.  If you are male, between the ages of 39-65, and were present in the Persian Gulf between 1990-August 1991, you may be eligible to participate in one of our new research studies.  Veterans with Gulf War Illness, healthy Gulf War Veterans, and individuals with Fibromyalgia/ Chronic Fatigue Syndrome are all needed. Compensation is provided. For more information, call 256.400.3631 or email GWI@uab.edu. You may also fill out our online screening questionnaire.
If you are age 18-40, you may qualify to participate in a 14-week study for borderline high blood pressure. Eligible participants receive study medication, blood pressure checks, and lab tests at no cost. Participants are compensated up to $325 for completed visits. Call Eve at 205-975-7001 to schedule a screening visit.
The UAB Office of Psychiatric Research is conducting a study examining the relationship between early life stress, depression, and glucose metabolism. In order to qualify, you must have no history of anxiety, psychosis, mania, substance dependence within a year. You must also have no history of endocrine, cardiovascular, or inflammatory diseases. To see if you may qualify, please call (205) 975-4207.
If you ages 18 and older AND have either heart failure (in the past 2 years) or a heart attack (in the past year) you may qualify for a research study. What happens in the study? • vaccination with either high dose (investigational for adults under the age of 65) OR standard dose flu shot, provided at no cost to you (once per year, up to 3 years); •monitoring any heart or lung related hospital visits; • telephone follow-up • optional blood draw. Patients who have already received their flu shot this year are not eligible to enroll. Participants will be compensated. For more information about how you can participate in INVESTED, please call the UAB Hypertension Program at 205-934-9281.
You  may qualify to participate in a national 8-week research study to evaluate the safety and efficacy of an investigational medication to treat patients with resistant hypertension. Are you 40-85 years old? Do you have high blood pressure? Eligible study participants will receive study medications, blood pressure checks, study related physical exams, laboratory tests, ABPM and ECG at no cost. Participants will be compensated. For more information, please call the UAB Hypertension Program at (205) 934-9281 or e-mail ccc-hlnresearch@mail.ad.uab.edu.
You could be a candidate for a research study evaluating a new procedure for treating high blood pressure. Are you age 18-75? Are you willing to stop or change your current blood pressure medicine for a short time if supervised by a doctor? If yes and you want more information regarding the RADIANCE-HTN STUDY, please contact the UAB Hypertension Clinic at bloodpressure@uab.edu. Participants will be reimbursed for travel and study visits expenses.

Are you ages 18-75? Are you currently taking medication specifically for Pulmonary Arterial Hypertension, also known as Pulmonary Hypertension? You may qualify for participation in the ongoing LIBERTY research study. If you would like more information, please contact the UAB Cardiovascular Clinical Trial Unit, 205-975-9964.

You may qualify to participate in an international research study to evaluate the safety and tolerability of an investigational drug for patients with type 2 diabetes and kidney disease. Are you at least 18 years old? Do you have type 2 diabetes mellitus and a clinical diagnosis of kidney disease? Eligible study participants will receive study medications, blood pressure checks, physical exams, laboratory tests and ECG at no cost. Participants will  be reimbursed for time and travel. For more information, call the UAB Hypertension Program at 934-9281 or e-mail ccc-hlnresearch@mail.ad.uab.edu.
A 24-month research study is being conducted by the UAB School of Dentistry to determine the effectiveness of a commercially available tooth colored dental filling materials bonded on the sides of teeth with three adhesives. Enrollment in the study requires that the subject be available for the 24-month study period. Screening appointments now are available and subjects needing fillings on the sides of their teeth are likely candidates. The fillings are free and a monetary incentive is paid at each recall visit. To determine if you are eligible for this study, call LaTara 996-5747.
The UAB Department of Nutrition Sciences is conducting a research study to evaluate the effectiveness of an investigational drug to treat Type 2 DM. To qualify, you must be 18 years old or older, diagnosed with type 2 diabetes, kidney disease and have risk factors for a cardiovascular event (such as heart attack and stroke). Qualified participants will receive study drug, diet/exercise counseling, EKG, physical and diabetic supplies. There is no charge for participation. Compensation for time and travel may also be available. For more information, and to see if you might be eligible to join, please contact (205)975-8217 or (205)996-4020.
Local physicians are part of a larger clinical trial utilizing an investigational medical device for people with post-amputation pain. If you are experiencing moderate to severe post-amputation pain not controlled by medication, we invite you to learn more. Qualifications for the study include: one amputated lower limb; frequent and recurring amputation pain; willingness to undergo implant surgery; and age 21 or older. For participation information, please email aliciakindred@uabmc.edu, jpough@uabmc.edu or call 934-4711 or 975-2847 to speak with Alicia Kindred (Study Coordinator) or Joseph Pough (Research Assistant).
You may be able to take part in a research study if you: Are ages 18-75; have been diagnosed with Bipolar I or Bipolar II disorder; are currently having a major depressive episode that started at least 2 weeks ago, but no more than 6 months ago; have previously had at least 1 bipolar manic episode or mixed episode (if you have bipolar I) or hypomanic episode ( if you have bipolar II). For more information and to determine your eligibility, please contact Allison at 205-975-2911. Compensation is provided.
If you are ages 18-50, HIV-negative and in general good health, you may qualify to participate in an investigational HIV vaccine study comparing immune responses in two different vaccine regimens. You CANNOT get HIV by receiving the vaccine. Compensation is provided after enrollment for eligible participants. For more information, or to see if you qualify, please call 205-996-4099.
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research match

By taking part in a clinical trial at UAB, you can help generate knowledge that will change the world. Volunteers play a vital role in UAB's internationally renowned research enterprise.

You can also join ResearchMatch, a multi-institution project that pairs volunteers with researchers seeking study participants.

Trials currently available at UAB are listed above; click the tags to refine the list or search for a specific trial. To submit a trial for inclusion in this list, click here.