Case History

A 48-year-old man presents with an incidental 3 cm right adrenal mass, undergoes right adrenalectomy. The tubular and canalicular structures are positive for calretinin.

  1.        Adrenal cortical adenoma
  2.        Metastatic signet ring cell carcinoma
  3.        Adenomatoid tumor
  4. Composite adrenal cortical adenoma and adenomatoid tumor

 collsion tumor collsion tumor.tif 2

Case History

A 7 y/o M with pancytopenia and splenomegaly. Which one of the following is NOT included in DDx:

  1.        Gaucher disease.
  2.        MAC infection.
  3.        Mast cell disorder
  4. Whipple disease

Question Photo 15.2.22 Case 2
Question Photo 3 pic4

Case History

The patient is a 35-year-old-female with leukocytosis. Peripheral blood findings showed increased blasts consistent with acute leukemia. The morphology is suggestive of which genetic abnormality?

A. RUNX1-RUNX1T1
B. MLLT3-MLL
C. PML-RARA
D. CBFB-MYH11

Question Photo 15.2.22 Case 2Question Photo 3Question Photo 4

Case History

A 48-year-old woman underwent a hysterectomy for a uterine mass. The neoplastic cells stained positive for CD10, ER, SMA, focal cyclin D1, and negative for desmin, caldesmon, STST6, SF1, and HMB-45. Sarcoma fusion panel showed JAZF1-SUZ12 fusion.

What is the correct diagnosis?

A. High-grade endometrial stromal sarcoma
B. Endometrial stromal nodule
C. Low-grade endometrial stromal sarcoma
D. Smooth muscle tumor of uncertain malignant potential (STUMP)

 5.2.22 Case 1 Photo

Case History

22-year-old female with hilar and mediastinal lymphadenopathy, FNA of mediastinal lymph node.

What stains would you order to further work up the case?

A. Pax-8, WT-1
B. CD15, CD30
C. CK7, CK20
D. Gata-3, Mammaglobin

  Herndon22Case1

Case History

This is a fine needle aspiration of a 4.1 cm indeterminate soft tissue mass in the pancreatic head of a 41-year-old male.

What is the most likely diagnosis?

A. Leiomyosarcoma
B. Neurofibroma
C. GIST
D. Fibromyxoid sarcoma

 Atif2022Case1 Atif2022Case2

Case History

30-year-old presenting with bilateral papilledema and vision problems. Neuroimaging reveals a 2.7 x 2.1 cm right cerebellar mass

What is the most likely diagnosis?

A. Metastatic Renal Cell Carcinoma
B. Melanoma
C. Hemangioblastoma
D. Angiosarcoma

Williams22CasePic1 Williams22CasePic2

Case History

39-year-old female, endometrial biopsy

What is the most likely diagnosis?

A. Uterine tumor resembling ovarian sex cord tumor
B. Endometrial stromal nodule with sex cord-like differentiation
C. Highly cellular leiomyoma
D. Endometrial polyp

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Case History

A 16-year old female presents with abnormal uterine bleeding. A 3.5 cm submucosal leiomyoma is clinically suspected, and she underwent a hysteroscopic myomectomy. 

What is the most likely diagnosis?

A. Müllerian adenosarcoma
B. Atypical polyploid adenoma
C. Benign adenomyomatous polyp
D. Benign endometrial polyp

  PesoliCase1 PesoliCase2