If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.
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The RECOVER study was designed in partnership with many of the nation’s top experts in treatment-resistant depression, and approved by Medicare, to provide additional evidence of the benefit of VNS Therapy. If the results confirm previous studies, Medicare and other insurers may start to cover it.

People who participate in RECOVER will receive VNS Therapy and all study-related care at no cost to them.

To join the RECOVER study, you must be 18 years or
older and:

1. Currently depressed
2. Have depression, or bipolar depression, that has lasted for at least two years or recurred several times
3. Have tried at least four types of antidepressant treatments and not found them helpful
4. Have Medicare Insurance
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We are currently seeking Gulf War Veterans to participate in a brain imaging research study. Healthy Gulf War Veterans and Veterans with chronic health problems are invited to participate. Participation involves 1-2 visits to UAB for 2.5 hours total. Participants undergo MRI brain scan, blood draw, and complete several questionnaires. Participants who complete the study receive $150 compensation. Please email chloej@uab.edu or call 205-434-1502 for more information and to find out if you're eligible.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy African American men having no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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You may be eligible to participate in a research study looking at the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure and is safe to take with or without hypertension. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart disease or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $675 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.

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The UAB Department of Dermatology is seeking people for a clinical study looking into ultraviolet light induced effects on the skin immune responses. This study may provide clues for the prevention of skin cancer. We are seeking 18-35 year old individuals, without a history of skin cancer, who are capable of being sunburned and who are not currently pregnant or planning to become pregnant the next 2 months. Participants may receive up to $500 in compensation. Please contact 205-801-8841 or UVstudy@uabmc.edu for more information.
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The Alabama Vaccine Research Clinic at UAB are seeking volunteers for a phase 1 HIV prevention study. This study tests the body’s immune system response to, a protein similar to what is found in HIV. The immune response prepares the body to recognize the same protein in HIV and fight the virus if a person is exposed to HIV in the future. Participants will be compensated over $750 for their efforts.

If you are interested, please call 205-934-6777 or email avrc@uabmc.edu.
You can also fill out our contact form at https://sites.uab.edu/avrc/contact-us/
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If you are 18 or older with a BMI of 35 or greater, a history of calcium oxalate kidney stones, and are desiring to lose weight, you may be eligible to participate in a research study. The goal of this study is to better understand calcium oxalate kidney stone disease and how weight loss might impact urinary oxalate and kidney stone risk. The study requires eating a study diet for 5 days with a one-day long visit both before and after weight loss, participating in a 14-week long weight loss program with the aid of Optifast VLCD® shakes, collecting 24-hr urines, blood samples, and stool samples. Participants will have the opportunity to be compensated up to $920 for participation in the program over the 6 -8-month participation time frame. They will also receive all Optifast products and study meals for free! For more information email kidneystoneresearch@uabmc.edu
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Receive compensation and Free 20-Week Exercise Program.

Eligible enrolled participants will receive:
- Supervised exercise training at no cost
- Blood pressure medication at no cost
- Convenient parking at no cost
- Compensation for time

If you are interested, please call 205-996-3005 and mention The ACES Study or apply here -https://www.uab.edu/medicine/exercise/volunteer-clinical-trials/aces-trial.
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The University of Alabama at Birmingham, Department of Family and Community Medicine, is conducting a 12-month research study to test the effectiveness of a diabetes management intervention. If you have type 2 diabetes, are 18 years or older, and self-identify as Black or African American, you may be eligible to participate. Participants will be compensated up to $300 for completing the study.

For more information, please contact us at: 205-224-2567, or freedom@uabmc.edu, or fill out this pre-screening form and we will get in touch with you: https://redcap.link/freedom
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Gastric bypass surgery may increase the risk of calcium oxalate kidney stones and having a bacterium in our intestines that degrade oxalate may reduce the risk of forming kidney stones. For this study, adult Volunteers ages 18-75 are needed to examine whether or not individuals with a history of bariatric surgery can be successfully colonized with Oxalobacter formigenes, a normal gut oxalate degrading bacterium, and if colonization results in a decrease in urinary oxalate excretion. This study involves consuming prepared meals of your choice over 2 days twice, a one-hour long visit to the Clinical Research Enterprise (CRE) and providing stool and urine samples. Compensation up to $420. For more information email kidneystoneresearch@uabmc.edu.
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Help us find out by joining our study at UAB. You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must have a BMI: 30-45 kg/m2), have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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The Targeted Exercise for African Americans with Multiple Sclerosis (TEAAMS) study will examine whether a 16-week home-based, racially-tailored exercise training program can provide improvements in walking dysfunction, symptoms, and quality of life among Black/African Americans with MS who live in rural communities in the Southeastern US. Eligible participants must be 18-64 years old, diagnosed with MS, self-identify as Black or African American, and live in the Southeastern US. Participants will be compensated $90 for completing all study visits. Please contact Edson Flores at enrl@uic.edu or (833) 727-1887 for more information and to see if you qualify.
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Adult Volunteers ages 18-75 are needed for a study examining the relationship between oxalate handling in the blood and urine in persons with and without chronic kidney disease. The study involves consuming prepared meals over 5 days twice, one-day long visit in our clinical research unit, and the collection of urine and blood. Compensation up to $360. For more information, call 205-224-7324 or email kidneystoneresearch@uabmc.edu.
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Healthy individuals ages 18-75 are needed for a study examining the relationship between oxalate handling in the blood and urine in persons with and without chronic kidney disease. The study involves consuming prepared meals over 5 days twice, one-day long visit in our clinical research unit, and the collection of urine and blood. Compensation up to $360. For more information, call 205-224-7324 or email kidneystoneresearch@uabmc.edu.
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Help us find out by joining our study at UAB You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart or kidney problems. The study involves wearing a blood pressure monitor for 24 hours, 24-hour inpatient visits at UAB hospital, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $575 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail Nehal Vekariya at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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Do you have High Blood Pressure? Help us find out what is the right time to take blood pressure medication. You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure and have no history of heart problems or kidney problems. The study involves wearing a blood pressure monitor for 24-hours, 24-hour inpatient visits, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested.
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Do you have Type 2 Diabetes? Are you 18 years or older? Not currently taking Insulin? Are you currently being treated with stable doses of daily or weekly GLP-1 receptor agonist? This 52 week research study is seeking qualified participants to help compare the efficacy and safety of once weekly IcoSema and once weekly semaglutide. Qualified participants will receive study drug free of charge and may be compensated for time and travel. The treatment can be with or without any of the following anti-diabetic drugs with stable doses: Metformin, Sulfonylureasa , Meglitinides (glinides), DPP-4 inhibitors, Sodium-glucose co-transporter 2 inhibitors, Alpha-glucosidase-inhibitors, and Thiazolidinediones. For more information, and to see if you might be eligible to join, please contact 205-996-4015 or email at ccnrn@uab.edu.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail Nehal at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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DAY or NIGHT when is the right time to take blood pressure medication?? Help us to find out by joining our study. You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart problems or kidney problems. The study involves wearing a blood pressure monitor for 24-hours, 24-hour inpatient visits, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, wearing a blood pressure monitor for 24-hours, a 24-hour inpatient stay, and collecting blood and urine samples. The meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.

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Overweight/Obese adult volunteers needed for study If you are between the ages of 18 -89 yrs and have a body mass index > 30 kg/m2 you may be eligible to participate in a study exploring the reason why individuals who have high BMI have an increased risk of forming calcium oxalate kidney stones. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu

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Adults with Type 2 Diabetes needed for a study If you are between the ages of 18 -89 yrs and have type 2 diabetes you may be eligible to participate in a study exploring the reason why individuals who have diabetes have an increased risk of forming calcium oxalate kidney stones. Individuals who are obese, overweight, or normal weight are all welcome to the study. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information, call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu.

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