Bench to bedside, the Center for Clinical and Translational Science (CCTS) seeks to improve well-being and health equity in communities across the Deep South through collaborative partnerships and scientific innovation. Aligned with this mission, the CCTS Biostatistics Epidemiology and Research Design (BERD) and Informatics Initiatives seek applications proposing the development of novel statistical and computational approaches and related methodologic innovations that bridge the gap between data and clinical application.

Posted Date - May 16, 2022
Application Due Date - 5PM, June 25, 2022*
Scientific Merit Review - July 2022
Award Start Date - August 1, 2022
Award End Date - April 30, 2023
RFA Expiration Date - June 28, 2022
*Weekend applications are due the following business day: June 27, 2022 by 5PM.



  • Proposals

    Applications are invited from investigators developing novel methodology, including but not limited to statistical methods, clinical trial design, statistical genetics, approaches to the integration of quantitative and qualitative data analysis (i.e., mixed methods), clinical informatics and bioinformatics methods relevant to translational research. The methodologic developments should have the potential for implementation and application by other researchers. Priority will be given to applications that develop innovative measurement and/or analytic methods addressing health challenges pertinent to the CCTS mission.

  • Eligibility

    Full-time faculty, especially early career scholars, from any of the CCTS Partner Network institutions may apply. Trainees are encouraged to be members of the research team. More than one proposal may be submitted per faculty member serving as PI, but the faculty member is only eligible to receive one award as PI during a given funding cycle. Collaborations among CCTS Partners are encouraged, not required.

  • Funding

    Applicants may request up to $20,000 (Direct). The CCTS will support up to two (2) proposals contingent on merit, funds requested and feasibility. Indirect costs will be made available to subawarded sites.

  • Regulatory Considerations

    All regulatory approvals must be in place at the start of the award.

    Applications requiring external data that would necessitate Data Use Agreements are expected to initiate the agreements well before the proposed award date. Applicants that require IRB/IACUC approval should initiate those protocol submissions no later than June 25, 2022. Earlier submissions are advised. No Cost Extensions/Carryover will not be available.

  • Application Instructions

    Applications should be prepared as a single PDF document using 11-point Arial font, ≥ 0.5” margins and contain the following elements:

    1. Summary Page (1 page max)
      1. PI’s Name and Appointment Title
      2. Project Title
      3. If applicable, IRB or IACUC submission number and status.
      4. If applicable, Data Use Agreement number and status.
      5. Project Abstract (30 lines max)
    2. Research Plan (3 page max). Succinctly explain a problem or critical barrier to progress. Address the work, if any, has been done to address the problem. Present a research plan or solution(s) as testable hypotheses. If available, provide preliminary data. Clearly explain your research approach without using jargon. Define outcomes and the analysis plan that will be used to assess the outcomes. Address how the outcomes of the proposed work fit into a longer, larger research plan.
    3. Project Timeline (1 page max). Please address how the proposed work will be carried out August 1, 2022 through April 30, 2023. No Cost Extensions/Carryover will not be considered.
    4. Budget (1 page max). Applicants should use the PHS398 Form Page 4: Detailed Budgets for Initial Budget Period to submit their budget.
      1. Allowable costs include:
        1. Salary/Fringe: Up to 10% effort for PI (or cumulative 10% for MPIs), up to the NIH Salary Cap. Other personnel as needed to fulfill the project aims. Graduate student effort and proportional tuition according to the accounting policies of the PI’s institution.
        2. Supplies, Inpatient/Outpatient Care, and Other Expenses
      2. Unallowable costs include travel, equipment, software licenses, consultant costs, alterations, renovations and publication costs.
    5. Budget Justification (1 page max)
    6. NIH Biosketch (5 page max)

    Please submit applications by 5pm CT on the posted deadline via RED-ASSIST.

  • Review Criteria

    Awards will be scored (1-9) on aspects of significance, research team, innovation, approach and overall impact. Additional review criteria address Human Subject/Animal Protection, Budget and Timeline, and Extramural Competitiveness.

  • Award Responsibilities
    1. Award Notices - Meritorious applications will receive formal award via a Notice of Selection (NoS). Any costs incurred before receipt of the NoS are at the recipient's risk. Awards resulting from this RFA will also be subject to NIH grant terms and conditions (Award Conditions and Information for NIH Grants). Awards made to partner institutions will be amended to the existing UL1 consortium contract. No Cost Extensions (NCEs) cannot be supported through this funding mechanism.
    2. Project Action Teams - The CCTS will work with you to set up a Project Action Team. These teams will meet with you to discuss progress and help troubleshoot any barriers. This team will meet in the first week of the award period to outline all immediately urgent issues and quarterly thereafter.
    3. NIH Progress Reports - In addition to meeting with your Project Team, you will be asked to submit scientific progress reports – a template and the deadline(s) of such reports will be provided.
    4. Citing the CCTS: Anticipating the dissemination of results, publications that result from this award must include a specific acknowledgment of grant support (https://www.uab.edu/ccts/about/cite-ccts)
    5. NIH Public Access Policy – Publications resulting from this award must fulfill expectations aligned with the NIH Public Access Policy. The staff of Lister Hill Library (LHL) can help investigators navigate the Public Access Policy processes. For help, please contact Jill Deaver (This email address is being protected from spambots. You need JavaScript enabled to view it.), LHL liaison to the CCTS.

Please submit applications by 5pm CT on the posted deadline via RED-ASSIST.

Questions? General inquiries can be sent to This email address is being protected from spambots. You need JavaScript enabled to view it. or (205) 934-7442. More specific questions can be posed to:

Scientific/Research Contact, This email address is being protected from spambots. You need JavaScript enabled to view it.                               
Grants Management Contact, This email address is being protected from spambots. You need JavaScript enabled to view it.

Downloadable PDF