You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, have not adequately responded to at least 1 different antidepressant treatment, and are currently on an antidepressant treatment. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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Feel like you're missing out? If you are being treated for major depressive disorder (MDD) but still feel a lack or loss of interest in usually pleasurable activities, the TERPSIS Study, a clinical research study on an investigational medication for MDD, be of interest to you. The TERPSIS Study is researching a potential MDD therapy to improve symptoms of depression, and you may be eligible to participate. This study is now enrolling adults diagnosed with MDD Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no costs. Participants in the TERPSIS Study must: -Be 18 to 65 years of age -Have a clinical diagnosis of MDD -Be taking antidepressant medication(s) but still feeling a lack of interest in usually pleasurable activities -Fulfill other eligibility criteria For more information, please email kristinepike@uabmc.edu or call 205-975-8542.
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A clinical research study is now enrolling eligible adults. The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an investigational medication when it is used alone in people with TRD. You may be eligible to participate if you: • Are 18 years of age or older • Have been diagnosed with TRD • Have not adequately responded to at least 2 different antidepressant treatments If you are interested, additional eligibility criteria will be assessed by the study doctor or staff. The commitment for the study is about 24 weeks. Qualified patients may receive investigational study medication and some study-required medical care at no cost. For more information about this study, you may visit www.clinicaltrials.gov and search “54135419TRD4005” or contact Kristine at 205-975-8542 or kristinepike@uabmc.edu.

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A clinical research study is now enrolling eligible adults between the ages of 18-74 years of age. The purpose of the study is to evaluate the safety and effectiveness of an investigational medicine in people who have depression with sleep problems. Must have been diagnosed with depression, Have taken antidepressants in the past that did not work well for you and currently taking an antidepressant medication but still having symptoms of depression. Having difficulty falling asleep, or or do not feel rested the next day. If you are interested additional eligibility criterial will be assessed by the study doctor or staff. Qualified patients may receive study-related medical care and investigational study medication at no cost. In addition, reimbursement for study-related travel may be provided. Please contact Dana Green 205 975-6426

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We are enrolling opioid users without a history of psychosis, endocrine diseases, inflammatory diseases, or autoimmune diseases. If you meet these criteria you may be eligible to participate in a research study. Compensation provided up to $20. For more information, please call the UAB Office of Psychiatric Research at 205-934-8336.
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We are looking for adults between 21-55 years old and diagnosed with Attention Deficit and Hyperactivity Disorder (ADHD), and use stimulant medication to participate in our study. We want to determine the role of ADHD stimulant medication on balance and other factors, such as physical activity in improving balance performance. We hypothesize that ADHD will improve balance performance in adults with ADHD. We also hypothesize that moderate to vigorous physical activity behaviors will positively influence balance performance in this population. Participants will be required to make two visits. Once on-medication; and on the second visit, we will ask participants to forgo ADHD medication 24 hours before the testing. For more information please contact Mansour at (205) 503-2977, or by email at amansour@uab.edu.
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If you are 18 years of age or older, have tried at least 1 antidepressant medication, are feeling sad, down, hopeless, guilty, tense, or irritable, and are in good physical health, you may be eligible to participate in a research study comparing medications with transcranial magnetic stimulation. You will receive compensation for your time. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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The RECOVER study will investigate the use of Vagus Nerve Stimulation (VNS) Therapy in up to 1,000 people across the United States. To join the RECOVER study you must be 18 years or older and: currently depressed, have depression (or bipolar depression) that has lasted for at least two years or recurred several times, and have tried at least four types of antidepressant treatments and not found them helpful. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.

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You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, and have not adequately responded to at least 2 different antidepressant treatments. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have Major Depressive Disorder (MDD) that hasn’t responded to anti-depressant medication, learn about this research study of an investigational drug for MDD. As part of their study participation, patients will be regularly evaluated and closely monitored by a team of medical professionals. To pre-qualify for this study, you must: be 18 to 65 years of age; have been diagnosed with MDD; be in a current depressive episode for at least 8 weeks but not more than 12 months; and have been taking an antidepressant medication for at least the last 8 weeks. Additional criteria will apply. All study-related visits, tests, and study drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Major Depressive Disorder patients may be able to contribute to our understanding of depression. If you have Major Depressive Disorder (MDD) that hasn’t responded to anti-depressant medication, learn about this research study of an investigational drug for MDD. As part of their study participation, patients will be regularly evaluated and closely monitored by a team of medical professionals. To pre-qualify for this study, you must: be 18 to 65 years of age; have been diagnosed with MDD; be in a current depressive episode for at least 8 weeks but not more than 12 months; and have been taking an antidepressant medication for at least the last 8 weeks. Additional criteria will apply. All study-related visits, tests, and study drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you are 18 years of age or older. Have tried at least 1 antidepressant medication. Are feeling sad, down, or hopeless. Are feeling guilty, tense, or irritable, and are in good physical health. You may be eligible to participate in a research study comparing medications with transcranial magnetic stimulation. You will receive compensation for your time. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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You may be eligible to participate in a UAB research study comparing medications if you are 18 years of age or older, in good physical health, and have tried at least one antidepressant medication. You must be in a current depressive episode, feeling sad, down, hopeless, guilty, tense, or irritable.  You will receive compensation for your time. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please contact (205) 934-2484
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Have you never been diagnosed with a psychiatric condition? If so, you may be eligible to participate in a study requiring a one-time blood draw. Compensation will be provided. For more information please contact (205) 934-2484.
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Are you 19-65 years of age and in good physical health? With a good childhood, without Physical, Sexual, or Emotional Abuse? If so, you may be eligible to participate in a research study. Compensation provided up to $120. For more information, please call UAB Office of Psychiatric Research at 934-8336
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Sometimes people can experience the symptoms of depression even while on antidepressants. If you take medication for depression but have still experienced symptoms for at least 8 weeks, you may qualify for a research study testing the effectiveness of an add-on investigational therapy. Everyone qualified for this study will be seen by a doctor and receive all study-related medications, care and tests at no cost. Reimbursement for travel may be available. To learn more about this study please contact (205)-934-2484 or Sam Irvin (205)-975-6426
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Do you have Treatment-Resistant Depression? Have you tried at least one antidepressant with no relief from your depressive symptoms? Are you between the ages of 18-65? Are you interested in participating in a research study evaluating the effectiveness of a new study drug? If yes, then please call the Office of Psychiatric Research at 205-934-2484 to determine your eligibility for this study. Eligible participants will receive compensation for their time.
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Are you age 18 or older, have tried at least one antidepressant medication and feel sad, hopeless, guilty, tense or irritable and are in good physical health? You may be eligible to participate in a research study comparing medications with transcranial magnetic stimulation. You will receive compensation for your time. For more information and to determine eligibility, call Allison at 205-975-2911
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Researchers want to pay you to help us see if people can protect their mental health and their brain health. This knowledge is especially important to understand as people face difficult situations. All information collected will be kept confidential. The study involves up to 3 visits lasting 2-3 hours each, including one MRI. You will be paid for your time. For more information, please call and /or leave a voicemail at (205) 348-2808. This study is conducted under the direction of Ian M. McDonough, Ph.D.
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UAB Psychiatry is looking for participants who have never experienced trauma, abuse or neglect; have good physical health; have been diagnosed with depression or feel, sad, down or hopeless. Call 205-975-0068.

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