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The Blazer Bridge Fund is intended to identify and assist in the development of promising ideas, discoveries, innovations and/or technologies from UAB faculty and staff that have commercial potential.
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UAB researchers conducted a study in end-stage heart failure patients with cardiogenic shock that revealed that B-type natriuretic peptide levels were elevated in end-stage heart failure but did not predict clinical outcomes.
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Lung-resident memory B cells produced during influenza are long-living immune cells that migrate to the lungs from draining lymph nodes and lie in wait as early responders that can quickly react to future infections. They are key sentinels against subsequent viral variants.
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The M.D./Ph.D. student has since moved on to clinical studies, but the research into possible drugs to treat Alzheimer’s disease continues.
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The modified mRNA — delivered after experimental heart attacks — transiently allows heart muscle cells to proliferate, leading to reduced infarct size and improved heart performance compared to untreated animals.
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While preventive treatment with vigabatrin delayed the onset and prevalence of infantile spasms in TSC infants, it had no impact on focal seizures, drug-resistant epilepsy, or improvement of cognitive and behavioral scores at 24 months.
