Clinical Trials

Participate in nationwide study to understand why some people have prolonged symptoms (referred to as long COVID or post-acute sequelae of SARS-CoV-2, also called PASC) or develop new or returning symptoms after the acute phase of SARS-CoV-2 infection. We need COVID-19 survivors from the Birmingham and Mobile, Alabama, and New Orleans, Louisiana, areas. If you are over 18 years old, not pregnant, and would like to take part in UAB’s study, email COVIDResearch@uabmc.edu to find out more.
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August 08, 2022

Obese Adults Needed

Obese adults, age 25 to 45 years old, are needed to determine if the timing of salt intake affects blood pressure throughout the day. This study involves 12 visits over 8 weeks. Participants will be compensated for participation. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please contact Alexis at aelambert@uabmc.edu or call (205) 582-7761 if you are interested in learning more about this study.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, in collaboration with Novo Nordisk, is conducting a 52 week research study to look into how well semaglutide once weekly medicine works at different doses in people with type 2 diabetes and overweight Qualified participants will receive study drug free of charge and may be compensated for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage? To find out if you are eligible, please call at 205-934-1777 or email Dr. Russell Stanley at russellstanley@uabmc.edu. $200 Compensation will be provided.
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Do you have infrequent or irregular cycles? or Do you have excessive hair growth on your upper lip, chin, chest, abdomen, buttocks, or back? If you are between 18 and 35 years old, and answered YES to any of the questions above you may qualify for this study. Benefits: Free physical exam, labs and ovarian imaging, Receive up to $600 for complete participation in the study. Help to improve our understanding of women's health. For More information Please call (205) 934-0877 or email slangan@uabmc.edu
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Has your child been diagnosed with non-alcoholic fatty liver disease (NAFLD) or elevated liver enzymes? If so, he/she could be eligible to participate in a 6-month research study that is investigating whether changes in diet composition affect various health outcomes in adolescents with non-alcoholic fatty liver disease. You will receive diet counseling and groceries at no cost. Participants will be compensated up to $1475 if completed the study. For more information or to enroll in our study, please email alexlm@uabmc.edu or call 205-934-6299. Participants cannot be claustrophobic.
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If you are 19 or older and an exclusive vaper (meaning only vaping and no cigarette smoking) who lives with someone that does not vape, or a non-vaper who lives with an exclusive vaper, then you may qualify for this study. The person who vapes/does not vape can be your roommate, partner etc. Potential participants will be screened prior to enrollment to ensure they are eligible. Once enrolled, participants will blow into a spirometer, which will measure their lung function and answer questions on respiratory symptoms. If you are interested, please email at rvlab1665@gmail.com or provide your details via this link: https://uab.co1.qualtrics.com/jfe/form/SV_6ExuSQMcdg3AC8K and we will contact you. Thank you!
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Recovering from a stroke? Still have problems with confusion, slow thinking, or memory? If so, you may eligible to take part in a study testing a new form of cognitive training designed to improve how quickly you process information and perform daily activities. The study pays participants $20 per training session on average. The training program, which requires several visits to UAB, can be tailored to fit your schedule. If you are interested, please call 205-934-9768 or email stacemc@uab.edu
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You may be eligible to participate in a research study about the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to blood pressure. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated $575 for completing all the visits. To participate, please contact Haley at 205-975-5825 or email us at nauticalstudy@uabmc.edu.
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Eligible participants must be healthy adults (BMI less than 45 kg/m2) and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, performing exercise on a treadmill, undergoing a glucose test, and collecting blood, urine samples, and collection of genetic information. Participants will be compensated $300 for completing all the visits and meals will be provided at no cost. Please e-mail us at, genesis@uabmc.edu or call us at (205) 975-3956 if you are interested.
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We are looking for male or female adults (18-65) who have had an amputation at least 6 months ago. This study is designed in two Phases to assess the needs of the local amputee population and to determine the potential of a diet to reduce pain and increase quality of life in amputees. In Phase 1, eligible participants will be asked to complete a small packet of questionnaires examining quality of life and diet. In Phase 2, eligible participants with pain for at least 6 months will complete a week of baseline diet and pain data collection before being placed on a 6-week low-carbohydrate diet. During the diet intervention, daily food will be provided and participants will return for testing at 3 and 6 weeks. Participants will receive up to $50 for completing Phase 1 and $150 for completing Phase 2 of the study. You may not be eligible to participate if you have significant health problems, or are taking certain medications. Please contact parade.study@gmail.com or call 205-234-1201. Leave a short message with your name, number, and mention that you are interested in the PARADE study.
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You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, have not adequately responded to at least 1 different antidepressant treatment, and are currently on an antidepressant treatment. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.
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If you’re being treated for MDD and your current antidepressant medication(s) is not working, the SAVITRI Study might interest you. The SAVITRI Study is researching a potential MDD therapy to improve symptoms of depression, and you may be able to participate. This research study is now enrolling adults diagnosed with MDD. Those who qualify will receive the investigational medication (or placebo), study-specific medical exams, and study-specific laboratory tests at no cost. Participants in the SAVITRI Study must: be 18 to 65 years of age; have a clinical diagnosis of MDD; be currently on antidepressant medication(s); have had inadequate response to up to 5 oral antidepressant medications; and fulfill other eligibility criteria. For more information, please call (205) 996-5987 or email lalexander@uabmc.edu. Please mention SAVITRI in your message.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail Nehal Vekariya at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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The Alabama Vaccine Research Clinic is conducting a COVID-19 Vaccine Research Trial Located at UAB’s 1917 Clinic at Dewberry on 5th Ave, the Alabama Vaccine Research Clinic is studying novel COVID-19 vaccines and how they can offer a broader range of protection against new variants. To qualify for this study you must be a generally healthy adult, 18 years or older, and have received a FULL series of COVID-19 Vaccination and a booster vaccination. Participation in this study will include 8-13 clinic visits. Study participants will receive COVID-19 variant vaccines. Compensation will be provided. If you are interested in participating in this study trial, or want more information on the Alabama Vaccine Research Clinic, please visit us at https://sites.uab.edu/avrc
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Do you have High Blood Pressure? Help us find out what is the right time to take blood pressure medication. You may be eligible to participate in the PRECISION-BP research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure and have no history of heart problems or kidney problems. The study involves wearing a blood pressure monitor for 24-hours, 24-hour inpatient visits, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu or call us at 205-934-7173 if you are interested.
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Healthy volunteers between the ages of 14 and 45 needed for research on psychosis spectrum disorders. Study procedures include: three MRI scan visits and two office visits over the course of 16 weeks, a clinical interview, memory, thinking, and concentration evaluations, and optional blood draws. Each of the five study visits will take approximately 3 hours. Compensation is up to $530. If interested please contact a member of our research staff at (205) 996-9813.
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Healthy volunteers between the ages of 19 and 45 needed for an MRI research study. Study procedures include a clinical interview, a one hour MRI scan, and a 30 minutes MRI scan. Compensation up to $110. If you are interested please call a member of our research staff at (205) 996-9813.
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Are you currently pregnant? If you are 14 to 39 years of age, less than 18 weeks pregnant, and planning to deliver at UAB, you may be eligible for our education based study. This study focuses on learning about healthy behaviors and how to make positive changes that could lead to a healthier pregnancy for both you and your baby. There are four study visits spread out over 13 weeks during pregnancy and one brief post-delivery visit where study staff visit participants in the post-partum unit. Participation includes a one-on-one education session, answering several questionnaires, and collecting lab work, including blood, mouth swabs & self-collected urine samples, and vaginal swabs. Also, three times during the study, participants are given a packet to collect two swabs at home and mail them in. Participants are compensated $230 for completing all study visits and specimens. For more information, please call Leslie Black at 205-919-5945, email PrPrepStudy@uabmc.edu, or text 408-214-0980.
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Researchers in the UAB School of Medicine are recruiting individuals 18 years and older who have drank alcohol in the past year. The study involves completing a brief online screening questionnaire to determine your eligibility. If you are eligible, you will complete a second set of questionnaires that lasts 90 minutes for which will receive $30. For more information about our study, please email us at trustlab@uabmc.edu
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You may be eligible to participate in a research study: If you are a healthy female, between age of 18-50, still having a regular menstrual cycle & you are NOT on hormonal birth control (birth control pills or shots (i.e. Depo shot) or IUD, like Mirena). And, if you are willing to undergo an endometrial biopsy procedure. Participants will be compensated total of $200. Only requires 2 visits. For information, call us at 205-934-5498 or email Stephanie Clevenger at slangan@uabmc.edu.
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Do you have pain in one or both of your knees on most days? If so, you may qualify for a research study being conducted at the University of Alabama Birmingham. We are seeking people between 45 and 85 years of age to participate in a study of brain and breathing treatments for arthritis pain. The study involves seven visits over a three-week period to the study center at the University of Alabama Birmingham, where clinical tests and brain stimulation treatment will be done, along with brain scanning. Participants will receive $350 for completing the study. If you are interested, please call the PROACT Study at 205-934-9614.
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We are looking for individuals with spinal cord injury to participate in a home based exercise program for improving cardiometabolic health outcomes, such as body weight, blood sugar, cholesterol, and cardiovascular fitness. To qualify you must have a confirmed diagnosis of SCI at the cervical or thoracic level (C7-T12, classified as A, B, C, or D on the AIS scale), be at least 3 years post-injury, aged 19-65 years old. Participants will exercise for 16-weeks from home using an arm crank cycle ergometer and will receive $300 for completing the study. For more information, and to see if you might be eligible to join, please contact (205) 996-4114 or email at grdnfs@uab.edu

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This study is looking for individuals with spinal cord injury to participate in a home based exercise program for improving cardiometabolic health outcomes. Qualified participants must be at least 3 years post-injury, between the ages of 19-65, and must have a confirmed diagnosis of SCI at the cervical or thoracic level (C7-T12, classified as A, B, C, or D on the AIS scale). Participants will exercise for 16-weeks from home using an arm crank cycle ergometer. Participants will be compensated $300 for completing the study. For more information, and to see if you might be eligible to join, please contact 205-996-4114 or email at grdnfs@uab.edu.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated $350 for completing the study visits. Please e-mail Nehal at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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DAY or NIGHT when is the right time to take blood pressure medication?? Help us to find out by joining our study. You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women, have high blood pressure, and have no history of heart problems or kidney problems. The study involves wearing a blood pressure monitor for 24-hours, 24-hour inpatient visits, taking medications, and collecting blood and urine samples. Meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.
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Women 18 years and older who are currently experiencing any vaginal symptoms are invited to participate in a research study evaluation a new diagnostic test for bacterial vaginosis and vaginal yeast infection. Please call the UAB Sexual Health Research Clinic at 205-934-8166. Compensation will be provided.
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Minimum Eligibility Requirements: • You are 18- to 35-years-old. • You are currently wearing glasses/contact lenses. • You know how to use soft contact lenses. • You have had an eye exam within the last 2 years This study includes four to six visits, which will happen over ten weeks. If eligible, you will be compensated $20 to $40/visit with a maximum of $140 for your participation in the study. If interested, please contact Keyur Savla at 205-212-0355 or ksavla@uab.edu for additional information.

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Do you have Urinary Leakage? If you are eligible (women 65 years or older), you will take part in a 12-week hip muscle exercise program, individualized sessions taught by a licensed physical therapist specialized in hip strength. The program offers 12 private sessions, alternating in-person and phone visits (a “home program”) Compensation will be provided. For more information, please call 205.934.5498.

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Participants must be: • Ages 21 to 65 • Able to safely consume alcohol • In good physical and mental health Participant activities: Attend an initial 1-hour study appointment, and a second appointment lasting 1-11.5 hours. Incentives: $20 for Session 1. For Session 2, earn $20 per hour, between $20 and $200. Alcohol and Mood Study: trustlab@Uabmc.ed; 205-975-9943 / 205-977-8948
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We are recruiting 9th grade Black males for a new study that is focusing on film viewing and academic functioning. The project involves viewing 4 films and completing 3 surveys with the ability to make up to $70 dollars for participating. This study is designed to take place completely from the participant’s home. If you are interested in learning more email afis.uab@gmail.com or call/text at (205) 549-3416 for more information.
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan or Valsartan on your body’s 24-hour rhythm of a hormone in your blood called natriuretic peptides. This hormone and the study medications are related to the heart. Eligible participants must be obese (BMI: 30-45 kg/m2) men and women and have no history of diabetes, heart problems, or kidney problems. The study involves consuming prepared meals, wearing a blood pressure monitor for 24-hours, a 24-hour inpatient stay, and collecting blood and urine samples. The meals will be provided at no cost. Participants will be compensated $560 for completing the study visits. Please e-mail Nehal at PRECISION-BPSTUDY@uabmc.edu if you are interested.

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Overweight/Obese adult volunteers needed for study If you are between the ages of 18 -89 yrs and have a body mass index > 30 kg/m2 you may be eligible to participate in a study exploring the reason why individuals who have high BMI have an increased risk of forming calcium oxalate kidney stones. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu

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Adults with Type 2 Diabetes needed for a study If you are between the ages of 18 -89 yrs and have type 2 diabetes you may be eligible to participate in a study exploring the reason why individuals who have diabetes have an increased risk of forming calcium oxalate kidney stones. Individuals who are obese, overweight, or normal weight are all welcome to the study. Participation involves eating study-provided meals for 4 days, providing urine and blood samples. Study meals are provided free of charge and additional compensation up to $140 is offered. For more information, call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu.

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Do you experience urine leakage with a strong and sudden urge and you leak before reaching the toilet? You may be eligible to participate in this important study if you are female and 21 years of age or older, if you are experiencing urine leakage with the feeling of urgency, coughing, sneezing, or laughing. For more information, contact our research team at 205-934-5498. Compensation is provided.

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Do you experience accidental bowel leakage? You may qualify for a bowel leakage research study if you are female, 18 years or older, and have had accidental bowel leakage for at least 6 months. For more information contact 205-934-5498. Compensation is provided.

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You may be eligible to participate in the UAB’s Cardiovascular Research Biobank (CARBON), a repository of biological samples that will be used for future research about heart disease, diabetes, genomics, and more. Participants must be over the age of 18. The study will require one brief visit to UAB and collection of blood samples. Participants will be compensated. Please contact Nehal Vekariya at carbonstudy@uabmc.edu or 205-934-7173 if you are interested.

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Healthy Volunteers Needed If you are: • 18-50 years of age • Can read and write in English • Are generally healthy • And have no history of mental illness or psychiatric disorders

For more information and to determine eligibility, please call UAB Office of Psychiatric Research at (205) 934-8203. **Compensation is provided**

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The UAB Epilepsy Center is looking for participants aged 15 and older for a brain imaging study. Eligible individuals will have psychogenic non-epileptic seizures (PNES) without co-morbid epilepsy. The study involves one visit at UAB Highlands Hospital and will last up to 2.5 hours. Participants will undergo a brain MRI, complete questionnaires, and provide a small amount of blood. You will be compensated $100 for completing the visit. If interested, please contact Dr. Christina Mueller at (205) 671-4355 or cm1@uab.edu.

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Do you have pain in one or both of your knees on most days? If so, you may qualify for a research study being conducted at the University of Alabama Birmingham. We are seeking people between 45 and 85 years of age to participate in a study of brain and breathing treatments for arthritis pain. The study involves seven visits over a three-week period to the study center at the University of Alabama Birmingham, where clinical tests and brain stimulation treatment will be done, along with brain scanning. Participants will receive $350 for completing the study. If you are interested, please call the PROACT Study at 205-934-9614.

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Are you a Female and Experience a Loss of Urine with Urge and Frequency? Do you have Overactive Bladder with Urinary Leakage? Compensation will be provided. To find out if you are eligible, please call at 205-934-1777 or email Dr. Russell Stanley at russellstanley@uabmc.edu.

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Are you struggling with Opioid addiction? If so, you may be eligible to participate in a research study at UAB that focuses on biomarkers in people with opioid addiction. The study includes 1 visit and takes up to 2 hours to complete. For more information, please call the UAB Office of Psychiatric Research at (205) 934-8336. You will be compensated $20 for your time and efforts.
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Healthy women needed for a research study. You may be eligible to participate in a research study: If you are female between age of 18-45, If you a healthy and still having a regular menstrual cycle, And, if you are willing to undergo an endometrial biopsy procedure. Participants will be compensated total of $200. Only requires 2 visits. For information, call us at 205-934-5498 or email Stephanie Clevenger at slangan@uabmc.edu.
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Are you 18 years old or older? Have you drank alcohol in the past year? Researchers in the UAB School of Medicine are recruiting individuals 18 years and older who have drank alcohol in the past year. The study involves completing a brief online screening questionnaire to determine your eligibility. If you are eligible, you will complete a second set of questionnaires that lasts 90 minutes for which will receive $30. For more information about our study, email us at arshnoorgrewal@uabmc.edu.
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You may be eligible to take part in this study if you have previously had a heart attack (myocardial infarction) or brain attack (stroke) or have been diagnosed with poor circulation. If you have reduced kidney function or if you have inflammation in your blood vessels ? The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 4 year research study to look if an investigational medicine ,called ‘ziltivekimab’ can be used to treat people with cardiovascular disease, chronic kidney disease and inflammation. Qualified participants will receive study drug at no cost and may be compensated for time and travel. For more information, and to see if you might be eligible to join, contact (205) 996-4015 or email at ccnrn@uab.edu.
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You may be eligible to participate in a research study about the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated. To participate, please contact Nehal at 205-934-7173 or email us at nauticalstudy@uabmc.edu.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians, and have no history of diabetes, heart problems, or kidney problems. The study involves performing the exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Nehal Vekariya at exercisebetastudy@uabmc.edu or call us at 205-934-7173 if you are interested.
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Clinical trial evaluating a novel, non-invasive radiation treatment for ventricular tachycardia refractory to medication and catheter ablation The UAB Departments of Radiation Oncology and Cardiology are looking for patients with ventricular tachycardia (VT) not controlled by medications and catheter ablation. The trial will allow patients suffering from VT despite standard of care regimens to undergo non-invasive cardiac radioablation (CRA; a type of stereotactic body radiotherapy) to the area of the heart responsible for their symptoms. Stereotactic body radiotherapy is delivered with a device called the linear accelerator, which is primarily used to treat patients with cancer. UAB is one of the first centers in the U.S. to obtain a Food and Drug Administration (FDA) investigational device exemption for use of the linear accelerator in this capacity on a phase I/II trial. The study is being conducted in collaboration with the Washington University School of Medicine in St. Louis, a center which pioneered this promising technique in the U.S. For more information on the RAD 1901 trial, please contact Adelyn Gillon, clinical research coordinator, at 205.975.3019 or agillon@uabmc.edu" contenteditable="false">agillon@uabmc.edu.
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November 23, 2021

Asthma clinical trial

If you have asthma, are at least 18 years of age, in the Los Angeles Region, (California) haven’t had oral steroids in at least 4 weeks, and are willing to donate 30 mL of blood, equivalent to two tablespoons, please contact Racheal Ogbebor at email Rachealogbebor@gmail.com.
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Rural Research Participants Needed FSU College of Nursing invites individuals with heart failure and their care partners who live in rural areas to participate in a research project under the direction of Lucinda J. Graven, Ph.D., APRN. Care teams will partner with a registered nurse to manage daily challenges related to heart failure self-care by telephone. Compensation up to $200 per care team who complete the telehealth program. Please contact Joan Grant Keltner, Ph.D., RN at (205) 934-6527 or grantj@uab.edu. For more information, you may also use: https://fsu.qualtrics.com/jfe/form/SV_3IPqQs7MAPmuHpH.
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Participants between the ages of 65-89, and individuals diagnosed with Parkinson’s disease between the ages of 45-89 are needed for a research study on walking. This study is being done to assess how well individuals can modify walking patterns. If you qualify, we anticipate that your participation in the study will span a single study visit, with a total time commitment of 3 hours. You will be compensated for your time. Contact Christopher Hurt at cphurt@uab.edu or  at 205-934-8517, if you are interested.
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Do you have a loved one with agitation associated with Alzheimer’s dementia? Is their agitation becoming overwhelming? Examples of some easily identifiable agitated behaviors are: restlessness, screaming, shouting, throwing things, resistiveness, constant unwarranted requests for attention or help, pacing/aimless wandering, kicking, hitting others or self, pushing people, hurting self or others, tearing things or destroying property. In this study, researchers want to find out if an investigational drug called AVP-786 is safe and effective (useful) in managing agitation in adults with Alzheimer’s dementia, when compared to a placebo. If you are a caregiver for a person with Alzheimer’s disease, please call (205) 996-5987 or email lalexander@uabmc.edu for more information.

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We are enrolling opioid users without a history of psychosis, endocrine diseases, inflammatory diseases, or autoimmune diseases. If you meet these criteria you may be eligible to participate in a research study. Compensation provided up to $20. For more information, please call the UAB Office of Psychiatric Research at 205-934-8336.
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You may be eligible to participate in a research study about the effects of Exercise and Metoprolol (a blood pressure pill) on a protein in your blood. This protein is related to heart disease. Eligible participants must be Healthy men and women, African American or Caucasians and have no history of diabetes, heart problems, or kidney problems. The study involves performing exercise, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please e-mail Nehal Vekariya at nvekariya@uabmc.edu if you are interested.
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You may be eligible to participate in a research study about the effects of sacubitril/valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves performing some exercise, taking sacubitril/valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Nehal Vekariya at nvekariya@uabmc.edu if you are interested.
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UAB's Urogynecology and Pelvic Reconstructive Surgery is conducting a 3 month at-home non-invasive lower leg stimulation study. You may be eligible if you are female and 18 years of age and older, have a history of chronic Bowel Leakage for at least 6 months, and have tried at least 2 treatments, including medications, diet, and pelvic exercises. Compensation will be provided. If you would like more information about the study, please contact 205-934-5498.
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Are you taking Metformin alone or metformin with a sodium-glucose transport protein 2 (SGLT2) inhibitor to treat your diabetes? The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a 39-week research study to see how two new study medicines work together on blood sugar levels in people with Type 2 diabetes. Qualified participants will receive study-drug free of charge and may be compensated for time and travel. For more information, and to check your eligibility to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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You may be eligible for a research study if you are a female 18 or older and have been diagnosed with endometriosis. Study medication and clinic visits provided at no cost. Compensation provided for every visit. Please call 205-934-1322 or email slangan@uabmc.edu to hear more information.
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The purpose of the study is to measure maximum walking speed and step length with virtual reality and customizable exercise games as feedback sources on a robotic treadmill. The targeted population is individuals with hemiparesis, in a chronic and stable stroke stage, who are able to follow instructions, and able to walk independently for at least three minutes. Based on a phone screening, eligible participants will attend up to two separate sessions at UAB Spain Rehabilitation Center. In each session, they will go into different walking or stepping performance conditions. The session will last about two hours, and participants will be paid 30$ per session for their time and effort. For more information please call Saleh Alhirsan at (205) 261-3853 or by email atalhirsan@uab.edu.
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We are looking for adults between 21-55 years old and diagnosed with Attention Deficit and Hyperactivity Disorder (ADHD), and use stimulant medication to participate in our study. We want to determine the role of ADHD stimulant medication on balance and other factors, such as physical activity in improving balance performance. We hypothesize that ADHD will improve balance performance in adults with ADHD. We also hypothesize that moderate to vigorous physical activity behaviors will positively influence balance performance in this population. Participants will be required to make two visits. Once on-medication; and on the second visit, we will ask participants to forgo ADHD medication 24 hours before the testing. For more information please contact Mansour at (205) 503-2977, or by email at amansour@uab.edu.
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The purpose of the SCIPE study is to examine two 8-week remotely delivered exercise interventions: Movement-to-Music, and Standard Exercise Training. Enrolled participants will be randomized into one of three groups: M2M, SET, or attention control. The primary goal of this study is to examine changes in physical activity levels after the 8-week M2M and SET interventions. We hypothesize that M2M and SET participants will have significant increases in physical activity, sleep quality, quality of life, and decreases in pain compared to the Attention Control group after the 8-week intervention. The secondary aim is to examine the effects of the M2M and SET interventions on health and quality of life outcomes. Exercise enjoyment in M2M and SET participants will also be explored. The tertiary aim is to evaluate the demographic, clinical, and psychosocial variables of two participant groups: 1) compliant participants who completed ≥ 50% of the intervention, and 2) non-compliant participants who completed post-testing but only 50% of the intervention, or did not complete post-testing. The SCIPE study will take place entirely online. The exercise program will be delivered to you in a video format, so you can exercise anywhere that is convenient for you. For more information please contact (205) 209-2245 or email scipe@uab.edu.
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Then you may be eligible for a research study. If you are female ages 18-49 and were diagnosed with endometriosis in the last 10 years, you may qualify to receive study medication at no cost to you. For more information call 205-934-1322 or email slangan@uabmc.edu. Compensation provided for completed visits.
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If you are 18 years of age or older and currently taking the blood thinners Xarelto (rivaroxaban) or Eliquis (apixaban), you may be eligible to participate in a research study. This study is being done to determine how your kidney function affects how you metabolize Xarelto or Eliquis. The study involves keeping a medication log for one week and one (12 hour) visit to UAB where we will collect blood samples at different times during the day. Participants will be compensated $150 for completing the one-day study visit. If you are interested or for more information, please contact our research team at pkpdstudy@uabmc.eduor 205-917-9800.
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You may be eligible to participate in a research study about the effects of Sacubitril/Valsartan on how your body handles insulin and glucose. This medication is related to the heart. Eligible participants must be healthy men and women, African American, and have no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking sacubitril/valsartan or valsartan, and collecting blood samples. Participants will be compensated. Please e-mail Dr. Vibhu Parcha, vparcha@uabmc.edu if you are interested. 
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You may be eligible to participate in a research study about the effects of exercise and Metoprolol, a blood pressure pill, on a protein in your blood. This protein is related to heart disease. Eligible participants must be healthy men and women, African American or Caucasian with no history of diabetes, heart problems, or kidney problems. The study involves exercising, taking metoprolol, consuming prepared meals, and collecting blood samples. Participants will be compensated. Please email Dr. Vibhu Parcha at vparcha@uabmc.edu if you are interested.
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The RECOVER study will investigate the use of Vagus Nerve Stimulation (VNS) Therapy in up to 1,000 people across the United States. To join the RECOVER study you must be 18 years or older and: currently depressed, have bi-polar depression that has lasted for at least two years or recurred several times, and have tried at least four types of antidepressant treatments and not found them helpful. Please leave a voice message at (205) 975-0068 or email candacegreen@uabmc.edu for more information.

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If you are at least 18 years of age, can read and write in English, are generally healthy, and have no history of mental illness or psychiatric disorders, please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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You may be able to participate in this study if you: are 18 years of age or older, have been diagnosed with major depressive disorder, MDD, and have not adequately responded to at least 2 different antidepressant treatments. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have Major Depressive Disorder (MDD) that hasn’t responded to anti-depressant medication, learn about this research study of an investigational drug for MDD. As part of their study participation, patients will be regularly evaluated and closely monitored by a team of medical professionals. To pre-qualify for this study, you must: be 18 to 65 years of age; have been diagnosed with MDD; be in a current depressive episode for at least 8 weeks but not more than 12 months; and have been taking an antidepressant medication for at least the last 8 weeks. Additional criteria will apply. All study-related visits, tests, and study drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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This is a paid research opportunity for adults who provide care for adult loved ones 45 years or older. We are actively recruiting for a research study to examine caregivers’ experiences and health outcomes. To be eligible, caregiver participants need to commit to providing care for their loved ones at least five hours weekly, and their loved ones need to be ages 45 and older. The study takes approximately 45 minutes to complete and can be completed via our online survey or over the phone with one of our trained research assistants. Participants will receive a $20 gift card for completing the study. The link to complete the study is: https://uab.co1.qualtrics.com/jfe/form/SV_bmAfy0dohaFEciG. For more information, please call and leave a voicemail for our research lab at (205) 975-9452, or email Wesley Browning at wbro9119@uab.edu, or Celine Atkins at gcat347@uab.edu.
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The University of Alabama at Birmingham, Department of Nutrition Sciences, is conducting a research study to evaluate the effectiveness of an investigational drug to treat people with Type 2 Diabetes and obesity. To qualify, you must have Type 2 Diabetes, older than 18 years old, moderately overweight, diet-controlled or taking oral diabetes medications. Qualified participants will receive the study drug free of charge and compensation for time and travel. For more information, and to see if you might be eligible to join, please contact (205) 996-4015 or email at ccnrn@uab.edu.
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Looking for individuals between the ages of 18-70 with a diagnosis of traumatic brain injury, spinal cord injury, spina bifida, cerebral palsy, stroke, Parkinson disease, or multiple sclerosis to participate in Movement-to-Music (M2M), a rhythmic-based exercise program provided entirely remotely from Lakeshore Foundation. You may be eligible if you have stable cardiovascular conditions and have not participated in a similar research study in the past 6 months. All equipment for completing the program and additional compensation provided. To learn more about this opportunity and if you are eligible, please call Lori Theriot at (205) 313-7455 or email m2mstudy@uab.edu.
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We are looking for adults with type 2 diabetes for a research study to see if eating large amounts of whole fruit can improve your blood sugar and reduce your need for diabetes medications. You may be eligible if you are 20-65 years old, overweight (BMI 27-45), diagnosed with type 2 diabetes within the last 6 years, and are not taking insulin. Participants will be provided with meals for 12 weeks, a high-speed Vita-Mix blender, and $1,375 for completing the study. Since this study is time-intensive, we are seeking only highly motivated and dedicated participants. If you are interested, please complete the brief electronic form at http://bit.ly/fruit_study. For more information, please contact Cody Hanick at chanick@uab.edu or (262) 923-0672.
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We are looking for adults with type 2 diabetes for an exciting research study to see whether intermittent fasting and/or using light therapy can improve your blood sugar, improve your overall health, and reset your body clock. Participants will either eat early in the day, graze throughout the day, and/or use a special light therapy box or glasses. You may be eligible if you have type 2 diabetes, are 30-80 years old, are not taking insulin, and usually wake up between 5:00 and 9:00 am. The main part of the study lasts 16 weeks and involves two overnight tests in our clinic (which can be done on weekends, if preferred). Participants will receive $2400 for completing the study.

If you are interested, please follow the link http://bit.ly/clocksstudy to apply for the CLOCKS study. Or for more information, please contact our research team for more information at CLOCKSSTUDY@uab.edu or 205-484-7329 or 205-484-5633.

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We are looking for adults for an exciting research study to see whether meal timing can improve your blood sugar and your overall health. Participants will be randomly selected to either graze throughout the day, skip breakfast, or skip dinner for 8 weeks. You may be eligible if you are 30-70 years old, are overweight, are not taking diabetes medication, and wake up between 5:00 and 8:00 am regularly. Adults with prediabetes, blood sugar issues, or a family history of diabetes are encouraged to apply. This study involves two overnight tests in our clinic plus eating only food that we provide you. Participants will receive $1200 for completing the study and 8 weeks of meals, valued at a total of $2400. If you are interested, please visit https://bit.ly/mealtimingstudy to apply for the study. Or for more information, please contact one of our research coordinators at mealtiming@uab.edu or 205-975-3944.

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Is your child in good health without Diabetes, Hypertension, Hyperlipidemia, Thyroid dysfunction, Autoimmune diseases, Moderate to Severe Intellectual disability, or Taking medications affecting? If so, your child may be eligible to participate in a research study at UAB. Compensation up to $140 for two visits, each visit lasting 5 hours. For more information, please call the UAB Office of Psychiatric Research at Call: 205-975-4207
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Healthy men and women, ages 18 to 75, are needed for a study exploring the reason why individuals who have diabetes have an increased risk of forming a calcium oxalate kidney stone. The study involves consuming prepared meals over 4 days and collecting urine and blood. Compensation $130. Please phone Demond at 205-934- 5712 or email kidneystone@uabmc.edu, if you are interested.
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Adults ages 18-89 with history of kidney stones needed for a study Individuals ages 18-89 years with a history of Calcium Oxalate kidney stones, are needed for a study exploring factors that impacting oxalate metabolism in kidney stone formers. The study involves consuming prepared meals over 4 days and collecting urine and blood. Compensation up to $140. For more information, call 205-934-5712 or email kidneystone@uabmc.edu or kidneystoneresearch@uabmc.edu.
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Major Depressive Disorder patients may be able to contribute to our understanding of depression. If you have Major Depressive Disorder (MDD) that hasn’t responded to anti-depressant medication, learn about this research study of an investigational drug for MDD. As part of their study participation, patients will be regularly evaluated and closely monitored by a team of medical professionals. To pre-qualify for this study, you must: be 18 to 65 years of age; have been diagnosed with MDD; be in a current depressive episode for at least 8 weeks but not more than 12 months; and have been taking an antidepressant medication for at least the last 8 weeks. Additional criteria will apply. All study-related visits, tests, and study drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Get involved in a research study that aims to understand how chronic pain from knee osteoarthritis may change learning. We are looking for adults aged 40-65 with knee pain due to osteoarthritis who are willing to have their brains scanned during a learning procedure. The commitment to this study will last approximately 2 hours and include one telephone screen and one visit to UAB where you will fill out questionnaires and have your brain scanned with magnetic resonance imaging (MRI) during a learning task. If you are eligible to participate in this study, you will receive up to $50. We are also recruiting healthy controls with no chronic pain. If you are interested, please send a message to foamstudy.uab@gmail.com or call 205-234-1201.
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Researchers at the Alabama Vaccine Research Clinic at UAB are looking for volunteers between the ages of 18 and 50 to participate in HIV vaccine research studies. Procedures include the collection of medical and sexual history, blood and urine samples for lab testing, and a physical exam. Additional tests, such as STI testing, electrocardiograms, pap smears, and pregnancy testing may also be required. Screening visit compensation is $20, with additional compensation earned for study participation. You cannot get HIV from the vaccine. For more information, please call 205-934-7492 or email avrc@uabmc.edu.
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Researchers in the School of Medicine are recruiting people from the general public age 18 years or older to participate in a research study. The study is one remote visit that consists of filling out questionnaires online. The purpose of the study is to examine the racial differences in sleep patterns as it relates to cigarette smoking and smoking dependence. Results from this study may help in designing better treatments for quitting smoking. If you are eligible and decide to enroll, this study will take approximately one hour to complete, and you will be compensated $40 for your time. To see if you qualify go to: https://bit.ly/3wjtT2F
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please leave a voice message at (205) 934-2484 or email lalexander@uabmc.edu for more information.
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We are seeking volunteers for a research study looking at the role of different components of a lifestyle intervention program in family medicine clinics. The study will last approximately 6 months. Participants will receive nutrition or exercise counseling and receive body composition scans and lab work at no charge. Participants will receive weekly counseling sessions for the first 2 months of the study, and bi-monthly counseling sessions for the remaining 4 months of the study. Participants will receive monetary stipends totaling $300 to reimburse for time and travel to study visits. You may qualify for this research study if you: Are 18-75 years old. Not pregnant or lactating. Have a BMI of ≥ 27 kg/m² - Check your BMI at:http://www.nhlbi.nih.gov/health/educational/lose_wt/BMI/bmicalc.htm. Are willing to participate in regular counseling sessions and attend 4 study visits at UAB’s Family and Community Medicine clinic over the course of the 6-month study. Please call 205-975-4113 or email reba0315@uab.edu if you are interested.
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Junghee Lee, Ph.D. (UAB Psychiatry) is looking for healthy volunteers without any psychiatric illness to participate in a study called “Disrupted Social Preference in Early Psychosis.” The main purpose of this research project is to gather information on the nature of problems in social information processing in persons with schizophrenia compared to community controls. You will be compensated $25/hour and up to $260 for your participation. If you are between 18 and 35, have no history of problematic drug or alcohol use for the past three months, and no history of neurological disorders or psychiatric problems, please call (205) 934-8203 or email our lab team at nlsb.uab@gmail.com for further information.
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African American men and women ages 50-65 needed for study on lifetime stress and brain functioning. We want to pay people who identify as African American/Black to help us see if stress and other lifestyle factors can protect their mental health and their brain health. This knowledge is especially important to understand as people face difficult situations and might be at risk for Alzheimer’s disease. All information collected will be kept confidential. The study involves two visits lasting 2-3 hours each, including one MRI at UAB Highlands Hospital. A check of $75 will be mailed to you at the end of the study. For more information, visit: http://immcdonough.people.ua.edu/participate.html or leave a voice message at 205-348-2808.
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The Neuroinflammation, Pain, and Fatigue Lab is looking for women ages 18-55 who have symptoms of Chronic Fatigue Syndrome, ME/CFS, for a 1.5-hour brain imaging study. We will obtain magnetic resonance images, MRI, of your brain for one hour. The brain scans are non-invasive and do not involve exposure to radiation or injection of contrast agents. There will also be questionnaires. The purpose of the study is to investigate whether patients with chronic fatigue have increased brain temperature compared to healthy people. If interested, please contact Indonesia Jordan at 205-289-8748, or email ijordan@uab.edu with your name and phone number.
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Women with Relapsing-Remitting Multiple Sclerosis (RRMS) needed for brain-imaging study The Neuroinflammation, Pain, and Fatigue Lab is looking for women with relapsing-remitting Multiple Sclerosis ages 18-65 for a brain imaging study. The study includes a phone interview and two visits to UAB hospital: one screening visit including blood draws, and one imaging visit, during which we will acquire Positron Emission Tomography (PET) and Magnetic Resonance Images (MRI) of your brain for one hour. PET imaging involves exposure to a small amount of radiation. There will also be questionnaires. You will be paid $400 for completing the study. The purpose of the study is to investigate whether patients with multiple sclerosis have increased brain inflammation compared to healthy people. If interested, please contact Chloe Jones at chloej@uab.edu" contenteditable="false">chloej@uab.edu or P: 205-434-1502, and leave your name and phone number.
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Recovering from COVID-19?Still have problems with confusion, slow thinking, or memory? If so, you may eligible to take part in a study testing a new form of cognitive training designed to improve how quickly you process information and perform daily activities. The study pays participants $20 per training session on average. The training program, which requires several visits to UAB, can be tailored to fit your schedule. If you are interested, please call 205-934-9768 or email stacemc@uab.edu.
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We are looking for Healthy Controls to participate in a study to examine racial differences in the experience of chronic low back pain. To participate in this study, you must have no chronic pain, between the ages 30-85 years old, receive medical services at UAB, no serious medical conditions and be able to attend two testing sessions one week apart. Participants will receive up to $400 for completing the study. You may not be eligible to participate if you have significant health problems or are taking certain medications. Please contact Tammie at tquinn@uab.edu or call 205-934-8743. Leave a short message with your name, number, and mention that you are interested in the ERASED study.
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We are looking for healthy individuals to participate in a study to examine the effects of buprenorphine and baclofen in humans. This pilot study will be used to gather initial evidence to assess the analgesic interaction, safety, acceptability, and feasibility of using buprenorphine and baclofen in humans before conducting a larger clinical trial to examine efficacy in patients. We will be giving participants a one-time low dose of a partial opioid agonist buprenorphine or baclofen. Participants will be required to attend two visits one week apart and asked to complete questionnaires, pain testing, and a blood draw. Participants will receive up to $150 for completing the study. You may not be eligible to participate if you have significant health problems, are pregnant, or are taking certain medications. Please contact Tammie at tquinn@uab.edu or call 205-934-8743. Leave a short message with your name, number, and mention that you are interested in the BACUP study.
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We are looking for individuals to participate in a study that aims to gain a better understanding of risk factors for insomnia in people with and without the human immunodeficiency virus (HIV) and to observe its effects on pain sensitivity and inflammation. This study will consist of several various in-person visits that span from 3 visits within an 8-day period, and if qualified for the second branch of this study, an additional 6 visits once a week for the following 6 weeks. During the visits, participants will be asked to complete a sleep interview, wear a sleep device overnight, answer questionnaires, as well as perform pain testing and blood draws. Participants will be compensated appropriately for their time. You may qualify if you have good or bad sleep and are above the age of 18. We are recruiting both individuals who are HIV positive and individuals who are HIV negative. Please contact Dyan at dywhite@uab.edu or call 205-934-8734. Leave a short message with your name, number, and mention that you are interested in the HIPPI study.
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The Better BP study is currently enrolling 660 adults to take part in a research study about how to measure blood pressure. We are seeking adults older than 19 years of age who are not currently taking medications for high blood pressure, have no history of cardiovascular disease or major arrhythmias, no known sleep apnea and not known to be currently pregnant. Participants will be compensated $150 for completing four study visits in the UAB Hypertension Research Clinic located at the 19th Street Community Health Bldg. To confirm your eligibility for this study, please call 205-934-1400 or email bpstudy@uab.edu to schedule your telephone screening, which should take approximately 10 minutes.
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This study is being done to assess how well individuals can modify walking patterns. If you qualify, we anticipate that your participation in the study will span a single study visit, with a total time commitment of 3 hours. You will be compensated for your time. Please e-mail Daniel Kuhman at dkuhman@uab.edu or contact him by phone at 205-934-0416 if you are interested.
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You may be eligible to participate in a UAB research study comparing medications if you are 18 years of age or older, in good physical health, and have tried at least one antidepressant medication. You must be in a current depressive episode, feeling sad, down, hopeless, guilty, tense, or irritable.  You will receive compensation for your time. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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If you have major depressive disorder (MDD) and are in a current depressive episode, we invite you to learn about a research study of an investigational drug that is taken with your current antidepressant medication. In this study, researchers will evaluate the safety and efficacy of the investigational drug as an add-on therapy to your current antidepressant medication. To prequalify for this study you must be 18 to 65 years of age, have been diagnosed with recurrent MDD, be in a current major depressive episode for at least the last 8 weeks, and not experiencing a satisfactory improvement in your symptoms of depression with your current treatment. All study-related visits, tests, and drugs will be provided at no cost. In addition, reimbursement for study-related travel may be provided. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Are you in good physical health? Are you Caucasian/white? Are you between the ages of 34 and 65? Have you never been diagnosed with a psychiatric condition? If so, you may be eligible to participate in a study requiring a one-time blood draw. Compensation provided. Please call (205) 934-2484 or email lalexander@uabmc.edu for more information.
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Heterosexual sexually active women ages 18-45 needed for study exploring how bacterial vaginosis (BV), the most common vaginal infection, occurs in women. If eligible, the study involves an anonymous survey, STD testing, and completion of twice-daily sexual/reproductive diaries, and self-collection of 3 twice daily vaginal swabs over an 8 week time period. Volunteers will be compensated $20 for screening, $25 for the enrollment visit, $20/week for drop-off of daily diaries and specimens (weeks 1-7), and $50 for the final weekly drop-off (week 8). Please call 205-934-8166 for more information.
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This study is being done to better understand sexual health in the transgender community. Eligible volunteers will be compensated. If interested, please call (205) 934-8166.
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