Are you an adult above 18 years of age with high blood pressure?

You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, wearing a blood pressure monitor for 24-hours, a 24-hour inpatient stay, and collecting blood and urine samples. The meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.