Department Welcomes Vitturi Back to UAB as Assistant Professor
Written by Christina Crowe
The Department of Pathology is excited to welcome Dario Vitturi, Ph.D., back to UAB as assistant professor, Molecular and Cellular Pathology.
Originally from Montevideo, Uruguay, Vitturi obtained his Ph.D. at the University of Alabama at Birmingham under the direction of Rakesh Patel, Ph.D., Vice Chair, Research, in the Molecular and Cellular Pathology graduate program. Upon completion of his graduate studies, Vitturi joined the Department of Pharmacology and Chemical Biology at the University of Pittsburgh, first as a postdoctoral associate under the direction of Dr. Bruce Freeman, and then as a faculty member.
Read moreWilliams Named to The Pathologist's Power List for 2022
Written by Christina Crowe
Michael Williams, M.D., M.Sc., Neuropathology fellow with UAB Pathology, has been selected as an honoree for The Pathologist's 2022 Power List, in the category of "First Contact." The list, published by the magazine, is an annual celebration of the great and inspirational minds that underpin the medical laboratory and honors select individuals in six different categories.
Williams was honored in the "First Contact" category, recognizing his work on the podcast he hosts, "Diversity in Path," which aims to, "explore how investing in diversity can lead to a high return of investment in pathology and lab medicine by learning from the knowledge and experiences of diverse voices within in our field."
Williams started the podcast in August 2021 shortly after moving to Birmingham to start his two-year Neuropathology fellowship at UAB Pathology. In each episode, he interviews individuals in the field.
Read moreLeal Receives ALA Award to Study COVID-Associated Mold Infections
Written by Christina Crowe
Sixto Leal, M.D., Ph.D., Assistant Professor and Associate Director, Division of Laboratory Medicine, was recently awarded an American Lung Association COVID-19 Respiratory Virus Research Award for his project, “The Impact of SARS-CoV-2 Immune Dysregulation on Antifungal Immunity.” This is a two-year, $200,000 award.
The aim of the study is to evaluate whether immune responses targeting intracellular viruses (viruses that live inside host cells) compromise the ability of the immune system to simultaneously control mold infection.
“Unlike most invasive mold infections, COVID Associated Pulmonary Aspergillosis (CAPA) occurs in individuals with otherwise intact immune systems. This suggests the presence of novel biological mechanism/s rendering individuals susceptible to invasive fungal infection,” Leal says.
Read moreReddy Receives Honor of President's Award for Excellence in Teaching
Written by Christina Crowe
The Department of Pathology is pleased to announce Vishnu B. Reddy, M.D., as this year’s recipient of the 2022 President’s Award for Excellence in Teaching in the Heersink School of Medicine – Joint Health Science.
Begun in 1990 by former UAB President Charles McCallum, the award recognizes full-time regular faculty members at UAB who have demonstrated exceptional accomplishments in teaching, with a recipient from each of the schools and the Joint Health Sciences.
“Teaching for me always a self-learning process, and the most challenging aspect is conveying that passion to attendees,” Reddy says, “but in practice, it is more like ‘Nishkam Karma’ in Sanskrit, meaning action without motive or expectation.”
Read moreMiller Named Co-Director of UAB Neuroscience Theme
Written by Hannah Buckelew
C. Ryan Miller, M.D., Ph.D., Vishnu B. Reddy Translational Research Endowed Professor and Division Director, Neuropathology, has been named co-director of the Graduate Biomedical Sciences (GBS) Neuroscience Theme (NEURO).
Read moreLin Named a CAP State Commissioner
Written by Hannah Buckelew
Diana Lin, M.D., an assistant professor in the Division of Anatomic Pathology, has been approved as an Alabama State Commissioner and Division Commissioner for the Florida Panhandle for the College of American Pathologists (CAP) Accreditation Program, effective immediately.
The CAP is a leading organization of board-certified pathologists with a goal to foster excellence in laboratories and advance the practice of pathology and laboratory medicine. Founded in 1946, the organization now boasts approximately 18,000 pathologists.
Read moreWHO Classification of Tumours Publishes 5th Edition, Volume 8: Urinary and Male Genital Tumours
Written by Christina Crowe
The World Health Organization, in its seminal series on the classification of tumors, recently published, "WHO Classification of Tumours, 5th Edition, Volume 8: Urinary and Male Genital Tumours," with George Netto, M.D., Robert and Ruth Anderson Endowed Chair, as an expert member of the urinary and male genital tumors editorial board. It is now available in print and digital formats.
The WHO Classification of Tumours Editorial Board convened via video conference January 18-20, 2021, to complete the editorial work in the book.
"It is my distinct pleasure to serve on this editorial board, and contribute to this seminal volume in our field," Netto says.
Read moreResearch Dialogue: Dr. Vivek Nanda
Vivek Nanda, Ph.D., an assistant professor in the Division of Molecular and Cellular Pathology (MCP), is an active researcher in the UAB Department of Pathology. Dr. Nanda joined UAB in January 2020 from Stanford University in California where he was an instructor. Nanda earned his M.S. and Ph.D. in Pharmacology from the University of Rochester in New York. In an effort to showcase the impactful contributions of UAB Pathology researchers, Nanda answers some questions about his areas of research and what led him to UAB.
What is your research focus?
My lab focuses on identifying the heritable component of a wide range of cardiovascular disease including atherosclerosis, abdominal aortic aneurysm and peripheral artery disease. To this end, we utilize publicly available genome-wide genetic and bioinformatics resources in combination with in vitro and in vivo approaches to discover the implicated gene and associated signaling pathway.
Read moreUAB Department of Pathology Establishes Division of Women’s Health
Written by Christina Crowe
The University of Alabama at Birmingham Department of Pathology has established its new Division of Women’s Health.
The UA Board of Trustees approved the division in February 2022. Interim Division Director Thomas Winokur, M.D., will lead the division as an ongoing recruiting effort for a permanent director takes place. Winokur says the creation of the division stands to help emphasize our departmental and institutional commitment to women’s health.
“The establishment of this division serves to unify the subspecialties we have focused on in women’s health in pathology as a field--obstetrics/gynecology, breast, perinatal—and bring them under one umbrella,” Winokur says.
Read moreResearch Dialogue: Dr. Eason Hildreth
Eason Hildreth, D.V.M., Ph.D., an assistant professor in the Division of Molecular and Cellular Pathology (MCP), is an active researcher in the UAB Department of Pathology. Dr. Hildreth joined UAB in July 2019 from the Medical College of South Carolina and has since shown his dedication to the field and the Department. In 2021, he received a two-year Early Career Investigator grant from METAvivor Research and Support for his research on breast cancer and was also named a UAB Heersink Pittman Scholar. In an effort to showcase the impactful contributions of UAB Pathology researchers, Hildreth answers some questions about his areas of research and what led him to UAB.
What is your research focus?
We are interested in genetic programs in the tumor microenvironment that drive cancer progression. To date, this has largely hinged on genetically (using genetically-modified mice) and therapeutically (using microparticle drug delivery) targeting tumor-associated macrophages independent of where the tumor is located and targeting osteoclasts in bone metastasis in breast cancer. More recently, this has expanded to an interest in cancer-associated fibroblasts and renal cancer (another bone metastatic malignancy).
Read moreThree New Faculty Join Division of Laboratory Medicine in July
Written by Hannah Buckelew
On July 1, 2022, the Department of Pathology welcomes three new faculty members to the Division of Laboratory Medicine, directed by Vishnu Reddy, M.D.
Megan Amerson-Brown, Ph.D., CIC, MLS, joins the department as Assistant Professor from the Baylor College of Medicine, where she recently completed a Medical and Public Health Microbiology fellowship.
Amerson-Brown received her Ph.D. in Human Pathophysiology and Translational Medicine in 2019 from the University of Texas Medical Branch (UTMB) Graduate School of Biomedical Sciences before working as an Infection Control Consultant in response to COVID-19 with Hospital Executive Interim Management and Consulting at Elmhurst Hospital in Queens, New York. She has served as a Graduate Research Assistant at UTMB Galveston and as adjunct faculty, infection preventionist, and medical technologist in Microbiology at MD Anderson School of Health Professions and Cancer Center.
Read moreUAB Pathology Researcher Named 2022 O’Neal NextGen Scholar
2022 O’Neal NextGen Scholar predoctoral award.
Amr Elhamamsy, a cancer biology theme student in the laboratory of Rajeev Samant, Ph.D., Professor, Molecular and Cellular Pathology, is the recipient of a Read moreFirst Education Retreat a Swimming Success
Written by Christina Crowe
On Saturday, June 18, the UAB Department of Pathology sponsored an inaugural departmental Education Retreat at Camp Fletcher in McCalla, Alabama. This casual, fun event welcomed trainees, faculty and staff to mingle and enjoy recreational activities in a low-key, outdoor setting.
Amid a heat wave, the weather cooperated, and participants enjoyed the pool as an escape from the sun. Under a covered pavilion, fans cooled those who chose to hang out and play games. The camp setting offered activities for everyone, including hiking, canoeing, and corn hole. A few individuals brought their own yard games, such as jumbo Jenga, kickball, and disc golf. Traditional and alternative options in a burger bar provided by Front Porch kept everyone fed and well hydrated in the summer weather.
Read moreFormer Resident Brossette Establishes Endowed Support Fund
Written by Christina Crowe
The Department of Pathology is pleased to announce the establishment of the Stephen E. Brossette, M.D., Ph.D., Endowed Residency Program Support Fund, effective April 2022.
The fund includes an annual award, administrated by the department, with any additional funds used for professional development, travel, or other support for the residency program. Each year, the department will administer the PEARL Award to the pathology resident who demonstrates excellence in Patient care, Education, and Research within Laboratory medicine (or just ‘the Lab’). The candidate will be selected by vote among laboratory medicine (and affiliated divisions) as well as hospital laboratory supervisors, who interact with residents regularly. The criteria include demonstrating initiative, effective communication, collaboration and teamwork, patient care, research, and innovation/quality focus.
Read moreThree Faculty Named or Elevated to Newly Endowed Positions
Written by Christina Crowe
The Department of Pathology is excited to announce three endowment updates for our faculty:
The endowment held by Yabing Chen, Ph.D., Vice Chair for Faculty Development and Education—a professorship—has been elevated to and is fully endowed as a chair. Dr. Chen is now the Jay M. McDonald Endowed Chair in Laboratory Medicine. The department is grateful for the ongoing support of former chair Jay M. McDonald, M.D., Ph.D., and his wife, Sarah, with the generous funding of this endowment.
Shu Chen, Ph.D., Professor, Neuropathology, is named the inaugural holder of the Ona Faye-Petersen Endowed Professorship, established in 2021, supported by the department. Dr. Chen joined the department in December 2021 from Case Western Reserve University’s Department of Pathology.
UAB Pathology Fellow Featured in ASCP's Pride in the Laboratory
Written by Hannah Buckelew
Michael Williams, M.D., M.S.c., Neuropathology Fellow in the UAB Department of Pathology, was featured in the American Society for Clinical Pathology's (ASCP) Critical Values magazine PRIDE in the Laboratory campaign on June 14, for his personal essay, titled, "Is there even a guidebook?"
Read moreProteomic study of 2,002 tumors identifies 11 pan-cancer molecular subtypes across 14 types of cancer
by Jeff Hansen
A new study that analyzed protein levels in 2,002 primary tumors from 14 tissue-based cancer types identified 11 distinct molecular subtypes, providing systematic knowledge that greatly expands a searchable online database that has become a go-to platform for cancer data analysis by users worldwide.
Read moreAl Diffalha, Stanek's Art Featured in The Pathologist
Sameer Al Diffalha, M.D., Associate Professor, Division of Anatomic Pathology, and Caroline Stanek, M.D., PGY1, were featured in The Pathologist magazine’s “The Art of Pathology” series for their artistic microscopic image submissions.
The series is featured online and in print to immerse readers in the "...beauty behind the slides.”
Read moreUAB Celebrates Weaver's NAS Election
Written by Christina Crowe
On Monday, May 23, leadership from across the UAB campus came together to celebrate the election of Casey Weaver, M.D., the Wyatt and Susan Haskell Endowed Chair for Medical Excellence for his recent election to the National Academy of Sciences.
At an event held at the UAB Hilton, Ray Watts, M.D., UAB President, joined Selwyn M. Vickers, M.D., FACS, dean of the UAB Heersink School of Medicine, CEO of the UAB Health System and CEO of the UAB/Ascension St. Vincent’s Alliance and others to congratulate Dr. Weaver and recognize him for 30 years of research and clinical work at UAB.
Read moreVarambally's Latest Cancer Research Featured in Nature Communications
Written by Christina Crowe
Sooryanarayana Varambally, Ph.D., Professor, Molecular & Cellular Pathology, Director, Translational Oncologic Pathology Research, and his research team recently published an article in the journal Nature Communication featuring work they shared on their cancer data tool, UALCAN, "Proteogenomic characterization of 2002 human cancers reveals pan-cancer molecular subtypes and associated pathways." https://www.nature.com/articles/s41467-022-30342-3
UALCAN stands for University of Alabama Cancer Database, and is designed as an easy-to-use, interactive web portal to perform to in-depth analyses of TCGA gene expression data.
Following, Dr. Varambally explains the research highlighted in the article:
"In the current study published in Nature Communication, we systematically assessed pathway-level somatic alterations (by small mutation or copy number alteration) across tumors. In this study, along with our collaborator Dr. Chad Creighton from Baylor College of Medicine, lead author, we assembled a compendium dataset of mass-spectrometry-based proteomics data from 2002 primary tumors from 14 cancer types and 17 studies. We integrated proteomic data with other omics data to examine how somatic mutation affecting a given pathway shows up at the protein level. Further, the data were provided in UALCAN for cancer researchers and clinicians across the world."
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